Japan Tobacco Inc. | Date: 2015-12-01
The present invention provides a tobacco raw material having a good smoking flavor and a method for producing the same. Provided is a tobacco raw material having a ratio, which is expressed as water-extracted material weight/hexane-extracted material weight, between the weight of an extracted material obtained by extraction using n-hexane as a solvent and the weight of an extracted material obtained following the extraction by further extraction using water as a solvent, of 0 or more and 1.5 or less.
Japan Tobacco Inc. | Date: 2015-01-09
Provision of a stabilized crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (compound A). A crystal of compound A, which shows a particular X-ray powder diffraction pattern of a characteristic diffraction peaks at diffraction angles 2() as measured by X-ray powder diffractometry.
Japan Tobacco Inc. | Date: 2015-03-18
The present invention provides a modified biotin-binding protein comprising an amino acid sequence represented by SEQ ID NO: 2 or its modified sequence and having a biotin-binding activity and replacement selected from the group consisting of:
Japan Tobacco Inc. | Date: 2015-01-28
A measuring apparatus for performing a basis weight measuring method for sheet tobacco according to the present invention includes: a light source (
Japan Tobacco Inc. | Date: 2015-02-19
Provided is a compound having an mPGES-1 inhibitory activity and useful for the prophylaxis or treatment of pain, rheumatism, osteoarthritis, fever, Alzheimers disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinal disease, systemic scleroderma and cancer including colorectal cancer. A compound represented by the formula [I] or a pharmaceutically acceptable salt thereof: wherein each symbol is as defined in the SPECIFICATION.