Jardin Botanico Nacional Dr. Rafael Ma. Moscoso

Santo Domingo, Dominican Republic

Jardin Botanico Nacional Dr. Rafael Ma. Moscoso

Santo Domingo, Dominican Republic
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Vandebroek I.,New York Botanical Garden | Balick M.J.,New York Botanical Garden | Ososki A.,San Francisco Medical Center | Kronenberg F.,New York Botanical Garden | And 5 more authors.
Journal of Ethnopharmacology | Year: 2010

Ethnopharmacological relevance: Plant mixtures are understudied in ethnobotanical research. Aim of the study: To investigate the importance of plant mixtures (remedies consisting of at least two plants) in Dominican traditional medicine. Materials and methods: A Spanish language questionnaire was administered to 174 Dominicans living in New York City (NYC) and 145 Dominicans living in the Dominican Republic (DR), including lay persons (who self-medicate with plants) and specialists (traditional healers). Plants were identified through specimens purchased in NYC botánica shops and Latino grocery shops, and from voucher collections. Results: The percentage of mixtures as compared to single plants in plant use reports varied between 32 and 41%, depending on the geographic location (NYC or DR) and participant status (lay person or specialist). Respiratory conditions, reproductive health and genitourinary conditions were the main categories for which Dominicans use plant mixtures. Lay persons reported significantly more mixtures prepared as teas, mainly used in NYC to treat respiratory conditions. Specialists mentioned significantly more botellas (bottled herbal mixtures), used most frequently in the DR to treat reproductive health and genitourinary conditions. Cluster analysis demonstrated that different plant species are used to treat respiratory conditions as compared to reproductive health and genitourinary conditions. Interview participants believed that combining plants in mixtures increases their potency and versatility as medicines. Conclusions: The present study demonstrates the importance and complexity of plant mixtures in Dominican traditional medicine and the variation in its practices influenced by migration from the DR to NYC, shedding new light on the foundations of a particular ethnomedical system. © 2009 Elsevier Ireland Ltd.


PubMed | Jardin Botanico Nacional Dr. Rafael Ma. Moscoso, Institute of Jamaica, Federal University of Vales do Jequitinhonha and Mucuri, University of Sao Paulo and 13 more.
Type: | Journal: Molecular phylogenetics and evolution | Year: 2017

Myrteae (c. 2500 species; 51 genera) is the largest tribe of Myrtaceae and an ecologically important groups of angiosperms in the Neotropics. Systematic relationships in Myrteae are complex, hindering conservation initiatives and jeopardizing evolutionary modelling. A well-supported and robust phylogenetic hypothesis was here targeted towards a comprehensive understanding of the relationships within the tribe. The resultant topology was used as a base for key evolutionary analyses such as age estimation, historical biogeography and diversification rate patterns. One nuclear (ITS) and seven chloroplast (psbA-trnH, matK, ndhF, trnl-trnF, trnQ-rps16, rpl16 and rpl32-trnL) DNA regions for 115 taxa representing 46 out of the 51 genera in the tribe were accessed and analysed using maximum likelihood and Bayesian inference tools for phylogenetic reconstruction. Dates of diversification events were estimated and contrasted using two distinct fossil sets (macro and pollen) in BEAST. The subsequent dated phylogenies were compared and analysed for biogeographical patterns using BioGeoBEARS and diversification rates using BAMM. Myrteae phylogeny presents strong statistical support for three major clades within the tribe: Australasian group, Myrtus group and Main Neotropical Lineage. Dating results from calibration using macrofossil are an average of 20 million years older and show an early Paleocene origin of Myrteae, against a mid-Eocene one from the pollen fossil calibration. Biogeographic analysis shows the origin of Myrteae in Zealandia in both calibration approaches, followed by a widespread distribution throughout the still-linked Gondwana continents and diversification of Neotropical endemic lineages by later vicariance. Best configuration shift indicates three points of acceleration in diversification rates, all of them occurring in the Main Neotropical Lineage. Based on the reconstructed topology, several new taxonomic placements were recovered, including: the relative position of Myrtus communis, the placement of the Blepharocalyx group, the absence of generic endemism in the Caribbean, and the paraphyletism of the former Pimenta group. Distinct calibration approaches affect biogeography interpretation, increasing the number of necessary long distance dispersal events in the topology with older nodes. It is hypothesised that biological intrinsic factors such as modifications of embryo type and polyploidy might have played a role in accelerating shifts of diversification rates in Neotropical lineages. Future perspectives include formal subtribal classification, standardization of fossil calibration approaches and better links between diversification shifts and trait evolution.


Garcia R.,Jardin Botanico Nacional dr. Rafael Ma. Moscoso | Clase T.,Jardin Botanico Nacional dr. Rafael Ma. Moscoso | Seigler D.S.,Urbana University | Ebinger J.E.,Eastern Illinois University
Novon | Year: 2014

Vachellia azuana R. G. Garciá, Clase, Ebinger and Seigler (Fabaceae: Mimosoideae), a new species from the Azua Province, Dominican Republic, is described, illustrated, and compared to related species from the Dominican Republic and Haiti. This previously undescribed species is most similar to, but distinct from, V. barahonensis (Urb. and Ekman) Seigler and Ebinger, also known from Azua Province.


Skean Jr. J.D.,Albion College | Judd W.S.,University of Florida | Clase T.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Peguero B.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso
Brittonia | Year: 2010

Calycogonium bairdianum, a new species, is here described from the Cordillera Central of the Dominican Republic. It is compared to C. impressum, to which it is likely related. Although Calycogonium is not monophyletic, C. bairdianum and C. impressum may be related to other species in the genus that exhibit acarodomatia formed by hairs at the two major vein junctions on the leaf abaxial surface, a likely synapomorphy. Calycogonium bairdianum is distinguished from C. impressum by its relatively glabrous (vs. pubescent) and larger leaves (i.e., usually [2.9-]4.5-8.1 cm vs. 2.1-3.7 cm long) with veins that are plane to only slightly impressed adaxially (vs. more strongly impressed). © 2010 The New York Botanical Garden.


Ren Y.,Ohio State University | Acuna U.M.,Ohio State University | Jimenez F.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Garcia R.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | And 7 more authors.
Tetrahedron | Year: 2012

Six new (1-6) and eight known germacranolide-type sesquiterpene lactones, along with several known phenylpropanol coumarates and methylated flavonoids, were isolated from the leaves of Piptocoma rufescens, collected in the Dominican Republic. The new compounds were identified by analysis of their spectroscopic data, with the molecular structure of 3 being established by single-crystal X-ray diffraction. The absolute configurations of the sesquiterpene lactones isolated were determined from their CD and NOESY NMR spectra, together with the analysis of Mosher ester reactions. Bioassay screening results showed the majority of the sesquiterpene lactones isolated (1-13) to be highly cytotoxic toward the HT-29 human colon cancer cell line, with the most potent compound being 15-deoxygoyazensolide (10, IC 50, 0.26 μM). In addition, several of the sesquiterpene lactones exhibited NF-κB (p65) inhibitory activity. © 2012 Elsevier Ltd. All rights reserved.


Ren Y.,Ohio State University | Jimenez F.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Garcia R.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Mejia M.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | And 4 more authors.
Tetrahedron Letters | Year: 2013

A new sesquiterpene lactone, rufescenolide C (1), the first furanoheliangolide dimer, was isolated from the leaves of Piptocoma rufescens, collected in the Dominican Republic. Its structure was determined by interpretation of its spectroscopic data, with the absolute configuration being established by analysis of the CD spectrum. A plausible biogenesis of this dimer is proposed. This compound showed potent cytotoxicity with an IC50 value of 150 nM, when tested against HT-29 human colon cancer cells. © 2013 Elsevier Ltd. All rights reserved.

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