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Chi H.,University of Illinois at Chicago | Chi H.,Jiangsu Food and Pharmaceutical Science College | Keiderling T.A.,University of Illinois at Chicago
ChemBioChem | Year: 2017

β-Sheet conformation is promoted in peptides with amphiphilic design, and stable β-turn formation is favored with the unnatural amino acid d-Pro followed by a flexible residue such as Gly. A 19-residue peptide (B3) was synthesized with alternating hydrophobic and hydrophilic residues connected by symmetrical d-Pro-Gly and Gly-d-Pro turns. B3 forms an oligomeric aggregate, rich in β-sheet conformation, that reversibly transforms into an unordered structure on heating, as evidenced by its temperature-dependent IR spectra. When a dansyl moiety was added to the N terminus of B3, the resulting peptide (B3D) can convert into a fibrillar structure after higher temperature incubation, as detected spectroscopically as well as by TEM. The fibrillization process involves an initial unfolding step monitored by the quenching of dansyl emission; in contrast, subsequent enhanced thioflavin T emission is seen on its binding to the fibril. A possible mechanism is proposed: B3D forms a low-temperature oligomer, which is at least partially unfolded by heat and subsequently reassembles more slowly as a fibril. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim


Li H.,Jiangsu Food and Pharmaceutical Science College
Zhuzao/Foundry | Year: 2014

Casting precision and its stability has big influence on the allowance of the machining process after casting. On basis of statistics, mathematical model of objective profit function was built which uses the machining allowance as argument, with the casting precision and it's stability as known values. On the basis of integral principle, objective function is solved by way of computer programming, and then the optimal value of machining allowance and optimal profit margin is confirmed. The simulation indicates that besides the casting precision, casting stability also has big influence on the machining allowance and profit margin. The model has practical value and has reference value to the similar processing problems.


Lu T.-T.,Jiangsu food and pharmaceutical science College
Applied Mechanics and Materials | Year: 2014

According to the current situation of small and medium-sized library carried out feasibility analysis and the actual demand. The library's basic business processes are described. Combining with the knowledge of library and database technology to design each module. The system using the Windows XP/Windows 6.0 as system platform, using Visual basic 6.0 as a front-end application development tools, Microsoft SQL Server 2000 as the background database. Through to the small and medium-sized books management system management system requirements analysis, functional module division, database model analysis, designed the database structure and application. Due to the use of computer management, improved the traditional manual management way, improve the management level. © (2014) Trans Tech Publications, Switzerland.


Tang M.,Jiangsu Food and Pharmaceutical Science College
Advanced Materials Research | Year: 2014

According to the implementation approach of National University Student Physical Health Standard all college students have to carry out physical health standards and are tested annually. The test of college students physical health is a comprehensive assessment of college students' physical health status from the body shape, physical function, physical fitness and other aspects. Through studying and analyzing the test data of application of the physical health of college students,we know that we can learn the physical health of college students more objectively from the data and the data can also fully reflect the physical health of college students. It can specify the correct direction of the physical education and provide a valuable reference for the implementation of education reform. © (2014) Trans Tech Publications, Switzerland.


Yang X.G.,Jiangsu Food and Pharmaceutical Science College
Advanced Materials Research | Year: 2014

The enterprise practice of teachers in higher vocational colleges is adapt to the needs of the development of higher vocational education. It is an important approach to build "the double teacher" construction. Through researching the data that obtained from some higher vocational college teachers' enterprise practice, the paper has done some analysis on the current overall status of the teachers in enterprise practice. We have carried on some explorations about the existing problems in three areas: colleges and teachers and enterprises. © (2014) Trans Tech Publications, Switzerland.


Zhao J.,Jiangsu Food and Pharmaceutical Science College
MATEC Web of Conferences | Year: 2015

This method of prediction using the data mining to analyze huge amounts of data as a preferred tool has been widely used in various fields. In the midst of it, the routine traffic data exists in a large number of isolated data in real time without establishing relationships with other data, and detects the amount of data which is greater than that at present. The usage of these data which is relatively shallow requires an in-depth analysis of its data model. Therefore, this paper uses a fuzzy clustering analysis method of feature points to study the traffic flow, uses a Markov decision chain model to study traffic jams, uses quantitative sample points based on the information entropy to calculate traffic flow trends and uses a heuristic prediction model to predict the road con-gestion. Through the simulation experiment which verifies the correctness of the model, this research is to advance the development of the road and to provide a basis for a dredging plan. © Owned by the authors, published by EDP Sciences, 2015.


Li Y.,Jiangsu Food and Pharmaceutical Science College
Carpathian Journal of Food Science and Technology | Year: 2014

With the social progress and the improvement of people's living level, people have more and more opportunities to eat out and require more on the hotel food. Six sigma management is a set of systematic business improvement system. This paper analyzes the feasibility of six sigma management in hotel food safety control. The basic theory of six sigma management is described. The application of six sigma management in hotel food safety control is discussed. Its introduction in hotel food safety control aims to improve food quality and meet the demand of customers, thus to provides comments and suggestions for the establishment of safe and reliable food safety system.


Chen Y.,Jiangsu Food and Pharmaceutical Science College
Applied Mechanics and Materials | Year: 2014

Our country has entered the aging society ranks, the elderly tourism markets have great potential. Through the investigation and analysis of Huaian’s elderly tourism consumption behavior, this paper makes use of questionnaires and interview for the elderly tourists in Huaian city to study the consumer behavior; characteristics of this market. Some market development strategies have been put forward to help the travel agency design tourism products suitable for the elderly, improve tourist services for the elderly in quality, develop the tourism market for the elderly. © (2014) Trans Tech Publications, Switzerland.


Xu R.,Jiangsu Food and Pharmaceutical Science College
Advanced Materials Research | Year: 2014

Canal Heritage is an open complex giant system. Grand Canal protection project reflects our cultural heritage protection is "extended to dynamic, giant technology, linear technology and life functions, such as the direction of the trend." In this paper, as an entry point to the cultural heritage of the canal, the canal inscription focuses on a certain city community development and ecological protection combined to enhance urban livability, concepts and methods to achieve sustainable urban development. This paper defined that the culture heritage of the canal is an important opportunity to build an ecological city in the community, and then discusses the development of eco-city location, the relationship between urban spatial development strategy and coordinated development of the county cultural and heritage canals and canal protection development and implementation of water from the environment comprehensive renovation, remodel the natural environment, and create a living environment system, promote the development of cultural tourism, highlight various aspects of regional development prioritie. © (2014) Trans Tech Publications, Switzerland.


Ren Y.,Jiangsu Food and Pharmaceutical Science College
Advanced Materials Research | Year: 2014

Ecological tourism's development must be based on the eco-tourism resources. Building a reasonable and scientific evaluation model for the eco-tourism resources is good for the science of ecological tourism's development and the accuracy of the laws of nature and the sustainable development of human. Based on the traveling accommodation ecological footprint model and traveling transport ecological footprint model, the paper is to make a quantitative analysis of Huaian tourism sustainable development. It provides strategies of the management for tourism destination and provides theoretical basis for the future development planning and drafting corresponding policies. © (2014) Trans Tech Publications, Switzerland.

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