JASCO Corporation

Hachiōji, Japan

JASCO Corporation

Hachiōji, Japan
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Patent
Jasco Corporation and Jasco International Co. | Date: 2012-02-22

Measuring apparatus comprises a rotating plate 17, a torque detection plate 18 disposed on a same axis parallel to the plate 17 with a given gap, a torque sensor about the plate 18 through the specimen held between two plates. The plate 18 is a total reflection prism which is made from a material that has a greater refractive index than the specimen and transmits UV and infrared light. An ultraviolet beam is directed onto the specimen through the prism. An infrared beam is directed into the prism. The infrared beam emerging from the prism after total reflection from the interface between the prism and the specimen is detected. A signal processor analyzes the infrared absorption spectrum of the specimen on the basis of the infrared beam. While the viscosity of the specimen in the curing process is measured, the signal processor simultaneously measures the infrared absorption spectrum.


Saito M.,JASCO Corporation
Journal of Bioscience and Bioengineering | Year: 2013

In the early days of supercritical fluid chromatography (SFC), it was categorized as high-pressure or dense gas chromatography (HPGC or DGC) and low boiling point hydrocarbons were used as supercritical mobile phase. Various liquids and gases were examined, however, by the late 1970s, carbon dioxide (CO2) became the most preferred fluid because it has low critical temperature (31.1°C) and relatively low critical pressure (7.38 MPa); in addition, it is non-toxic, non-flammable and inexpensive. A prototype of a modern packed-column SFC instrument appeared in the late 1970s. However, in the 1980s, as open tubular capillary columns appeared and there was keen competition with packed columns. And packed-column SFC at once became less popular, but it regained popularity in the early 1990s. The history of SFC was of " the rise and fall." Advances in chiral stationary phase took place in the early 1990s made packed-column SFC truly useful chiral separation method and SFC is now regarded as an inevitable separation tool both in analytical and preparative separation. © 2012 The Society for Biotechnology, Japan.


Patent
Jasco Corporation | Date: 2012-08-02

The figure is fixed in a given position. If peaks are seen in the positive Y direction, the minimum value of the difference in height between the spectrum and the figure in the range where the figure is present on the X-axis. The minimum value and the height of the figure at the reference point are added. The figure is moved within a range containing the reference point, and the minimum value of the difference in height between the spectrum and the figure is added to the height of the figure at the reference point, at each point on the figure. A maximum value L_((xi) )of the calculated values is obtained, and the maximum value L_((xi) )is obtained as a baseline value at the X coordinate of the reference point.


A confocal microscopy apparatus (10) for irradiating a measuring region of a specimen with light and for obtaining spectral information of light from the measuring region, comprising: a specimen irradiation means (20); an objective lens (32); an imaging lens (34); an aperture stop (36) having a plurality of openings disposed on an imaging plane of the imaging lens; and spectrum obtaining means (50, 60) for detecting and for obtaining the spectral information of light passing through each of the openings. Therefore, the spectral information according to light passing through each opening maintains the same spatial resolution as that obtained with the aperture stop having a circular opening, and the spectral information of light from the plurality of points of the specimen can be obtained altogether. Consequently, distribution measurement of a given measuring region of the specimen can be executed with high resolution and at high speed.


A chromatography system has a multi-channel detection device including a flow cell, optics for directing light from light sources to the flow cell and outputting light that has passed through the flow cell, and a multi-channel detector. The optics has a function of dispersing light in wavelength in an optical path. The detector receives the light dispersed in wavelength. The multi-channel detection device also has a signal processing part connected to the detector. The chromatography system has a data processing apparatus. The signal processing circuit has a function of calculating an absorbance by absorbance=log_(10)(I/I_(0)) using the intensity I of light having a wavelength to be measured that is outputted from the detector and a reference intensity I_(0 )of light that is an average of intensities of light having different wavelengths that is produced at the same point of time as the light having a wavelength to be measured.


A high-pressure fluorescence flow cell comprises a cell body made of a light-transmissive material, wherein the cell body is penetrated by a straight-line flow path for a high-pressure fluid, wherein the flow path is formed with a cross section of 0.1 mm^(2 )to 5 mm^(2), both inclusive, orthogonal to its longitudinal direction, wherein the ratio t/d of the wall thickness t (mm) to the width d (mm) of the flow path satisfies formula (1) below, where indicates the tensile stress (MPa) of the material of the cell body, and P indicates the withstand pressure (MPa) of the cell body.


Patent
Jasco Corporation | Date: 2013-07-03

A depolarizer includes a pair of wedge-shaped plates made of an optically isotropic material, laid one on top of another such that the total thickness is constant and wedge-plate holding means for holding the pair of wedge plates separately. The wedge-plate holding means includes a pressure-applying section for applying pressure to each of the pair of wedge plates in a direction perpendicular to the thickness direction of the pair of wedge plates. The pressure-applying direction for one of the pair of wedge plates and the pressure-applying direction for the other of the pair of wedge plates intersect at an angle of 45 degrees.


A chromatography system has a multi-channel detection device 10 including a flow cell 12 to which a specimen is supplied, optics for directing light from light sources 11 to the flow cell 12 and outputting light that has passed through the flow cell, and a multi-channel detector 13 disposed on an output of the optics. The optics has a function of dispersing light in wavelength in an optical path. The detector 13 receives the light dispersed in wavelength. The multi-channel detection device 10 also has a signal processing part 14 connected to the detector. The chromatography system has a data processing apparatus 20. The signal processing circuit has a function of calculating an absorbance by absorbance = -log_(10)(I/I_(0)) using the intensity I of light having a wavelength to be measured that is outputted from the detector and a reference intensity I_(0) of light that is an average of intensities of light having different wavelengths that is produced at the same point of time as the light having a wavelength to be measured.


Patent
JASCO Corporation | Date: 2013-03-28

A circular dichroism (CD) spectrometer includes an alignment mechanism that automatically adjusts the elements thereof at appropriate positions. The spectrometer has a focusing-lens position-and-orientation adjustment mechanism which adjusts the position and the orientation of the detector-side focusing lens. It also has a detector rotation mechanism which adjusts the orientation of the detector. Firstly, a control PC monitors the CD spectrum of D form of optical enantiomers, and the adjustment mechanism adjusts the focusing lens such that the monitored CD spectrum matches the reference spectrum related to the D form. Next, the control PC moniters CD spectrum of L form of optical enantiomers, and the adjustment mechanism adjusts the focusing lens such that the monitored CD spectrum of the D and L forms become symmetrical. And, the rotation mechanism adjusts the orientation of the detector such that the intensity of the detector signal is maximized.


A high-pressure fluorescence flow cell comprises a cell body made of a light-transmissive material, wherein the cell body is penetrated by a straight-line flow path for a high-pressure fluid, wherein the flow path is formed with a cross section of 0.1 mm^(2) to 5 mm^(2), both inclusive, orthogonal to its longitudinal direction, wherein the ratio t/d of the wall thickness t (mm) to the width d (mm) of the flow path satisfies formula (1) below, where indicates the tensile stress (MPa) of the material of the cell body, and P indicates the withstand pressure (MPa) of the cell body.

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