Townsville, Australia

James Cook University
Townsville, Australia

James Cook University is a public university and is the second oldest university in Queensland, Australia. JCU is a teaching and research institution. The University's main campuses are located in the tropical cities of Cairns, Singapore and Townsville. JCU also has study centres in Mount Isa, Mackay and Thursday Island. A Brisbane campus, operated by Russo Higher Education, delivers undergraduate and postgraduate courses to international students. The University’s main fields of research include marine science, biodiversity, sustainable management of tropical ecosystems, genetics and genomics, tropical health care and tourism. Wikipedia.

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News Article | September 11, 2017

James Cook University (JCU), a globally-ranked university with approximately 22,000 students and two campuses in northern Queensland, Australia and a campus in Singapore, has chosen Keypath Education as its online program management (OPM) partner. JCU is ranked in the top 2% of universities worldwide. The ten-year partnership between JCU and Keypath will entail relaunching an existing Master of Nursing online program, as well as launching a Master of Data Science program in the online accelerated format. Courses commence for these two programs on October 30, 2017. The partnership will support a growing portfolio of online programs over the next several years. Keypath will provide their complete suite of online program management services, including market research, funding, course design, student recruitment, marketing, and student retention and success services. The goals of the partnership are to grow JCU market share in new and existing markets through the expansion of online degree programs. “We needed an online enablement partner with deep expertise in our region to successfully launch new programs and capitalize on emerging markets. Keypath has demonstrated both, and embedded with our staff for a unique and consultative relationship,” said James Cook University Senior Deputy Vice Chancellor, Professor Chris Cocklin. Keypath Education CEO Steve Fireng said, “James Cook University has incredible potential to attract not only domestic students but over time expand to recruit international students increasingly looking beyond their own borders to further their education online. Our partnership ensures JCU has in-demand programs, recruitment strategies and student support services necessary to grow their enrollment at home and abroad, backed by a diverse team dedicated to academic excellence and world-class distance learning experiences.” For more information about the James Cook University-Keypath partnership and online program management services, please contact Chris Williams, director of marketing, at chris.williams@keypathedu(dot)com or 847.616.8167. About James Cook University One of the world's leading institutions focusing on the tropics, Australia's James Cook University is surrounded by the spectacular ecosystems of the rainforests of the Wet tropics, the dry savannahs, and the iconic Great Barrier Reef. Its unique location enables students from Australia and overseas to study in a diverse physical environment unparalleled by any university in the world. Ranked in the top 2% of the world's tertiary institutions, James Cook University is dedicated to creating a brighter future for life in the tropics world-wide, through graduates and discoveries that make a difference. Learn more at About Keypath Education Keypath Education is dedicated to creating global access to high-quality online education by partnering with the world’s best universities to launch and grow high-quality degree programs via its online program management (OPM) division. Through OPM partnerships, Keypath acts as an extension of the university’s team, keeping its brand and academic rigor intact while accelerating the growth and quality of the university program portfolio. Services provided include market research, capital investment, program development, marketing, student recruitment, retention and course development. The company has offices and partners in the United States, Canada, the U.K. and Australia. Learn more at

Berzins S.P.,University of Melbourne | Smyth M.J.,Peter MacCallum Cancer Center | Baxter A.G.,James Cook University
Nature Reviews Immunology | Year: 2011

Natural killer T (NKT) cells are important regulatory lymphocytes that have been shown in mouse studies, to have a crucial role in promoting immunity to tumours, bacteria and viruses, and in suppressing cell-mediated autoimmunity. Many clinical studies have indicated that NKT cell deficiencies and functional defects might also contribute to similar human diseases, although there is no real consensus about the nature of the NKT cell defects or whether NKT cells could be important for the diagnosis and/or treatment of these conditions. In this Review, we describe the approaches that have been used to analyse the NKT cell populations of various patient groups, suggest new strategies to determine how (or indeed, if) NKT cell defects contribute to human disease, and discuss the prospects for using NKT cells for therapeutic benefit. © 2011 Macmillan Publishers Limited. All rights reserved.

Stuart M.J.,James Cook University | Baune B.T.,University of Adelaide
Neuroscience and Biobehavioral Reviews | Year: 2012

Unipolar depression and diabetes mellitus each account for a significant proportion of the global burden of disease. Epidemiological literature suggests a bi-directional relationship between these two common disorders, and evidence from the molecular sciences supports a role for inflammation in the pathogenesis and pathophysiology of each disorder individually. Recent advances in understanding the neurobiology of depression have implicated dysfunction of the hypothalamus-pituitary-adrenal axis, neurotrophins, and inflammatory mediators in the development of this disorder. Similarly, dysregulated facets of both the innate and adaptive immune system have been implicated in the onset of insulin resistance and type 2 diabetes. This review draws upon an emerging body of epidemiological and mechanistic evidence to support the hypothesis that shared inflammatory mechanisms may represent a key biological link in this co-morbidity. Given the shared mechanisms of this co-morbidity, these patients may be excellent candidates for novel immune targeted pharmacotherapy. © 2011 Elsevier Ltd.

Fiddick L.,James Cook University
Neuroscience and Biobehavioral Reviews | Year: 2011

Fear conditioning with its neurological basis in the amygdala and associated structures provides an important model of anxiety disorders. However, this review will argue for a distinction between fear-provoking immediate and anxiety-provoking potential threats, with the amygdala processing immediate threats and the cingulate cortex (and insular) processing potential threats. Four independent but related literatures are reviewed to bolster this argument: (1) rodent remote contextual fear conditioning, (2) symptom provocation in obsessive compulsive disorder (OCD), (3) fMRI investigations of risk assessment, and (4) behavioural and neurological studies of precautionary reasoning. These four literatures converge in suggesting that the cingulate cortex (and in more specific instances the insula) underlie potential threat assessment, providing support for a number of recent models posting the existence of a separate potential threat system that is dysfunctional in obsessive compulsive disorder (e.g., Szechtman and Woody, 2004; Woody and Szechtman, 2011). © 2011.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC1-PM-06-2016 | Award Amount: 23.70M | Year: 2017

A highly effective malaria vaccine against Plasmodium falciparum should help prevent half a million deaths from malaria each year. New vaccine technologies and antigen discovery approaches now make accelerated design and development of a highly effective multi-antigen multi-stage subunit vaccine feasible. Leading malariologists, vaccine researchers and product developers will here collaborate in an exciting programme of antigen discovery science linked to rapid clinical development of new vaccine candidates. Our approach tackles the toughest problems in malaria vaccine design: choice of the best antigens, attaining high immunogenicity, avoiding polymorphic antigens and increasing the durability of vaccine immunogenicity and efficacy. We take advantage of several recent advances in vaccinology and adopt some very new technologies: sequencing malaria peptides eluted from the HLA molecules, parasites expressing multiple transgenes, multi-antigen virus-like particles constructed with new bonding technologies, delayed release microcapsules, and liver-targeted immunisation with vaccine vectors. We enhance our chances of success by using a multi-stage multi-antigen approach, by optimising the magnitude and durability of well-characterised immune responses to key antigens, and using stringent infectious challenges and functional assays as established criteria for progression at each stage. The consortium comprises many of the foremost researchers in this field in Europe with leading groups in the USA, Australia and Africa. We link to EDCTP programmes and harmonise our timeline to fit with the recent roadmaps for malaria vaccine development. We include a major pharma partner and several excellent European biotech companies helping enhance Europes leading position in the commercial development of vaccines. This ambitious and exciting programme should have a high chance of success in tackling the major global health problem posed by malaria.

Pike D.A.,James Cook University
Global Ecology and Biogeography | Year: 2013

To understand whether climate limits current sea turtle nesting distributions and shapes the ecological niche of the terrestrial life-history stage of these wide-ranging marine vertebrates. Location: Coastlines world-wide. Methods: I predicted the spatial distributions of nesting habitat under current climatic conditions for seven sea turtle species using information criteria and maximum entropy modelling. I also compared niche similarity among species using three niche metrics: I, Schoener's D and relative rank. Results: Sea turtles currently nest across their entire bioclimatic envelopes, with up to six species predicted to nest on a single beach. The Caribbean Sea, Gulf of Mexico and Australasia support high nesting diversity, with most regional areas supporting three to five species. Despite large overlap in nesting distributions among species, loggerhead and green turtles have the broadest environmental niches, while Kemp's ridley and flatback turtles have very narrow niches. Main conclusions: The terrestrial nesting habitat of sea turtles is characterized by distinct climatic conditions, which are linked to the physical conditions necessary for eggs to hatch successfully and allow hatchlings to disperse from natal areas. Despite broad geographic patterns of overlap and similar embryonic tolerances to temperature and moisture among species, sea turtles partition habitat by nesting in different niche spaces. The tight link between current geographic patterns of nesting and climate, along with the dependence of developing embryos on nest microclimate, imply that regional or global changes in environmental conditions could differentially influence the distribution of sea turtle species under climate change. This could influence the adaptive potential of different populations, and predicting these responses before they occur will be important in mitigating the effects of climate change. © 2013 Blackwell Publishing Ltd.

Laurance W.F.,James Cook University
Trends in Ecology and Evolution | Year: 2013

Although many protected areas are foci for scientific research, they also face growing threats from illegal encroachment and overharvesting. Does the presence of field researchers help to limit such threats? Although evidence is largely anecdotal, researchers do appear to provide some protective effects, both actively (such as by deterring poachers) and passively (such as by benefiting local communities economically and thereby generating support for protected areas). However, much remains unknown about the generality and impacts of such benefits. A key priority is to develop a better understanding of the advantages and limitations of field research for aiding protected areas and their biodiversity. © 2013 Elsevier Ltd.

Phillips B.L.,James Cook University
Proceedings. Biological sciences / The Royal Society | Year: 2013

The virulence of a pathogen can vary strongly through time. While cyclical variation in virulence is regularly observed, directional shifts in virulence are less commonly observed and are typically associated with decreasing virulence of biological control agents through coevolution. It is increasingly appreciated, however, that spatial effects can lead to evolutionary trajectories that differ from standard expectations. One such possibility is that, as a pathogen spreads through a naive host population, its virulence increases on the invasion front. In Central America, there is compelling evidence for the recent spread of pathogenic Batrachochytrium dendrobatidis (Bd) and for its strong impact on amphibian populations. Here, we re-examine data on Bd prevalence and amphibian population decline across 13 sites from southern Mexico through Central America, and show that, in the initial phases of the Bd invasion, amphibian population decline lagged approximately 9 years behind the arrival of the pathogen, but that this lag diminished markedly over time. In total, our analysis suggests an increase in Bd virulence as it spread southwards, a pattern consistent with rapid evolution of increased virulence on Bd's invading front. The impact of Bd on amphibians might therefore be driven by rapid evolution in addition to more proximate environmental drivers.

Bellwood D.R.,James Cook University
Proceedings. Biological sciences / The Royal Society | Year: 2014

The evolution of ecological processes on coral reefs was examined based on Eocene fossil fishes from Monte Bolca, Italy and extant species from the Great Barrier Reef, Australia. Using ecologically relevant morphological metrics, we investigated the evolution of herbivory in surgeonfishes (Acanthuridae) and rabbitfishes (Siganidae). Eocene and Recent surgeonfishes showed remarkable similarities, with grazers, browsers and even specialized, long-snouted forms having Eocene analogues. These long-snouted Eocene species were probably pair-forming, crevice-feeding forms like their Recent counterparts. Although Eocene surgeonfishes likely played a critical role as herbivores during the origins of modern coral reefs, they lacked the novel morphologies seen in modern Acanthurus and Siganus (including eyes positioned high above their low-set mouths). Today, these forms dominate coral reefs in both abundance and species richness and are associated with feeding on shallow, exposed algal turfs. The radiation of these new forms, and their expansion into new habitats in the Oligocene-Miocene, reflects the second phase in the development of fish herbivory on coral reefs that is closely associated with the exploitation of highly productive short algal turfs.

Pike D.A.,James Cook University
Global Change Biology | Year: 2014

Animals living in tropical regions may be at increased risk from climate change because current temperatures at these locations already approach critical physiological thresholds. Relatively small temperature increases could cause animals to exceed these thresholds more often, resulting in substantial fitness costs or even death. Oviparous species could be especially vulnerable because the maximum thermal tolerances of incubating embryos is often lower than adult counterparts, and in many species mothers abandon the eggs after oviposition, rendering them immobile and thus unable to avoid extreme temperatures. As a consequence, the effects of climate change might become evident earlier and be more devastating for hatchling production in the tropics. Loggerhead sea turtles (Caretta caretta) have the widest nesting range of any living reptile, spanning temperate to tropical latitudes in both hemispheres. Currently, loggerhead sea turtle populations in the tropics produce nearly 30% fewer hatchlings per nest than temperate populations. Strong correlations between empirical hatching success and habitat quality allowed global predictions of the spatiotemporal impacts of climate change on this fitness trait. Under climate change, many sea turtle populations nesting in tropical environments are predicted to experience severe reductions in hatchling production, whereas hatching success in many temperate populations could remain unchanged or even increase with rising temperatures. Some populations could show very complex responses to climate change, with higher relative hatchling production as temperatures begin to increase, followed by declines as critical physiological thresholds are exceeded more frequently. Predicting when, where, and how climate change could impact the reproductive output of local populations is crucial for anticipating how a warming world will influence population size, growth, and stability. © 2013 John Wiley & Sons Ltd.

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