Jaypee University of Information Technology

Solan, India

Jaypee University of Information Technology is a state university in Waknaghat, Solan, Himachal Pradesh, India. The curriculum focuses on undergraduate, postgraduate and doctoral level studies and research in engineering and applied science disciplines. Wikipedia.

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Durai R.S.R.,Jaypee University of Information Technology
Proceedings of 2016 International Symposium on Information Theory and Its Applications, ISITA 2016 | Year: 2016

This paper proposes a coding scheme that derives a multiple-rate code from existing channel codes defined over the composite field and the ground field, where code length is fixed. Formally, from codes C1(k, 1), C2 (k, 2),..., Ck(k, k) defined over GF(q) together with the code C(n,k) over GF(qn), the proposed scheme derives a multiple-rate code with fixed code length. The primary benefit of the proposed multiple-rate code is that it is equipped with a common encoding and decoding strategy. Identification of coded user messages of variable length are carried out through a simple procedure using orthogonal projectors. © 2016 IEICE.

Garlapati V.K.,Jaypee University of Information Technology
Renewable and Sustainable Energy Reviews | Year: 2016

Electronic waste or e-waste is one of the global rising problems in developing countries like India and developed countries. E-waste comprises material that is valuable as well as toxic and has shoddier health and environment impact. This review paper presents an overview of global e-waste stats, health concerns of e-waste components along with the waste management, recycling, legislative polices and recommendations related to e-waste. Existing and future initiatives of e-waste management have been addressed by explaining the developed countries initiatives towards e-waste management. The key to success in terms of e-waste management such as Extended Producer Responsibility (EPR) and Producer Responsibility Organization (PRO) initiatives have been presented in a lucid manner. E-waste arena is a platform for business initiative for energy production (hydrogen and electricity) and precise metal recovery (gold, silver and platinum) through biotechnological approaches. © 2015 Elsevier Ltd.

Singh G.,Jaypee University of Information Technology
Infrared Physics and Technology | Year: 2010

The effects of 2-D electromagnetic crystal substrate on the performance of a rectangular microstrip patch antennas at THz frequencies is simulated. Electromagnetic crystal substrate is used to obtain extremely broad-bandwidth with multi-frequency band operation of the proposed microstrip antennas. Multi-frequency band microstrip patch antennas are used in modern communication systems in order to enhance their capacity through frequency reuse. The simulated 10 dB impedance bandwidth of the rectangular patch microstrip antenna is 34.3% at THz frequency (0.6-0.95 THz). The radiation efficiency, gain and directivity of the proposed antenna are presented at different THz frequencies. The simulation has been performed using CST Microwave Studio, which is a commercially available electromagnetic simulator based on finite integral technique. © 2009 Elsevier B.V. All rights reserved.

Jain T.,Jaypee University of Information Technology
Communications in Computer and Information Science | Year: 2012

A wireless sensor network can be used to monitor the environment and warns for a mishappening occurring in future. The proposed sensor network protocol is hybrid and bi-directional. The dynamic cluster head formation increases the network life. Efficient data aggregation techniques are used so that the data transmission is energy efficient, with less aggregation overhead and is reliable. The concept of distributed computing is also applied so that the work of the sink node is made easy and fast. © 2012 Springer-Verlag.

Sehgal M.,Jaypee University of Information Technology | Singh T.R.,Jaypee University of Information Technology
DNA Repair | Year: 2014

We present DR-GAS. 11DNA Repair-Genetic Association Studies., a unique, consolidated and comprehensive DNA repair genetic association studies database of human DNA repair system. It presents information on repair genes, assorted mechanisms of DNA repair, linkage disequilibrium, haplotype blocks, nsSNPs, phosphorylation sites, associated diseases, and pathways involved in repair systems. DNA repair is an intricate process which plays an essential role in maintaining the integrity of the genome by eradicating the damaging effect of internal and external changes in the genome. Hence, it is crucial to extensively understand the intact process of DNA repair, genes involved, non-synonymous SNPs which perhaps affect the function, phosphorylated residues and other related genetic parameters. All the corresponding entries for DNA repair genes, such as proteins, OMIM IDs, literature references and pathways are cross-referenced to their respective primary databases. DNA repair genes and their associated parameters are either represented in tabular or in graphical form through images elucidated by computational and statistical analyses. It is believed that the database will assist molecular biologists, biotechnologists, therapeutic developers and other scientific community to encounter biologically meaningful information, and meticulous contribution of genetic level information towards treacherous diseases in human DNA repair systems. DR-GAS is freely available for academic and research purposes at: http://www.bioinfoindia.org/drgas. © 2014 Elsevier B.V.

Lohan S.,Jaypee University of Information Technology | Bisht G.S.,Jaypee University of Information Technology
Current Pharmaceutical Design | Year: 2013

Rapid increase in the emergence and spread of microbes resistant to conventionally used antibiotics has become a major threat to global health care. Antimicrobial peptides (AMPs) are considered as a potential source of novel antibiotics because of their numerous advantages such as broad-spectrum activity, lower tendency to induce resistance, immunomodulatory response and unique mode of action. However, AMPs have several drawbacks such as; susceptibility to protease degradation, toxicity and high costs of manufacturing. Therefore, extensive research efforts are underway to explore the therapeutic potential of these fascinating natural compounds. This review highlights the potential of small cationic antimicrobial peptidomimetics (SCAMPs; M.W. ≈ 700 Da) as new generation antibiotics. In particular, we focused on recently identified small active pharmacophore from bulky templates of native AMPs, β-peptides, and lipopeptides. In addition, various design strategies recently undertaken to improve the physicochemical properties (proteolytic stability & plasma protein binding) of small cationic peptides have also been discussed. © 2013 Bentham Science Publishers.

Jain S.,Jaypee University of Information Technology | Vashistt J.,Jaypee University of Information Technology | Changotra H.,Jaypee University of Information Technology
Vaccine | Year: 2014

Rotaviruses, a major cause of gastroenteritis in children worldwide accounts for around 0.5 million deaths annually. Owing to their segmented genome and frequently evolving capability, these display a wide variation in their genotypes. In addition to commonly circulating genotypes (G1, G2, G3, G4, G9, P[4] and P[8]), a number of infrequent genotypes are being continuously reported to infect humans. These viral strains exhibit variation from one geographical setting to another in their distribution. Though the introduction of vaccines (RotaTeq and Rotarix) proved to be very effective in declining rotavirus associated morbidity and mortality, the number of infections remained same. Unusual genotypes significantly contribute to the rotavirus associated diarrhoeal burden, may reduce the efficacy of the vaccines in use and hence vaccinated individuals may not be benefited. Vaccine introduction may bring about a notable impact on the distribution and prevalence of these viruses due to selection pressure. Moreover, there is a sudden emergence of G2 and G3 in Brazil and United States, respectively, during the years 2006-2008 post-vaccination introduction; G9 and G12 became predominant during the years 1986 through 1998 before the vaccine introduction and now are commonly prevalent strains; and disparity in the predominance of strains after introduction of vaccines and their natural fluctuations poses a vital question on the impact of vaccines on rotavirus strain circulation. This interplay between vaccines and rotavirus strains is yet to be explored, but it certainly enforces the need to continuously monitor these changes in strains prevalence in a particular region. Furthermore, these fluctuations should be considered while administration or development of a vaccine, if rotavirus associated mortality is ever to be controlled. © 2014 Elsevier Ltd.

Pradhan J.K.,Jaypee University of Information Technology | Kumar S.,Jaypee University of Information Technology
Environmental Science and Pollution Research | Year: 2014

Nowadays, e-waste is a major source of environmental problems and opportunities due to presence of hazardous elements and precious metals. This study was aimed to evaluate the pollution risk of heavy metal contamination by informal recycling of e-waste. Environmental risk assessment was determined using multivariate statistical analysis, index of geoaccumulation, enrichment factor, contamination factor, degree of contamination and pollution load index by analysing heavy metals in surface soils, plants and groundwater samples collected from and around informal recycling workshops in Mandoli industrial area, Delhi, India. Concentrations of heavy metals like As (17.08 mg/kg), Cd (1.29 mg/kg), Cu (115.50 mg/kg), Pb (2,645.31 mg/kg), Se (12.67 mg/kg) and Zn (776.84 mg/kg) were higher in surface soils of e-waste recycling areas compared to those in reference site. Level exceeded the values suggested by the US Environmental Protection Agency (EPA). High accumulations of heavy metals were also observed in the native plant samples (Cynodon dactylon) of e-waste recycling areas. The groundwater samples collected form recycling area had high heavy metal concentrations as compared to permissible limit of Indian Standards and maximum allowable limit of WHO guidelines for drinking water. Multivariate analysis and risk assessment studies based on total metal content explains the clear-cut differences among sampling sites and a strong evidence of heavy metal pollution because of informal recycling of e-waste. This study put forward that prolonged informal recycling of e-waste may accumulate high concentration of heavy metals in surface soils, plants and groundwater, which will be a matter of concern for both environmental and occupational hazards. This warrants an immediate need of remedial measures to reduce the heavy metal contamination of e-waste recycling sites. © 2014 Springer-Verlag Berlin Heidelberg.

Ramana J.,Jaypee University of Information Technology
BMC Research Notes | Year: 2012

Background: Renal cell carcinoma or RCC is one of the common and most lethal urological cancers, with 40% of the patients succumbing to death because of metastatic progression of the disease. Treatment of metastatic RCC remains highly challenging because of its resistance to chemotherapy as well as radiotherapy, besides surgical resection. Whereas RCC comprises tumors with differing histological types, clear cell RCC remains the most common. A major problem in the clinical management of patients presenting with localized ccRCC is the inability to determine tumor aggressiveness and accurately predict the risk of metastasis following surgery. As a measure to improve the diagnosis and prognosis of RCC, researchers have identified several molecular markers through a number of techniques. However the wealth of information available is scattered in literature and not easily amenable to data-mining. To reduce this gap, this work describes a comprehensive repository called Renal Cancer Gene Database, as an integrated gateway to study renal cancer related data. Findings: Renal Cancer Gene Database is a manually curated compendium of 240 protein-coding and 269 miRNA genes contributing to the etiology and pathogenesis of various forms of renal cell carcinomas. The protein coding genes have been classified according to the kind of gene alteration observed in RCC. RCDB also includes the miRNAsdysregulated in RCC, along with the corresponding information regarding the type of RCC and/or metastatic or prognostic significance. While some of the miRNA genes showed an association with other types of cancers few were unique to RCC. Users can query the database using keywords, category and chromosomal location of the genes. The knowledgebase can be freely accessed via a user-friendly web interface at http://www.juit.ac.in/attachments/jsr/rcdb/ homenew.html. Conclusions: It is hoped that this database would serve as a useful complement to the existing public resources and as a good starting point for researchers and physicians interested in RCC genetics. © 2012 Ramana; licensee BioMed Central Ltd.

Pradhan J.K.,Jaypee University of Information Technology | Kumar S.,Jaypee University of Information Technology
Waste Management and Research | Year: 2012

These days, electronic waste needs to be taken into consideration due to its materials content, but due to the heterogeneity of the metals present, reprocessing of electronic waste is quite limited. The bioleaching of metals from electronic waste was investigated by using cyanogenic bacterial strains (Chromobacterium violaceum, Pseudomonas aeruginosa and Pseudomonas fluorescens). A two-step bioleaching process was followed under cyanide-forming conditions for maximum metals mobilization. Both single and mixed cultures of cyanogenic bacteria were able to mobilize metals from electronic waste with different efficiencies. In all the flasks in which high metal mobilizations were observed, the consequent biomass productions were also high. Pseudomonas aeruginosa was applied in the bioleaching process for the first time and this achieved its bioleaching ability of mobilization of metals from electronic waste. Chromobacterium violaceum as a single culture and a mixture of C. violaceum and P. aeruginosa exhibited maximum metal mobilization. Chromobacterium violaceum was capable of leaching more than 79, 69, 46, 9 and 7% of Cu, Au, Zn, Fe and Ag, respectively at an electronic waste concentration of 1% w/v. Moreover, the mixture of C. violaceum and P. aeruginosa exhibited metals leaching of more than 83, 73, 49, 13 and 8% of total Cu, Au, Zn, Fe, and Ag, respectively. Precious metals were mobilized through bioleaching which might be considered as an industrial application for recycling of electronic waste in the near future. © The Author(s) 2012.

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