Jackson, MS, United States

Jackson State University

Jackson, MS, United States

Jackson State University is a historically black university in Jackson, Mississippi, United States. Founded in 1877 in Natchez, Mississippi as Natchez Seminary by the American Baptist Home Mission Society of New York, the Society moved the school to Jackson in 1882, renaming it Jackson College, and developed its present campus in 1902. It became a state-supported public institution in 1940, and it is a member of the Thurgood Marshall College Fund. Wikipedia.

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Jackson State University and Warsaw University of Technology | Date: 2015-09-25

A composite coating and method for preparing the composite coating on titanium implants for tissue culture and tissue engineering is provided. The implants are characterized in that the titanium component to be coated is placed in a aqueous solution containing calcium cations, phosphate anions, and dispersed carbon nanoparticles (such as single layer graphene oxide or graphene oxide) in an amount of about 0.05%-1.50% by weight relative to the total weight of aqueous solution. The dimensions of the dispersed graphene oxide should be around, but not limited to, 300-800 nm (X-Y), while their thickness is about 0.7-1.2 nm. The aqueous solution with carbon nanoparticles is prepared by mixing for at least 72 h in temperature in range 20-35 C. and sonicated before electrodeposition process. In the prepared solution is further placed titanium which acts as cathode element (may be the implant), and anode which can be, for example, a platinum rod. Between the cathode and anode is set a potential from 1.3V to 1.7V which results in coating formation by electrodeposition. The titanium implant before the electrodeposition process is treated in sodium hydroxide of HF to improve coating formation and thickness.

Dasari S.,Jackson State University | Bernard Tchounwou P.,Jackson State University
European Journal of Pharmacology | Year: 2014

Cisplatin, cisplatinum, or cis-diamminedichloroplatinum (II), is a well-known chemotherapeutic drug. It has been used for treatment of numerous human cancers including bladder, head and neck, lung, ovarian, and testicular cancers. It is effective against various types of cancers, including carcinomas, germ cell tumors, lymphomas, and sarcomas. Its mode of action has been linked to its ability to crosslink with the purine bases on the DNA; interfering with DNA repair mechanisms, causing DNA damage, and subsequently inducing apoptosis in cancer cells. However, because of drug resistance and numerous undesirable side effects such as severe kidney problems, allergic reactions, decrease immunity to infections, gastrointestinal disorders, hemorrhage, and hearing loss especially in younger patients, other platinum-containing anti-cancer drugs such as carboplatin, oxaliplatin and others, have also been used. Furthermore, combination therapies of cisplatin with other drugs have been highly considered to overcome drug-resistance and reduce toxicity. This comprehensive review highlights the physicochemical properties of cisplatin and related platinum-based drugs, and discusses its uses (either alone or in combination with other drugs) for the treatment of various human cancers. A special attention is paid to its molecular mechanisms of action, and its undesirable side effects. © 2014 Elsevier B.V.

A study that was conducted to examine size and shape dependent second order nonlinear optical properties of nanomaterials and their application in biological and chemical sensing is presented. Benzil was the first material that proved relatively easy to grow into large single crystals. Over the last two decades the study of nonlinear optical processes in organic and polymer systems has enjoyed rapid and sustained growth. Nonlinear optics deals with the interaction of applied electromagnetic fields in various materials, which generates new electromagnetic fields altered in frequency, phase, or other physical properties. A nanoparticle has a rather large number of atoms, but its size is comparable, with characteristic dimensions describing the behavior of electrons and holes, thus creating an intermediate regime between molecules and bulk crystals.

Agency: NSF | Branch: Standard Grant | Program: | Phase: HIST BLACK COLLEGES AND UNIV | Award Amount: 350.00K | Year: 2016

Jackson State University is examining the effect of active flipped learning on student success in STEM. The project team will structure an intervention around mathematics, physics, and engineering courses and conduct research to produce knowledge that can be used to enhance African American students learning and engagement in STEM. The goal is to implement and assess the effectiveness of an evidence-based active flipped learning model on student outcomes.

The project will be implemented using five experimental periods that will apply flipped learning and mixed traditional classroom lecture with active flipped learning. The activities will be guided by relevant affective, cognitive, and behavioral models. Participants will be provided data-driven personalized feedback, scaffolds, and learning tasks through advanced smart technologies. A series of surveys and interviews will be conducted to compare students learning engagement, empowerment, self-efficacy, and satisfaction with active flipped learning. The project could catalyze a paradigm shift replacing passive learning with active learning in STEM education at HBCUs and other institutions.

This project is supported by the Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) Targeted Infusion and Broadening Participation Research in Education tracks. This program supports ideas to create and study new models and innovations in STEM teaching and learning, investigate the underlying issues affecting the differential participation and success rates of students from underrepresented groups, and produce knowledge to inform STEM education practices and interventions.

Agency: NSF | Branch: Standard Grant | Program: | Phase: CENTERS FOR RSCH EXCELL IN S&T | Award Amount: 1000.00K | Year: 2016

The Historically Black Colleges and Universities Research Infrastructure for Science and Engineering (HBCU-RISE) activity within the Centers of Research Excellence in Science and Technology (CREST) program supports the development of research capability at HBCUs that offer doctoral degrees in science and engineering disciplines. HBCU-RISE projects have a direct connection to the long-term plans of the host department(s) and the institutional mission, and plans for expanding institutional research capacity as well as increasing the production of doctoral students in science and engineering. With support from the National Science Foundation, Jackson State University (JSU) aims to develop a research and educational program that will prepare chemistry undergraduate (RISE Scholars) and graduate students (RISE Fellows) to be globally competitive by: recruiting highly talented doctoral students with an interest in nanochemistry; providing faculty-led mentoring of interdisciplinary research activities for doctoral students; supporting leadership development activities for doctoral students; developing new courses toward a unique updated curriculum for the JSU chemistry doctoral program; upgrading the lab equipment to support the expansion of nanochemistry research; and generating collaborative-interdisciplinary research among faculty members and doctoral students who will give presentations and publish. The purposes of this proposal are to (a) improve and expand the institutions research and educational capability in order to prepare African Americans and women to become effective future generation of scientists for our nation and (b) to increase the number and quality of minority students through the effective preparation of the next generation of US scientists.

The JSU-RISE interdisciplinary faculty mentors will collaborate on a research project pertaining to the chemical design and development of novel multifunctional carbon quantum dots (CQDs) based fluorescence imaging materials and demonstrate their possible application for biological and chemical imaging. The goal is to establish synthetic procedures to develop different types CQDs as imaging materials for targeted sensing of several pathogenic bacteria and viruses simultaneously. The proposed research applies an integrated approach combining nanoscience, organic chemistry, and theory to construct interfaces that give quantitative information about chemical activities at the nano interface. The research activities will include: a) developing synthetic procedures for bright and photo stable CQDs such as graphene oxide quantum dots, carbon dots and metal doped graphene dots; b) measuring the two photon absorption cross section by measuring two-photon luminescence intensity; c) finding the photo-stability and biocompatibility of the developed CQDs; d) demonstrating CQDs based near IR imaging of bio-molecules for the selective and simultaneous sensing of several waterborne pathogens; and e) using quantum chemical calculations to understand the interaction between CQDs and biological molecules. The goals of this proposal are well-aligned with the ongoing developmental plan of JSU to become one of the regions foremost centers for nanotechnology with the aim of making devices that can be used for daily life applications.

Agency: NSF | Branch: Cooperative Agreement | Program: | Phase: RESEARCH INFRASTRUCTURE IMPROV | Award Amount: 6.00M | Year: 2016

Non-technical description
Methods to convert biomass into energy involve burning in the presence of oxygen (combustion), reaction at high temperature with controlled amount of oxygen and /or steam (gasification), and decomposition at elevated temperature in the absence of oxygen (pyrolysis). This project focuses on biomass pyrolysis to produce fuels and biochar and then chemically modify biochar for use in applications related to carbon dioxide capture, water purification, and food production. The project is interdisciplinary and is a collaboration among four institutions (Jackson State University, University of Mississippi, University of Delaware, and the University of Wyoming) in three states. The project aims to diversify the workforce through partnerships with Minority Serving Institutions (MSIs) in the region, hiring and mentoring of early career faculty and postdoctoral fellows, and training of graduate and undergraduate students.

Technical description
Using solar energy with chemical catalysis and steam pyrolysis, this project aims to produce liquid fuels and value-added biochar from biomass (e.g. corn stover). The goal is to develop technologies for biomass refineries that produce net zero or negative CO2 emission. The project combines experimental work with computations based on Density Functional Theory (DFT) to better understand the thermodynamics, kinetics, and transport in the chemical looping energy production system. The photochemical and ultrasonic chemistry and functionalization of biochar will use graphene related nanostructures and enable technologies for CO2 capture and utilization, water purification, and soil quality improvement.

The project is interdisciplinary and addresses science and engineering issues in biomass conversion and will contribute to advances in materials chemistry, heterogeneous catalysis, and reaction theories. Each of the collaborating institutions brings complementary expertise in research and will hire new faculty in the areas related to Food, Energy, and Water. The project seeks to diversify the workforce through partnerships with Minority Serving Institutions in the region, national laboratories, and other national and international institutions.

Agency: NSF | Branch: Continuing grant | Program: | Phase: CENTERS FOR RSCH EXCELL IN S&T | Award Amount: 1.00M | Year: 2016

Interdisciplinary Nanotoxicity Center

With National Science Foundation support, Jackson State University will continue development of the Interdisciplinary Nanotoxicity Center. The Center goal is to enhance knowledge of basic properties and environmental characteristics, toxicity, and applications of nanomaterials. There is a compelling need for studying potential toxicity of nanomaterials and advancing efficient, fast and inexpensive computational approaches to predict toxicity of new species. Understanding of structures, characteristics and biological activities of man-made nanomaterials is critical to prediction of their impacts on the environment and human health. Nanoparticle exposure is common, but short- and long-term exposure effects are currently not fully understood, especially since the primary and agglomerate sizes, surface area, and the characteristics of the surface play such important roles. Conversely, nanotechnology can also be used to create new nanomedicines, sensors, pollutant filters and catalysts with important societal benefits.

The Interdisciplinary Nanotoxicity Center focuses on two research subprojects: addressing nanomaterials discovery and deployment. Subproject 1 focuses on multifunctional nanoparticles and their model counterparts: structures, properties, interaction with environment and applications. The aim of this project is to systematically study structure, energetics and optics of metal and semiconductor nanoparticles and their bioconjugates in various environments. Multifunctional environmental safe magnetic core-plasmonic shell nanopaticle based assay for the detection of toxic pathogens selectively from water will be designed and developed, and the possible use of multifunctional nanoparticles for selective removal of toxic pathogens from drinking water is investigated.

Subproject 2 investigates toxicity of nanoparticles as a function of environmental factors: experimental studies and computational modeling to include different aspects of the development and production of nanomaterials and investigation of their toxicity. The overarching goal is to develop an operational model for directing production of green metal oxide nanoparticles and to conduct in vitro and in vivo toxicological studies under selected environmental conditions by using engineered metal oxide nanoparticles of controlled size and shape. In addition, computational studies are carried out to develop reliable computational models effective for prediction of physico-chemical characteristics and toxicity of nanomaterials.

Both research areas are strongly interconnected and designed to enhance knowledge of basic properties and environmental characteristics, toxicity, and applications of nanomaterials. The Center utilizes the Universal Design for Learning model to maximize learning outputs of diverse student populations.

Agency: NSF | Branch: Standard Grant | Program: | Phase: ALLIANCES-MINORITY PARTICIPAT. | Award Amount: 1.07M | Year: 2016

The United States has traditionally been a global leader in Science, Technology, Engineering, and Mathematics (STEM), and as a means to address the national need for the U.S. to remain globally competitive in the STEM disciplines, the inclusion of an untapped pool of creative, talented, and intelligent students historically underrepresented in STEM who earn a Ph.D. is warranted. Jackson State University (JSU), a Historically Black University, has a strong track record for preparing primarily African-American graduate students in biology, chemistry, mathematics, environmental science, computer science, and engineering for STEM doctoral degrees. To date, JSUs Bridge to the Doctorate (BD) program has produced 34 Ph.D. graduates from underrepresented groups and 139 BD Fellows have been admitted into doctoral programs. Through their BD program, JSU will provide well-qualified and diverse faculty members for U.S. universities and colleges, as well as impact the number of scientists, mathematicians, and engineers holding the doctorate and entering the workforce.

Jackson State University will execute a BD program that is based upon rich and challenging research and academic experiences, the development and implementation of an independent development plan (IDP), professional long term goals and objectives, the utilization of STEM summer extramural research internship experiences at potential graduate school sites for the BD Fellows targeted Ph.D. program, and an international research experience. The BD program has four objectives that are focused on 1) research and academic preparation, 2) enrichment activities, 3) national and international partnerships, and, 4) evaluation and student tracking. These activities along with sufficient financial support from the Louis Stokes Mississippi Alliance for Minority Participation (LSMAMP) program, rigorous curricula, and committed mentoring will enable their BD program to continue to reach their goal which is to prepare and increase the quality and quantity of students historically underrepresented in STEM entering the Ph.D. pipeline.

Agency: NSF | Branch: Continuing grant | Program: | Phase: DISCOVERY RESEARCH K-12 | Award Amount: 1.75M | Year: 2016

The Discovery Research K-12 program (DRK-12) seeks to significantly enhance the learning and teaching of science, technology, engineering and mathematics (STEM) by preK-12 students and teachers, through research and development of innovative resources, models and tools (RMTs). Projects in the DRK-12 program build on fundamental research in STEM education and prior research and development efforts that provide theoretical and empirical justification for proposed projects.

This project at Jackson State University will investigate the effectiveness of a teacher academy resident model to recruit, license, induct, employ, and retain middle school and secondary science and mathematics teachers for high-need schools in the South It will prepare new, highly-qualified science and mathematics teachers from historically Black universities in high-needs urban and rural schools. The project involves a partnership among three historically Black universities (Jackson, State University, Xavier University of Louisiana, and the University of Arkansas at Pine Buff), and diverse urban and rural school districts in Jackson, Mississippi; New Orleans, Louisiana; and Pine Bluff Arkansas region that serve more than 175,000 students.

Participants will include 150 middle and secondary school teacher residents who will gain clinical mentored experience and develop familiarity with local schools. The 150 teacher residents supported by the program to National Board certification will obtain: state licensure/certification in science teaching, a master?s degree, and initiation. The goal is to increase teacher retention and diversity rates. The research question guiding this focus is: Will training STEM graduates have a significant effect on the quality of K12 instruction, teacher efficacy and satisfaction, STEM teacher retention, and students? science and mathematics achievement? A quasi-experimental design will be used.to evaluate projects effectiveness.

Shahbazyan T.V.,Jackson State University
Nano Letters | Year: 2013

Metal photoluminescence (MPL) originates from radiative recombination of photoexcited core holes and conduction band electrons. In metal nanostructures, MPL is enhanced due to the surface plasmon local field effect. We identify another essential process in plasmon-assisted MPL - excitation of Auger plasmons by core holes - that hinders MPL from small nanostructures. We develop a microscopic theory of plasmon-enhanced MPL that incorporates both plasmon-assisted enhancement and suppression mechanisms and derive the enhancement factor for MPL quantum efficiency. Our numerical calculations of MPL from Au nanoparticles are in excellent agreement with the experiment. © 2012 American Chemical Society.

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