Jiangsu Union Technical Institute
Jiangsu Union Technical Institute
Wang N.,Jiangsu Union Technical Institute |
Zhu X.,Jiangsu Union Technical Institute |
Zhang J.,Soochow University of China
Proceedings - 12th International Conference on Computational Intelligence and Security, CIS 2016 | Year: 2016
In order to make the computer own the knowledge about Chinese vehicle license plate segmentation and recognition, the paper put forward a set of algorithms about license plate segmentation and recognition. The algorithms are divided into four parts: image preprocessing, license plate location, license plate segmentation and character recognition. The aim of image preprocessing is quickly and easily location the license plate, so the image preprocessing algorithm is one of the important factors that affect total system performance. Because the algorithm of license plate location directly affects the accuracy of character segmentation and character recognition. So, the algorithm of license plate location is proposed according to characteristics of Chinese vehicle license plate. The algorithm of license plate segmentation uses the vertical projection method about license plate in this paper. According to the license plate segmentation character, the training model can be generated using tool of BPNN(back propagation neural network), which is the key of the character recognition algorithm about license plate. The results of experiment based the algorithms in the paper illustrate that accuracy rate of character recognition is very high, and the algorithms can fully meet the actual demand of automatic recognition. The algorithms can take advantage of the training model to perfectly realize recognition the license plate, and have application value in the real work. © 2016 IEEE.
Jiang S.,Peoples Hospital of Jiangsu Province |
Jiang S.,Jiangsu Union Technical Institute |
Miao B.,Xuzhou Medical University |
Chen Y.,Peoples Hospital of Jiangsu Province
NeuroReport | Year: 2017
Postoperative cognitive dysfunction is a frequent complication with surgery and anesthesia, and the underlying mechanism is unclear. Our aim was to investigate the effect of different durations of isoflurane anesthesia on spatial recognition memory and activation of JNK1/2 in the hippocampus of mice. In the present study, adult male mice were anesthetized with isoflurane for different durations (1.5% isoflurane for 1, 2, and 4 h). Spatial recognition memory was determined using spontaneous alternation and two-trial recognition memory in Y-maze at 24 h after anesthesia. The activation of JNK1/2 in the hippocampus was tested using western blot. Mice treated with isoflurane for 4 h showed significantly decreased spontaneous alternations and decreased exploration parameters compared with the no anesthesia group, but this was not observed in mice treated with isoflurane for 1 or 2 h. The protein levels of p-JNK1/2 in the hippocampus were significantly increased at 10 min after isoflurane anesthesia for 1, 2, and 4 h compared with no anesthesia. However, only isoflurane anesthesia for 4 h still increased JNK1/2 and p-JNK1/2 levels at 24 h after anesthesia. We concluded that prolonged duration of isoflurane anesthesia maintained the activation of JNK1/2, which led to memory impairment at 24 h after anesthesia. © 2017 Wolters Kluwer Health, Inc. All rights reserved.
Su S.,Nanjing University |
Hua Y.,Nanjing University |
Wang Y.,Jiangsu Union Technical Institute |
Gu W.,Nanjing University |
And 5 more authors.
Journal of Ethnopharmacology | Year: 2012
Aim of the study: The Chinese herbs of myrrh and frankincense are often combined for treating some inflammatory pain diseases with synergistic therapeutic effects. In this study, we investigated the effects of individual herbal extracts and combined extract on anti-inflammatory and analgesic activities in vivo and analyzed the potential bioactive components from the combination extract by ultra-performance liquid chromatography coupled with mass spectrum (UPLC-MS/MS). Materials and methods: The anti-inflammatory activities were investigated by utilizing the paw edema mice induced by formalin and carrageenan. In addition, we determined the levels of PGE 2 and nitrite in the edema paw. The analgesic activity was examined against oxytocin-induced dysmenorrhea in mice. The effects of the administration of dolantin or indomethacin were also studied for references. The components in combination extract (CWE) were analyzed by UPLC-MS/MS. Results: The results showed that myrrh water extract (MWE) and the combined extract (CWE) at the 3.9 g/kg, and 5.2 g/kg showed inhibition of formalin-induced paw edema with inhibition rate of 30.44%, and 23.50%, respectively. The PGE 2 production was inhibited significantly by all samples (P < 0.01 or P < 0.05). CWE showed stronger suppression on carrageenan-induced mice paw edema at 2 and 3 h after administration of drugs. The inhibitory effect of CWE on nitrite production was between that of MWE and water extract of frankincense (FWE) at 5.2 g/kg. The dysmenorrhea mice test showed MWE could remarkably reduce the writhing times (P < 0.05) and prolong the latency period, while FWE showed no obvious effects on the writhing times. CWE significantly reduced the writhing times and prolong the latency period (P < 0.01). Conclusion: These results demonstrated MWE, FWE, and CWE exhibited significant anti-inflammatory and analgesic activities. The findings suggest that CWE may be therapeutically more useful for mitigating inflammatory pain than individual herbal extract. In addition, 12 potential active compounds were identified from CWE. These data may support the fact the traditional application of this combined extract in treating various diseases associated with inflammatory pain. © 2011 Elsevier Ireland Ltd.
Li P.,Jiangsu Union Technical Institute
International Journal of Biomedical Engineering and Technology | Year: 2017
In recent years, with microelectronics, computer, communications, and the other information technology applications in the medical and health cause has entered the new era of information. In the IT technology to every corner in the field of medical rapid extension and penetration of the today, the information system integration is becoming more and more an important hot spot in the study of medical informatisation. From the 1980s of the DICOM and HL7 of these industry standards, to the IHE founded in the 1990s, people have never stopped to enhance the communication between manufacturers, efforts to make medical institutions more efficient. To deal with the challenges, this paper designs and implements the novel medical cloud database service system based on the parallel and the mobile computing. We integrate the parallel and the mobile computing techniques to enhance the system to achieve the goal of obtaining higher robustness and efficiency. The experimental result proves that our multicore parallel system can get higher robustness and efficiency. At the same time, the real-word user interface is demonstrated to provide the intuitive understanding. © 2017 Inderscience Enterprises Ltd.
Chen Y.,First Peoples Hospital of Lianyungang |
Jiang S.,Jiangsu Union Technical Institute |
Wu Y.,First Peoples Hospital of Lianyungang
Medicine (United States) | Year: 2016
Hypertensive patients in neurosurgery are becoming more common, which increased the risk of surgical stress response. Meanwhile, the relationship between hypertension and anesthesia methods is unclear on the stress response. The purpose of this study is to compare the effect of different anesthesia methods on high-sensitivity C-reactive protein (Hs-CRP), blood glucose, and leucocyte levels in neurosurgical patients with hypertension or normal. Eighty neurosurgical patients were randomly divided into 4 groups (n=20): balanced anesthesia group (A), balanced anesthesia with hypertension group (B), total intravenous anesthesia group (C), total intravenous anesthesia with hypertension group (D). The levels of Hs-CRP, blood glucose, leucocyte count, and neutrophil percentage and were detected at before anesthesia (T0), during anesthesia (T1), 2hours post anesthesia (T2), 24hours post anesthesia (T3). Patients with hypertension had higher Hs-CRP expression, blood glucose, and neutrophil percentage at time T0 than those of normal, but not leucocyte count. At time T3, patients with hypertension in D group had lower Hs-CRP expression than those in B group (P<0.01). Patients with normal in C group had lower Hs-CRP expression (P<0.01), blood glucose (P<0.05), and leukocyte count (P<0.05) than those in A group. Both hypertension history and anesthesia method had significant effects on the Hs-CRP expression, blood glucose, and leukocyte count. Total intravenous anesthesia decreases Hs-CRP expressions more efficiently than balanced anesthesia in neurosurgical patients with hypertension or normal. Moreover, total intravenous anesthesia can availably reduce the perioperative stress response by attenuating the increase of blood glucose and leukocyte count in normal tensive patients. Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All.
Yin J.,CAS Shanghai Institute of Applied Physics |
Yin J.,Jiangsu Union Technical Institute |
Kang C.,CAS Shanghai Institute of Applied Physics |
Li Y.,CAS Shanghai Institute of Applied Physics |
And 5 more authors.
Toxicology Research | Year: 2014
With the rapid development of nanoscience and nanotechnology, comprehensive evaluation of the potential toxicity especially the respiratory toxicity of nanomaterials, has attracted great research interest over the past few decades. A numerous previous reports have utilized intratracheal instillation to imitate the physiological inhalation exposure route of nanomaterials. However, because it is a non-physiological breathing process, intratracheal instillation has many problems when it is utilized to evaluate respiratory toxicity of nanomaterials. In this study, anatase titanium dioxide (TiO2) nanoparticles with a primary particle size of 20 nm was selected as a model nanomaterial. Its respiratory toxicity has been estimated by a whole-body exposure chamber. Mice were put in the whole-body exposure chambers with a relatively steady concentration (6.34 ± 0.22 mg m-3) of inhaled TiO2 nanoparticles. In the whole study these mice were exposed 8 h per day, for 3 weeks. Results showed that these TiO2 nanoparticles inhaled might drill through air-blood barriers, be metabolized by the liver and excreted by the urinary system. After mice had been exposed to TiO2 nanoparticles, H2O2 and maleic dialdehyde (MDA) in brain homogenate extracts had clearly increased. The white blood cell (WBC) count was decreased while platelet (PLT) and reticulocyte (Retic) counts increased significantly. At the same time, the prothrombin time (PT) of mice in the inhalation exposure group was shorter than the control group's. Furthermore, compared with the control group's, the levels of ALT, AST, BUN and CREA in the inhalation exposure group were elevated. Given the whole body exposure method is a physiological exposure route, the results reported in this work should be more suitable for evaluation of the respiratory toxicity of nanomaterials. This journal is © the Partner Organisations 2014.
Yao Z.,Nanjing Medical University |
Yao J.,Jiangsu Union Technical Institute |
He X.,Nanjing Medical University |
Li Z.,Jiangsu Union Technical Institute |
Liu Y.,Nanjing Medical University
Chinese-German Journal of Clinical Oncology | Year: 2013
Objective: The aim of the study was to investigate the apoptosis induced by piperlongumine on human breast adenoma MDA-MB-231 cells and the mechanism involved. Methods: Human breast adenoma MDA-MB-231 cells line was cultured in vitro. The inhibitory effect of piperlongumine on the proliferation of human breast adenoma MDA-MB-231 cells was measured by CCK-8 assay. Distribution of cell cycle was analyzed by flow cytometry. The apoptosis rates of MDA-MB-231 cells were measured using Annexin V/PI staining. The flow cytometry with the probe of DCFH-DA was used to detect the intracellular reactive oxygen species levels. Western blot was used to explore the protein expression of Bcl-2 and Bax. Results: The CCK-8 assay showed that piperlongumine had an inhibiting effect on the proliferation of MDA-MB-231 cells in a concentration- and time-dependent manner. MDA-MB-231 cells were markedly arrested at G0/G1 phase after treatment of piperlongumine. Piperlongumine induced apoptosis of MDA-MB-231 cells obviously. The level of intracellular reactive oxygen species was increased in a dose-dependent manner. The antioxidant N-acetyl-L-cystein inhibited the apoptosis of cells and the level of intracellular reactive oxygen species was also decreased. By Western blot analysis, we found the expression of Bax was up-regulated whereas that of Bcl-2 was down-regulated in a concentration-dependent manner. Conclusion: Piperlongumine possesses a significant function for inhibiting proliferation, arresting cells at G0/G1 phase and inducing apoptosis of MDA-MB-231 cells, which seems to be associated with the increased generation of intracellular reactive oxygen species as well as the down-regulation of Bcl-2 and up-regulation of Bax. © 2013 Springer-Verlag Berlin Heidelberg.
Yuping C.,JIANGSU Union Technical Institute
Proceedings - 14th International Symposium on Distributed Computing and Applications for Business, Engineering and Science, DCABES 2015 | Year: 2015
This paper presents a quantum particle swarm optimization solutions for the problem of license plate location, the first image of the vehicle local area adaptive illumination compensation image preprocessing, improving the quality of the picture. Then use the YCbCr color model signals a band compression to achieve illumination compensation. Based on this paper proposes a quantum particle swarm optimization algorithm, using less number of QPSO algorithm parameters, randomness is strong, and can cover all the solution space, to ensure global convergence of the algorithm. This paper presents the results of three pieces of plate positioning images prove local feature enhancement algorithm QPSO algorithm can perform feature extraction and stable positioning works well. © 2015 IEEE.
Zhu Y.D.,Jiangsu Union Technical Institute
Recent Advances in Electrical and Electronic Engineering | Year: 2016
The compression process of traditional image data compression method is complex, and has disadvantages like high computational complexity and low compression ratio. An image data compression transmission method based on singular value decomposition and wavelet transform is proposed and applied to multimedia network, the shortcomings of traditional method is analyzed, the singular value decomposition is applied to multimedia network image, and the energy ratio threshold is set, and relatively larger singular values are selected by self-adaption to complete the first stage compression of multimedia network image data. The threshold quantization method is utilized to process the high frequency coefficients under various resolution, the high frequency coefficients whose absolute value does not exceed the threshold is set to zero, so as to complete the image re-compression. The simulation results show that the proposed method can effectively enhance the image compression effect and reduce the complexity of the algorithm. © 2016 Bentham Science Publishers.
Yu D.,China Pharmaceutical University |
Li M.,China Pharmaceutical University |
Tian Y.,Jiangsu Union Technical Institute |
Liu J.,China Pharmaceutical University |
And 2 more authors.
Life Sciences | Year: 2015
Aims Luteolin is a falconoid compound that has an antioxidant effect, but its contribution to ROS-activated MAPK pathways in ischemia/reperfusion injury is seldom reported. Here, we have confirmed that it exhibits an antioxidant effect in myocardial ischemia/reperfusion injury (MIRI) by inhibiting ROS-activated MAPK pathways.Main methods We exposed rat hearts into the left anterior descending coronary artery (LAD) ligation for 30 min followed by 1 h of reperfusion. Observations were carried out using electrocardiography; detection of hemodynamic parameters; and testing levels of lactate dehydrogenase (LDH), creatine kinase (CK), total superoxide dismutase (T-SOD), and malondialdehyde (MDA). Mitogen-activated protein kinase (MAPK) pathway was measured by western blot and transmission electron microscopy was applied to observe the myocardial ultrastructure. Rat H9c2 cell in 95% N2 and 5% CO2 stimulated the MIRI. Oxidation system mRNA levels were measured by real-time PCR; mitochondrial membrane potential and apoptosis were measured by confocal microscopy and flow cytometry; western blot analysis was used to assay caspase-3, -8, and -9 and MAPK pathway protein expression; the MAPK pathway was inhibited using SB203580 (p38 MAPK inhibitor) and SP600125 (c-Jun NH2-terminal kinase inhibitor) before H9c2 cells were exposed to hypoxia/reoxygenation injury to show the modulation of the changes in ROS generation, cell viability and apoptosis.Key findings In vivo, luteolin can ameliorate the impaired mitochondrial morphology, regulating the MAPK pathway to protect MIRI. In vitro, luteolin can affect the oxidation system, mitochondrial membrane potential and MAPK pathway to anti-apoptosis.Significance These results reveal a ROS-MAPK mediated mechanism and mitochondrial pathway through which luteolin can protect myocardial ischemia/reperfusion injury. © 2014 Elsevier B.V. All rights reserved.