Tong F.,Nanjing University |
Tong F.,Suzhou Fifth Peoples Hospital |
Cao P.,Jiangsu Province Academy of Traditional Chinese Medicine |
Yin Y.,Jiang Nan University |
And 3 more authors.
Digestive Diseases and Sciences | Year: 2014
Gastric carcinogenesis represents a stepwise progression from chronic inflammation to invasive adenocarcinomas and distant metastasis. It has been widely accepted that these pathologic changes are contributed by aberrant activation or inactivation of protein-coding proto-oncogenes and tumor suppressor genes. However, recent discoveries in microRNA research have reshaped our understanding of the role of non-protein-coding genes in carcinogenesis. MicroRNAs (miRNAs) are a family of 18-25-nucleotide small RNAs that negatively regulate gene expression at the post-transcriptional level during various crucial cell processes such as apoptosis, differentiation and development. Changes in miRNA expression profiles have been observed in a variety of human tumors, including gastric cancer. Further studies demonstrated that miRNAs may function as tumor suppressors and oncogenes. These findings have shown great potential of miRNAs as a novel class of therapeutic targets. In addition, it was found that some miRNAs were directly involved in patients with gastric cancer, including prognosis prediction, treatment selection, and in the search for unknown primary sites. MiRNAs have also been proved to be detectable in serum and plasma. In this review, we summarize the function of miRNAs in gastric cancer. Furthermore, we describe the pathophysiological roles of these miRNAs and their clinical potential as diagnostic biomarkers and therapeutic targets. © 2013 Springer Science+Business Media New York.
Ren Z.,Jiang Nan University |
Zhang D.,Wuhan University of Technology |
Wang Z.,Wuhan University of Technology
Energy | Year: 2012
Proton exchange membrane fuel cell (PEMFC) is a potential alternative for the internal combustion engine. But many problems, such as metallic bipolar plate instead of graphite bipolar plate to decrease the cost, should be solved before its application. Based on the previous results that single cell with TiN/Ti as bipolar plates shows high performance and enough long-time durability, the progress on the stacks with TiN/Ti as bipolar plates is reported in this manuscript. Till now seldom report is focused on stacks because of the complicated processing technique, especially for that with TiN/Ti as bipolar plate. The flow field in the plate is punched from titanium deformation, and two plates are welded by laser welding to form one piece of bipolar plate. The adopted processing techniques for stacks with TiN/Ti as bipolar plate exhibit advantage and feasibility in industry. The power density by weight for the stack is as high as 1353 W kg-1, although it still has space to be improved. Next work should be focused on the design of flow channel parameters and flow field type based on plastic deformation of metal materials. © 2012 Elsevier Ltd.
Li X.L.,Jiang Nan University |
Jing H.,Jiang Nan University
Applied Mechanics and Materials | Year: 2013
In compounded film process, as the way of exchanging rollers manually in the end of unwinding rollers will lead to a decline in production efficiency, a multi-motor wheeled automatic roller exchanging system is proposed. The system drives four servo motors by Programmable Multiple-Axis Controller (PMAC) simultaneously, makes two servo motors which drive cross shaft and cutter shaft under high precision position control mode, makes the other two servo motors which drive unwinding rollers under speed control mode, detects the position of dancer roll to keep tension constant. Compared with the way of exchanging rollers manually, the new way can exchange rollers effectively with no downtime, improve the production efficiency and the rate of finished products. © (2013) Trans Tech Publications, Switzerland.
Liu C.,Jiang Nan University |
Hui J.,Jiang Nan University
Applied Mechanics and Materials | Year: 2013
Based on analyzing the development and the performance feature of existing solar tracker, we propose a solar Maximum Power Point Tracking (MPPT) strategy which combines photoelectric sensor and image processing. Firstly, photoelectric tracking mode positions the sun in the field of view of the image sensor. Then, the position of the sun image is captured by the image sensor. After that, we can find the coordinates of the sun spot in the field of view through image binarization processing. According to the number of steps of stepper motor rotation which is calculated by the deviation of coordinates, the controller drives the biaxial photosensitive (PV) array tracking device, making the sun spot always fall in the centre of the image. Tests show that the elevation angle and azimuth angle of the tracking range of the photovoltaic array are both 0~270°.The average tracking error of elevation angle is less than 0.7°, and the average tracking error of azimuth angle is less than 0.5°. © (2013) Trans Tech Publications, Switzerland.
Zhang S.,Jiang Nan University |
Yu A.,Jiang Nan University |
Liu S.,Jiang Nan University |
Zhao J.,Jiang Nan University |
And 2 more authors.
Polymer Bulletin | Year: 2012
UV-curable waterborne polyurethane (WUPU)/silica nanocomposites were prepared using various silica by phase-inversion emulsification method. TEM examinations of nanostructured films indicated that the organic modified nanosilica was well dispersed in the WUPU matrix, while the acid and alkaline silica formed much less compact, or densely aggregated structure. DMA analysis demonstrated that the WUPU/silica nanocomposite films had a broadening of the tand peak and shifted to higher temperature. The WUPU/silica nanocomposite films displayed enhanced storage modulus, Shore A hardness, tensile strength without sacrificing high elongation at break compared to that of the pure WUPU film. The resulting nanocomposite films are possibly interesting for the generation of waterborne UV-curable transparent coatings with scratch-resistance. © Springer-Verlag 2011.
Zhang S.,Jiang Nan University |
Renliu,Jiang Nan University |
Jiang J.,Jiang Nan University |
Yang C.,Jiang Nan University |
And 2 more authors.
Progress in Organic Coatings | Year: 2011
Waterborne UV-curable polyurethane (WUPU)/silica nanocomposites were prepared by in situ method using aqueous silica sol. SEM examinations of hybrid films indicated that the nanosilica were well dispersed in the matrix. Atomic force microscopy revealed that the microphase separation between polyurethane and silica was significantly affected by the amount of silica incorporated. DMA analysis showed that the nanocomposite films with silica nanoparticles showed a single tan δ peak, which implies that soft and hard segments of polyurethane are well phase mixed. The nanostructure films displayed enhanced storage modulus, tensile strength without sacrificing high elongation at break. The resulting transparent hybrid films are promising for a number of applications, e.g. for high performance water-based UV-curable coatings. © 2010 Elsevier B.V. All rights reserved.
Wu L.,Jiang Nan University |
Gao Y.Z.,Jiang Nan University
Advanced Materials Research | Year: 2014
Active power filter (APF) is a new power electronic device used for reactive power compensation and dynamic harmonic suppression. Its performance depends on the highly precise detection of harmonic and reactive current. In view of the low pass filter's defection in traditional ip-iq method, this paper proposes a wavelet filter based on wavelet analysis. This algorithm could attain higher detection precision with lower cost. The simulate results illustrate the efficiency and accuracy of it. © (2014) Trans Tech Publications, Switzerland.
Liu S.-C.,Jiang Nan University |
Liu Y.,Jiang Nan University
2016 IEEE/ACIS 17th International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing, SNPD 2016 | Year: 2016
The ever-increasing complexity of computer network and various new types of bugs make the network security become an ever-growing serious challenge. In the evaluation of network security risk, the cause-and-effect relationship between multiple attack steps can be described well in an attack graph model. However, its test result is uncertain. Focused on this issue, the method of fusing attack graph model and Hidden Markov model (HMM) was proposed. Firstly, the network environment and attacker's aggressive behavior were abstracted by the attack graph model; Secondly, the probabilistic mapping that was between network observation and attack status was established by the HMM; Finally, the Viterbi algorithm was used to calculate the maximum probability state transition sequence. Experimental results show that the maximum probability of the state transition sequence can be effectively calculated and then the attack intention can be accurately inferred by this dual model. This method provides a good configuration for network security administrators. © 2016 IEEE.
Xue X.,Jiang Nan University |
Shen Y.,Jiang Nan University |
Wu D.,Jiang Nan University
Chinese Control Conference, CCC | Year: 2012
For the node localization of wireless sensor network, the cost of anchor nodes is very high. To reduce it, this paper adopts the idea of virtual anchor nodes, introduces the Gauss Marco's mobile model to identify the movement trajectories of virtual anchor node, and then optimize it, so that the virtual anchor node can distribute uniformly in the region detected. Combining with the centroid localization algorithm, a high coverage rate, low energy consumption, low cost and fast localization algorithm can be achieved. The simulation results show that the technique proposed in this paper is effective, and the positioning error can meet most application requirements. © 2012 Chinese Assoc of Automati.
Sato R.,Jiang Nan University |
Sato R.,Osaka Electro-Communication University |
Guo W.,Osaka Electro-Communication University
MATEC Web of Conferences | Year: 2016
The importance of popular education in architectural heritage is well known. It is an effective method for public education to develop applications that utilize digital copy of architectural heritage. We provide a case study focusing on the historical buildings of Toji Temple in Kyoto, Japan. We digitize the historical buildings in both overall construction and detailed structures. We build a demonstration and operating system using multimedia technologies such as multimedia touch screen desk system. The system will produce 3D digital models of architectural heritage with high resolution and use advanced technology to develop a variety of demonstration applications that can enhance your presentation and ease operation. The users can also have more opportunities and ways to improve their interests in learning and understanding about the architectural heritage knowledge, hence finding new ways to further improve the methodology of architectural heritage education with the application of multimedia interactive technologies and digital copy of historical buildings. © 2016 The Authors, published by EDP Sciences.