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Vardar E.,Bozyaka Izmir Training and Research Hospital | Gunay Yardim B.,Manisa State Hospital | Vardar R.,Ege University | Olmez M.,Izmir Tepecik Training and Research Hospital
Turk Patoloji Dergisi | Year: 2015

Invasive micropapillary carcinoma is a recently identified neoplasm. A 77-year-old-female was admitted to the hospital due to progressive loss of weight and nausea. Endoscopic biopsy of the antral/prepyloric located mass was diagnosed as moderately differentiated adenocarcinoma. Subtotal gastrectomy and regional lymph node resection were performed. The tumor was composed of moderately differentiated cells arranged in micropapillary structures with only a few poorly formed glandular foci in lamina propria. Immunohistochemically, neoplastic cells of micropapillary and focal conventional adenocarcinoma areas were diffusely positive for pancytokeratin, cytokeratin 7 and epithelial membrane antigen. In micropapillary areas, membranous and peripheral cytoplasmic positivity with epithelial membrane antigen in outside of the cell clusters called “inside-out polarity” pattern that is characteristic for invasive micropapillary carcinoma were seen. Invasive micropapillary carcinoma is very rare in the stomach in the English literature. © 2015, Federation of Turkish Pathology Societies. All rights reserved. Source

Ce P.,Bozyaka Izmir Training and Research Hospital | Koskderelioglu A.,Bozyaka Izmir Training and Research Hospital | Coban G.,Bozyaka Izmir Training and Research Hospital | Gedizlioglu M.,Bozyaka Izmir Training and Research Hospital | And 2 more authors.
Experimental and Clinical Transplantation | Year: 2012

Objectives: Neurologic problems have a major effect on the survival and quality of life in renal transplant recipients. This study sought to review the incidence and character of neurologic complications after renal transplant. Materials and Methods: Medical records of 319 renal transplant recipients admitted to the Transplant Outpatient Clinic were reviewed retrospectively for neurologic complications. Results: Of the 319 transplant recipient patients reviewed, 124 patients (39%) were women and 193 patients (61%) were men. The mean patient age was 41 ± 11 years, and the transplanted kidney was received from deceased donors in 161 patients (51%) and living donors in 158 patients (49%). There were 50 patients (16%) who had neurologic complications, most commonly herpes zoster infection associated with immunosuppressive medication. Only 1 patient, who had glioblastoma multiforme, died. Treatment included corticosteroids in 296 patients (93%) and calcineurin inhibitors (including tacrolimus) in 111 patients (35%). Conclusions: Neurologic complications are common after renal transplant. Most complications are associated with immunosuppressive medications. © Başkent University 2012 Printed in Turkey. All Rights Reserved. Source

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