Singh R.,Jaipur National University |
Singh A.,Jaipur National University
Journal of the Iranian Chemical Society | Year: 2017
Abstract: An efficient synthesis of novel trispiropyrrolidine/thiapyrrolizidines has been reported by the 1,3-dipolar cycloaddition reaction of azomethine ylides with a novel dipolarophile 8,10-bis[(E)arylidene]-3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-one using deep eutectic solvent (DES). The DES is cheaper, biodegradable, non-toxic, recyclable and serves as dual role of catalyst as well as solvent. The suitable azomethine ylides were generated ‘in situ’ from the reaction of substituted isatin/acenaphthenequinone and sarcosine/1,3-thiazolane-4-carboxylic acid. In this protocol generation of one new five-membered pyrrolidine ring with three contiguous stereocenters occurred in a single operation. The stereochemistry of the synthesized compounds including regio- and diastereo was confirmed by spectroscopic techniques and single-crystal X-ray of one representative compound. Graphical Abstract: [Figure not available: see fulltext.] © 2017, Iranian Chemical Society.
Gupta P.,Banasthali University |
Ravi I.,Jaipur National University |
Sharma V.,Banasthali University
Journal of Plant Interactions | Year: 2013
Plants have developed many mechanisms to protect themselves against most potential microbial pathogens and diseases. Pathogenesis-related proteins are produced as a part of the active defenses to prevent attack. In this study, the induction of PR proteins in Eruca sativa in response to fungal pathogen Alternaria brassicicola was investigated in 10 days and one-month-old plants. Induction of pathogen resulted in a much marked increase in the activities of β-1,3-glucanase and chitinase in resistant cultivar (RTM-2002) as compared to susceptible (T-27) one. The enzyme activity gradually increased throughout the experimental period of 168 h compare to control. However, the activation of β-1,3-glucanase and chitinase was more rapid and to a greater extent in plants of RTM-2002 than in T-27. western blot analysis revealed the presence of 33 and 32 kDa β-1,3-glucanase and chitinase in induced arugula plants, respectively. The biochemical approach described in this article with E. sativa provide the basis for further efforts concentrating on the isolation and characterization of elements involved in perception and in the early steps of intracellular signal transduction. © 2013 Copyright Taylor and Francis Group, LLC.
Siddiqui K.M.,Jaipur National University |
Giri V.K.,Mmm Engineering College
2012 International Conference on Computing, Electronics and Electrical Technologies, ICCEET 2012 | Year: 2012
The Fast Fourier Transform (FFT) method is successfully used for the broken rotor bar fault detection purpose in the induction machines. It is based on the common-steady state analysis of the motor. This method is successfully used with Motor Current Signature Analysis (MCSA) technique for last three decades. However, this method is suffered from some serious drawbacks such as; it is applicable only in the constant load condition not for the variable load. The frequency-domain methods which are commonly used need accurate slip estimation for frequency components localization in any spectrum. It is also not suitable at the no-load or light load condition of the motor. At light load condition, it is quite difficult to distinguish between healthy and faulty rotors because the characteristic of broken rotor bar fault frequencies are very close to fundamental component and their amplitude are small in comparison. As a result, detection of the fault and classification of the fault severity under light load is almost impossible. In order to overcome the above problems of the FFT based technique, the Short Time Fourier Transform (STFT) Method was proposed. The excellent feature of this method is that it is capable to diagnose broken rotor bar fault in the transient condition. The STFT method also suffered from the drawback that it shows the constant window for all the frequencies. Therefore, it shows poor frequency resolution. In order to overcome all the problems stated so far, the most recent powerful mathematical tool i.e. Wavelet Transform (WT) has been used in the rotor broken bar fault detection purpose at all loading conditions. It shows variable window size for all the frequencies. Therefore, the WT method does not have resolution problem due to its multiresolution feature. This paper investigates the detection of rotor faults in induction machines by analyzing the starting current using a newly developed quantification technique based on the wavelet transform. The technique applies the wavelet transform to the envelope of the starting current. The envelope extraction is used to remove the strong fundamental component, which overshadows the characteristic differences between a healthy motor and a faulty motor with broken rotor bars. © 2012 IEEE.
Tiwari K.,Jaipur National University
Pakistan Journal of Biological Sciences | Year: 2013
The present study discusses the frequency distribution and genetic diversity of novel fungal endopyte Alternaria alternata within the Pongammia pinnata plant samples. A total of ten plant samples of Pongammia pinnata, Pierre. (Karanja) were collected from specific locations of Sanganer region of Rajasthan for the isolation of fungal endophytes. Of these, maximum frequency of Alternaria alternata (22.29%) were recorded which are morphologically similar but ecologically variant. Efficacy of randomly amplified polymorphic DNA (RAPD), were assessed in seventeen individuals of the primers was GCC 180 where as 10 bands were generated by GCC 181. The similarity coefficient matrix generated for the primers was subjected to algorithm UPGMA (Unweighted Pair Group Method Analysis) and clusters were generated using NTSYS 2.02 pc program. To stabilize the level of relatedness among the seventeen ecologically variant Alternaria alternata accessions, the dendrogram was constructed, which showed that all the isolates were diversified endophytically with in the plant Pongamia pinnata. © 2013 Asian Network for Scientific Information.
Kumar P.,Jaipur National University
Journal of Applied Pharmaceutical Science | Year: 2011
Acquired immune deficiency syndrome, a disease in which there is a severe loss of the body's cellular immunity, greatly lowering the resistance to infection and malignancy. The cause is a human immune deficiency virus, or HIV transmitted in blood and in sexual fluids. AIDS was first reported June 5, 1981. A co mbination of several antiretroviral drugs, called highly active antiretroviral therapy (HAART), has been very effective in reducing the number of HIV particles in the bloodstream. The best treatment for AIDS in humans is prevention by vaccination.
Sharma K.K.,Malaviya National Institute of Technology, Jaipur |
Sharma S.,Jaipur National University
Journal of Optics | Year: 2012
The problem of signal reconstruction using the samples of a signal f(t) and/or signals related to f(t) has been widely investigated in the literature. However, none of the existing sampling expansions deals with the signal reconstruction in the linear canonical transform (LCT) domain using undersampled samples taken in several LCT domains. In this paper, we present some novel sampling expansions involving signal reconstruction using samples of the linear canonical transform (LCT) of the signal in some specific LCT domains. © 2012 IOP Publishing Ltd.
Bhati-Kushwaha H.,Jaipur National University |
Malik C.P.,Jaipur National University
Turkish Journal of Biology | Year: 2013
Nanotechnology has opened new opportunities in the field of medical sciences and pharmaceuticals. Commercially, nanoparticles are in great demand in electronics, catalysis, chemistry, energy, and medicine. Today in nanoparticle production green synthesis, using biological material including medicinal plants as a starting material, is in vogue. In the present investigation the powder extract (stems and leaves) of an important medicinal plant, Verbesina encelioides, was used for the biosynthesis of bionanoparticles. The synthesized nanoparticles were screened and characterized by UV-visible spectrophotometer, scanning electron microscopy, X-ray diffraction, and FTIR analyses. The particles were then subjected to antimicrobial assay. Comparative analyses of the antimicrobial behavior of aqueous, ethanolic, and methanolic extracts and bionanoparticles against 2 bacteria (Escherichia coli and Vibrio cholerae) and 2 fungi (Aspergillus niger and A. flavus) are described. © TÜBİTAK.
Kaur R.,Jaipur National University |
Malik C.P.,Jaipur National University
International Journal of Pharmaceutical and Clinical Research | Year: 2014
Herbs are known as a natural source of medicines as well as other commercial products and have gained attention for many reasons such as low price, no side effects, solutions for chronic diseases and many preventive approaches, etc. Out of 2, 50,000 higher plant species, 80,000 species are medicinal important plants. Cissus quadrangularis L. is one of the important medicinal plants, belonging to family Vitaceae and common name is 'Hadjod'. It is a succulent plant found in warm tropical areas. The plant is well known in Ayurveda for its bone fracture healing properties. The literature survey revealed that the plant has some pharmacological properties such as free radical scavenging, anti microbial, anti bacterial, antioxidant, bone healing, anti ulcer, anti inflammatory, analgesic and diuretic properties. The plant extract is also useful in skin diseases, epilepsy, tumors, chronic ulcers, swellings, hemorrhage helminthiasis, anorexia, etc. The present review is an effort to focus on the medicinal importance of C. quadrangular is, its Botany, phytoconstituents and pharmacological reports.
Bhati-Kushwaha H.,Jaipur National University |
Malik C.P.,Jaipur National University
Indian Journal of Experimental Biology | Year: 2014
A simple and eco-friendly method for the synthesis of biogenic nanoparticles (NP's) using an aqueous solution of T. procumbens fresh plant extract (leaf and stem) as a bioreductant is reported. The prepared biogenic nanoparticles were well characterized using U.V. visible spectroscopy, scanning electron microscopy, X-ray diffraction and Fourier-transform infrared spectroscopy. The particles were confirmed to be elemental crystal by X-ray diffraction. The potential applications of biosynthesized nanoparticles as antimicrobial (antibacterial and antifungal) against pathogens Escherichia coli, Vibrio cholerae, Aspergillus niger and Aspergillus flavus were demonstrated.
Bairwa R.,Jaipur National University |
Sodha R.S.,Jaipur National University |
Rajawat B.S.,Jaipur National University
Pharmacognosy Reviews | Year: 2012
Trachyspermum ammi commonly known as 'Ajwain' is distributed throughout India and is mostly cultivated in Gujarat and Rajasthan. The fruit possesses stimulant, antispasmodic and carminative properties and is used traditionally as an important remedial agent for flatulence, atonic dyspepsia, diarrhea, abdominal tumors, abdominal pains, piles, and bronchial problems, lack of appetite, galactogogue, asthma and amenorrhoea. Medicinally, it has been proven to possess various pharmacological activities like antifungal, antioxidant, antimicrobial, antinociceptive, cytotoxic, hypolipidemic, antihypertensive, antispasmodic, broncho-dilating actions, antilithiasis, diuretic, abortifacient, antitussive, nematicidal, anthelmintic and antifilarial. Further, studies reveal the presence of various phytochemical constituents mainly carbohydrates, glycosides, saponins, phenolic compounds, volatile oil (thymol, -terpinene, para-cymene, and - and -pinene), protein, fat, fiber and mineral matter containing calcium, phosphorous, iron and nicotinic acid. These studies reveal that T. ammi is a source of medicinally active compounds and have various pharmacological effects; hence, it is encouraging to nd its new therapeutic uses.