Toshiba Corporation and Japan National Institute of Radiological Sciences | Date: 2013-05-01
In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a magnet that is a seamless structure generates a static magnetic field in a bore having a cylindrical shape. First detectors and second detectors are each formed in a ring shape and detect gamma rays emitted from positron emitting radionuclides injected into a subject. The first detectors and the second detectors are disposed with a space therebetween in an axial direction of the bore so as to interpose the magnetic field center of the static magnetic field therebetween.
Japan National Institute of Radiological Sciences | Date: 2013-01-12
A radioactive substance detection device that detects a radioactive substance being present in a specified direction. A radiation detection element having a thickness that stops and detects a characteristic X-ray arriving from a radioactive substance being present in the specified direction that radiates both gamma rays and the characteristic X-rays, and allows the gamma ray arriving from the radioactive substance to pass through. A screening body having a thickness that screens out characteristic X-rays of radiation which arrives from directions other than the specified direction and allows gamma rays of radiation which arrives from directions other than the specified direction to pass through.
Japan National Institute of Radiological Sciences | Date: 2014-09-24
A helmet-type PET device includes a helmet portion (hemispherical detector) and an added portion (jaw portion detector, an ear portion detector, or a neck portion detector). The helmet portion includes a PET detector so as to cover a parietal region of an examination target. The added portion is positioned to dispose a PET detector at a part other than the parietal region of the examination target. PET measurement is performed using both an output from the PET detector at the helmet portion and an output from the PET detector at the added portion.
Japan National Institute of Radiological Sciences and Shimadzu Corporation | Date: 2013-03-28
When an image for PET attenuation correction is generated from an MR image, the MR image captured by MRI is segmented into regions according to pixel values. In a region in which a radiation attenuation coefficient is considered to be uniform, a radiation attenuation correction value is determined by referring to an existing radiation attenuation correction value table. In a region including multiple tissues having different radiation attenuation coefficients, a radiation attenuation correction value is determined by referring to a standard image. In such a manner, an image for PET attenuation correction in which tissues having similar pixel values in the MR image but different attenuation coefficients for radiation can be distinguished and that can accommodate individual differences and an affected area such as a space occupying lesion (for example, a cancer, abscess, or the like) and an organic defect is generated.
Japan National Institute of Radiological Sciences and Kyoto University | Date: 2014-12-30
This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a secretion signal sequence, wherein the vaccine is capable of inducing an antibody against an (optionally phospholylated) tau protein in a subject in a more sustained manner compared with a case where the mutant tau protein is administered directly.