Jiangsu Zhongdan Pharmaceutical Research Institute Co.

Nanjing, China

Jiangsu Zhongdan Pharmaceutical Research Institute Co.

Nanjing, China
SEARCH FILTERS
Time filter
Source Type

Chen J.,Nanjing University of Technology | Zhu L.,Nanjing University of Technology | Xie H.,Nanjing University of Technology | Zhang J.,Nanjing University of Technology | And 5 more authors.
Polymer International | Year: 2014

We report a facile strategy for fabricating fluorescent quantum dot (QD)-loaded microbeads by means of microfluidic technology. First, a functional fluorine-containingmicroemulsionwas synthesizedwith poly[(2-(N-ethylperfluorobutanesulfonamido)ethyl acrylate)-co-(methyl methacrylate)-co-(butyl acrylate)] (poly(FBMA-co-MMA-co-BA)) as the core and glycidyl methacrylate (GMA) as the shell via differential microemulsion polymerization. Then, CdTe QDs capped with N-acetyl-L-cysteine (NAC) were assembled into the poly(FBMA-co-MMA-co-BA-co-GMA) microemulsion particles through the reaction of the epoxy group on the shell of the microemulsion and the carboxyl group of the NAC ligand capped on the QDs. Finally, fluorescent microbeads were fabricated using the CdTe QD-loaded fluorine-containing microemulsion as the discontinuous phase and methylsilicone oil as the continuous phase by means of a simple microfluidic device. By changing flow rate of methylsilicone oil and hybrid microemulsion system, fluorescentmicrobeads with adjustable sizes ranging from 290 to 420 μm were achieved. Themorphology and fluorescent properties of the microbeads were thoroughly investigated using optical microscopy and fluorescence microscopy. Results showed that the fluorescent microbeads exhibited uniform size distribution and excellent fluorescence performance. © 2014 Society of Chemical Industry.


Sun R.,Nanjing University of Technology | Yao C.,Nanjing University of Technology | Chen J.,Jiangsu Zhongdan Pharmaceutical Research Institute Co. | Feng Y.,Jiangsu Zhongdan Pharmaceutical Research Institute Co.
Speciality Petrochemicals | Year: 2010

A GC-MS method was established to analyze the impurities of p-phenetidine sample. The structure of the impurities were identified to be N-methyl-4-ethoxybenzenamine, N-ethyl-4-ethoxy-benzenamine, N-methoxy-4-ethoxybenzenamine, N-(4-ethoxybenzenamine) phenyl-1, 4-diamine and N 1-ethoxy-N 4-Cethoxybenzenamine) phenyl-1,4-diamine by MS, and indicated that the impurities mainly resulted from the reaction conditions and the solvent methanol. This GC-MS method is very useful for the later research.

Loading Jiangsu Zhongdan Pharmaceutical Research Institute Co. collaborators
Loading Jiangsu Zhongdan Pharmaceutical Research Institute Co. collaborators