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Apaydin M.,Izmir Ataturk Education and Research Hospital | Varer M.,Izmir Ataturk Education and Research Hospital | Oztekin O.,Izmir Education and Research Hospital
Radiology and Oncology

Background. Von Hippel Lindau disease is an autosomal dominant multisystem/multitumoral cancer disease diagnosed by clinical, radiologic and genetic findings. Its prevalence has been estimated to be of 1/36000 inhabitants. The tumours can be benign or malignant.Case report. We represent MR findings of a family with ten children. Mother and five siblings had von Hippel-Lindau disease.Conclusions. Radiologic imaging is very important for the early diagnosis and treatment of asymptomatic patients. Diagnosing it early is important because the tumours in von Hippel Lindau disease are treatable. Also, an early detection allows the patient's survival and quality of life. A multidisciplinary team approach is important in screening. Source

Kececi Y.,Izmir Education and Research Hospital | Dagistan S.,Izmir Education and Research Hospital
International Surgery

Macromastia causes several health problems, and reduction surgery alleviates them successfully. The purpose of this study was to investigate whether reduction mammaplasty improves possible impairments on pulmonary functions related to macromastia. Thirtyone patients participated in the study. Pulmonary function tests were performed before and 3 months after surgery with a spirometry. Preoperative and postoperative pulmonary function values were compared using a paired t test. Two patients were found to have mild restriction in preoperative spirometric analysis, and they went to normal range in postoperative analysis. All other patients were assessed as having normal values in both preoperative and postoperative analyses. Preoperative and postoperative forced vital capacity values were 2.72 ± 0.06 and 2.79 ± 0.05 L, respectively. The difference was statistically significant (paired t test, P = 0.014). The other parameter in which breast reduction had statistically significant improvement was forced vital capacity performed/ predicted ratio (paired t test, P = 0.041). Additionally, the weight of resected breast tissue correlated significantly with the change of forced vital capacity (Pearson correlation coefficient = 0.379, P = 0.036). Breast reduction surgery improves the pulmonary function parameters that are mainly influenced by restrictive states. This result led us to consider that macromastia causes a relative restriction in chest wall compliance, and reduction of breast weight may enhance chest wall compliance and improve pulmonary function. Source

Kececi Y.,Izmir Education and Research Hospital | Sir E.,Izmir Education and Research Hospital
Journal of Foot and Ankle Surgery

Repairing distal lower limb soft tissue defects remains challenging for reconstructive surgeons. Relatively few procedures have real efficiency and low morbidity. Since its initial description, the distally based sural flap has been used increasingly for this indication. However, controversy exists about the upper limit of the skin paddle of the sural flap. In the present series, 11 patients underwent surgery with distally based sural flaps. In 6 patients, the flap skin paddle was partially or totally placed beyond this controversial limit on the proximal calf region. To increase the skin irrigation of this region, whole mesenteric tissue under the deep fascia of the leg was included in the flap. Venous congestion and distal tip necrosis can impair the success of flap surgery. To overcome these problems, the flap pedicle was not passed through the subcutaneous tunnel. All flaps survived completely, and no cases of venous congestion developed. Thus, extending the donor area to the upper part of the leg is a reliable maneuver to repair more distal defects of the leg and foot, and abstaining from passing the pedicle through a subcutaneous tunnel could contribute to a decreased risk of venous congestion. © 2012 American College of Foot and Ankle Surgeons. Source

Oztekin O.,Izmir Education and Research Hospital | Calli C.,Ege University | Adibelli Z.,Izmir Education and Research Hospital | Kitis O.,Ege University | And 2 more authors.
Radiologia Medica

Purpose: In this retrospective study, we evaluated the contribution and role of diffusion-weighted imaging (DWI) in differentiating acute and chronic forms of brucellar spondylodiscitis. We also describe the characteristics and some indistinguishable features of brucellar spondylodiscitis on magnetic resonance imaging (MRI) to emphasise the importance and limitations of MRI. Materials and methods: MRI examinations of 25 patients with brucellar spondylodiscitis were retrospectively reviewed and analysed by two experienced radiologists. Signal and morphological changes were assessed. The imaging characteristics of acute and chronic forms of spondylodiscitis were compared. Both discriminative imaging findings of brucellar spondylodiscitis and some uncommon findings were interpreted. Results: Of 25 patients with spinal brucellosis, eight had thoracic, ten had lumbar, five had both thoracic and lumbar and two had both lumbar and sacral vertebral involvement. We detected posterior longitudinal ligament elevation in 11 patients, epidural abscess formation in 11 and paravertebral abscess formation in nine. Ten patients had cord compression and eight had root compression. Three patients had facet-joint involvement, and one had erector spinae muscle involvement. Eight patients (32%) were in the acute stage, six (24%) in the subacute stage and 11 (44%) in the chronic stage. Vertebral bodies, vertebral end plates and intervertebral disc spaces were hypointense and hyperintense in the acute stage, whereas they were hypointense and heterogeneous in the subacute and chronic stages on T1- and T2-weighted images, respectively. In the acute stage on the DWI series, vertebral bodies, end plates and discs were all hyperintense but hypointense in the chronic stage. Conclusions: Although conventional MRI has several advantages over other imaging modalities and is very useful in the differential diagnosis between brucellar spondylodiscitis and other spinal pathologies, it has some difficulties in discriminating acute and chronic forms of spondylodiscitis. DWI is a sensitive, fast sequence that has the potential for differentiating acute and chronic forms of spondylodiscitis, which makes it crucial in spinal imaging. © 2010 Springer-Verlag Italia. Source

Curuk M.A.,Cukurova University | Cavusoglu A.C.,Izmir Education and Research Hospital | Arican H.,Izmir Education and Research Hospital | Uzuncan N.,Izmir Education and Research Hospital | Karaca B.,Izmir Education and Research Hospital

We describe Hb Sarrebourg [β131(H9)Gln→Arg, CAG>CGG] in four heterozygous members of a Turkish family. It was associated with iron deficiency in the proband. © 2010 Informa Healthcare USA, Inc. Source

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