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Zheng H.,Jiangyin Traditional Chinese Medical Hospital | Chen C.,Jiangyin Traditional Chinese Medical Hospital
BMJ Open | Year: 2015

Objectives: Obesity is suggested to be a risk factor for knee osteoarthritis (OA). This meta-analysis aimed to examine the relationship between body mass index (BMI) and the risk of knee OA in published prospective studies. Design: Meta-analysis. Studies reviewed: An extensive literature review was performed, and relevant studies published in English were retrieved from the computerised databases MEDLINE, EMBASE and Cochrane. Methods: The effect estimate (RR or HR) and its 95% CI are investigated on the basis of the evaluation of differences of knee OR risk in overweight or obesity versus those with normal weight. Category-specific risk estimates were further transformed into estimates of the RR in terms of per increase of 5 in BMI by using the generalised least-squares method for trend estimation. Studies were independently reviewed by two investigators. Subgroup analysis was performed. Heterogeneity and publication bias were assessed. Data from eligible studies were extracted, and the meta-analysis was performed by using the STATA software V.12.0. Results: 14 studies were finally included in the analysis. The results showed that overweight and obesity were significantly associated with higher knee OA risks of 2.45 (95% CI 1.88 to 3.20, p≤0.001) and 4.55 (95% CI 2.90 to 7.13, p≤0.001), respectively. The risk of knee OA increases by 35% (95% CI 1.18 to 1.53, p≤0.001) with a 5 kg/m2 increase in BMI. Subgroup analysis showed that obesity was an independent predictor of knee OA risk regardless of the study country, sample size, gender proportion of participants, duration of follow-up, presence of adjusted knee injury and assessed study quality above or below an NOS score of 8. No publication bias was detected. Conclusions: Obesity was a robust risk factor for knee OA. Professionals should take a possible weight reduction into account for the treatment of knee OA whenever a patient is significantly overweight. Source


Chen C.-H.,Suzhou University | Dong Q.-R.,Suzhou University | Zhou R.-K.,Jiangyin Traditional Chinese Medical Hospital | Zhen H.-Q.,Jiangyin Traditional Chinese Medical Hospital | Jiao Y.-J.,Jiangyin Traditional Chinese Medical Hospital
International Journal of Clinical and Experimental Medicine | Year: 2014

Introduction: Internal fixation with hook plate has been used to treat acromioclavicular joint dislocation. This study aims to evaluate the effect of its use on shoulder function, to further analyze the contributing factors, and provide a basis for selection and design of improved internal fixation treatment of the acromioclavicular joint dislocation in the future. Methods: A retrospective analysis was performed on patients treated with a hook plate for acromioclavicular joint dislocation in our hospital from January 2010 to February 2013. There were 33 cases in total, including 25 males and 8 females, with mean age of 48.27 ± 8.7 years. There were 29 cases of Rockwood type III acromioclavicular dislocation, 4 cases of type V. The Constant-Murley shoulder function scoring system was used to evaluate the shoulder function recovery status after surgery. Anteroposterior shoulder X-ray was used to assess the position of the hook plate, status of acromioclavicular joint reduction and the occurrence of postoperative complications. Results: According to the Constant-Murley shoulder function scoring system, the average scores were 78 ± 6 points 8 to 12 months after the surgery and before the removal of the hook plate, the average scores were 89 ± 5 minutes two months after the removal of hook plate. Postoperative X-ray imaging showed osteolysis in 10 cases (30.3%), osteoarthritis in six cases (18.1%), osteolysis associated with osteoarthritis in four cases(12.1%), and steel hook broken in one case (3%). Conclusion: The use of hook plate on open reduction and internal fixation of the acromioclavicular joint dislocation had little adverse effect on shoulder function and is an effective method for the treatment of acromioclavicular joint dislocation. Osteoarthritis and osteolysis are the two common complications after hook plate use, which are associated with the impairment of shoulder function. Shoulder function will be improved after removal of the hook plate. © 2014, International Journal of Clinical and Experimental Medicine. All rights reserved. Source


Chen C.-H.,Jiangyin Traditional Chinese Medical Hospital | Zhou R.-K.,Jiangyin Traditional Chinese Medical Hospital | Zhen H.-Q.,Jiangyin Traditional Chinese Medical Hospital | Huang L.,Jiangyin Traditional Chinese Medical Hospital | Jiao Y.-J.,Jiangyin Traditional Chinese Medical Hospital
International Journal of Clinical and Experimental Medicine | Year: 2015

Objective: To compare the efficacy of volar and dorsal plate fixation for unstable dorsal distal radius fractures. Methods: Forty-seven cases were selected from patients undergoing surgical reduction and internal fixation treatment in our hospital from August 2006 to October 2010, with 21 males and 26 females, aged 39-73 years old. Patients were divided into two groups: volar plate fixation group (Group A) which has 32 cases, including 27 cases with locking plate, 5 cases with ordinary T plate, and 4 cases combined with dorsal Kirschner wire fixation; dorsal plate fixation group (Group B) which has 15 cases, including 7 cases with locking plate. The efficacy of the two fixation methods were compared in terms of postoperative wrist function, X-ray score, and postoperative complications. Results: Compared with those of preoperative groups, the volar tilt, ulnar deviation and radial styloid height in both group A and B were significantly improved one week after surgery as shown by X-ray imaging. Comparison of X-ray images one week after surgery with those of six months after surgery showed no significant changes in volar tilt, ulnar deviation or radial styloid height. 87.5% of patients in group A and 86.7% of patients in group B got “excellent” in their wrist function assessment, and there was no significant difference between the two groups (X2=0.825, P=1.000). But patients in group A hax significantly lower incidence rate of postoperative complications than group B (X2=4.150, P=0.042). Conclusion: For unstable distal radius fractures with dorsal displacement, volar plate fixation can achieve satisfactory reduction results, and cause less tendon damage or other complications than dorsal plate fixation. © 2015, Int J Clin Exp Med. All rights reserved. Source

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