Rawlani S.,Sharad Pawar Dental College |
Singh A.L.,Jawaharlal Nehru Medical College and AVBR Hospital |
Bhowte R.,Sharad Pawar Dental College |
Degwekar S.,Sharad Pawar Dental College |
And 3 more authors.
Journal of Pakistan Association of Dermatologists | Year: 2012
Objective: To assess cutaneous and mucocutaneous lesions in leprosy patients taking multidrug therapy. Patients and methods: The present cross-sectional study was conducted after receiving approval from the ethical committee of the Datta Meghe institute of Medical Sciences University. The study population comprised of 30 admitted leprosy patients for taking multidrug treatment. All the patients were in-patients and residing at Leprosy Rehabilitation Center Worora for treatment. The written consent was taken from all the patients. The study was conducted over a period of 7 days. All the clinical findings observed in leprosy patients were recorded in pro forma containing separate column for each finding. The recorded data were tabulated and analyzed using chi square test and student t- test. Results: Patches were the most common type of cutaneous lesions (90%) observed in leprosy patients taking multi drug therapy, followed by ichthyosis/dryness of skin (60%), atrophy (26.75%), hair loss(20%) while only 13.4% patients showed papules and infiltrated lesions. There was multiple nerve involvement in patients taking multi drug therapy; out of that ulnar nerve is most commonly affected followed by radial nerve and post auricular nerve. Deformities found in these patients were in the form of claw hand (16.7%), lagophthalmos (13.4%), ulcer (6.7%) and absorption (3.3%). Conclusion: Early detection of leprosy cases not only helps in reduction of the transmission of Mycobacterium leprae, but also to reduce leprosy attributable disability and avoid complication from chronic infectious disease. Source