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Santo Domingo, Dominican Republic

Skean Jr. J.D.,Albion College | Judd W.S.,University of Florida | Clase T.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Peguero B.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso
Brittonia | Year: 2010

Calycogonium bairdianum, a new species, is here described from the Cordillera Central of the Dominican Republic. It is compared to C. impressum, to which it is likely related. Although Calycogonium is not monophyletic, C. bairdianum and C. impressum may be related to other species in the genus that exhibit acarodomatia formed by hairs at the two major vein junctions on the leaf abaxial surface, a likely synapomorphy. Calycogonium bairdianum is distinguished from C. impressum by its relatively glabrous (vs. pubescent) and larger leaves (i.e., usually [2.9-]4.5-8.1 cm vs. 2.1-3.7 cm long) with veins that are plane to only slightly impressed adaxially (vs. more strongly impressed). © 2010 The New York Botanical Garden. Source


Garcia R.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Clase T.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Seigler D.S.,Urbana University | Ebinger J.E.,Eastern Illinois University
Novon | Year: 2014

Vachellia azuana R. G. Garciá, Clase, Ebinger and Seigler (Fabaceae: Mimosoideae), a new species from the Azua Province, Dominican Republic, is described, illustrated, and compared to related species from the Dominican Republic and Haiti. This previously undescribed species is most similar to, but distinct from, V. barahonensis (Urb. and Ekman) Seigler and Ebinger, also known from Azua Province. Source


Ren Y.,Ohio State University | Jimenez F.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Garcia R.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Mejia M.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | And 4 more authors.
Tetrahedron Letters | Year: 2013

A new sesquiterpene lactone, rufescenolide C (1), the first furanoheliangolide dimer, was isolated from the leaves of Piptocoma rufescens, collected in the Dominican Republic. Its structure was determined by interpretation of its spectroscopic data, with the absolute configuration being established by analysis of the CD spectrum. A plausible biogenesis of this dimer is proposed. This compound showed potent cytotoxicity with an IC50 value of 150 nM, when tested against HT-29 human colon cancer cells. © 2013 Elsevier Ltd. All rights reserved. Source


Ren Y.,Ohio State University | Acuna U.M.,Ohio State University | Jimenez F.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | Garcia R.,Jardin Botanico Nacional Dr. Rafael Ma. Moscoso | And 7 more authors.
Tetrahedron | Year: 2012

Six new (1-6) and eight known germacranolide-type sesquiterpene lactones, along with several known phenylpropanol coumarates and methylated flavonoids, were isolated from the leaves of Piptocoma rufescens, collected in the Dominican Republic. The new compounds were identified by analysis of their spectroscopic data, with the molecular structure of 3 being established by single-crystal X-ray diffraction. The absolute configurations of the sesquiterpene lactones isolated were determined from their CD and NOESY NMR spectra, together with the analysis of Mosher ester reactions. Bioassay screening results showed the majority of the sesquiterpene lactones isolated (1-13) to be highly cytotoxic toward the HT-29 human colon cancer cell line, with the most potent compound being 15-deoxygoyazensolide (10, IC 50, 0.26 μM). In addition, several of the sesquiterpene lactones exhibited NF-κB (p65) inhibitory activity. © 2012 Elsevier Ltd. All rights reserved. Source

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