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Oztekin D.,center | Ozcinar E.,center | Kose C.,center | Gulhan I.,Izmir Bozyaka Education and Research Hospital | And 2 more authors.
Medical Principles and Practice | Year: 2013

Objective: To investigate the role of ultrasound guidance in intrauterine insemination (IUI). Materials and Methods: A retrospective study was conducted. The data was collected from the records of 197 couples with unexplained infertility who underwent IUI with a total of 267 IUI cycles in the in vitro fertilization center of our hospital between January 2009 and December 2010. Results: Of the 267 IUI cycles, 145 were carried out as US-guided, while 122 cycles IUI were performed with a blind procedure. In the US-guided IUI and blinded IUI groups, the pregnancy rates were 23.4 and 13.9%, respectively. The difference between the groups was statistically significant (p = 0.049), thereby indicating that US guidance improves pregnancy rates. In the US-guided IUI group, 9.7% of the cases were difficult, while in the blinded IUI group, 26.2% were difficult and the difference between the groups was also statistically significant (p < 0.001). Conclusion: US guidance in IUI improves pregnancy rates and reduces the frequency of difficult IUI. Copyright © 2012 S. Karger AG, Basel. Source

Namdaroglu S.,Izmir Bozyaka Education and Research Hospital | Tekgunduz E.,Ankara Oncology Research Hospital | Altuntas F.,Ankara Oncology Research Hospital
Hematology Reports | Year: 2016

Essential thrombocythemia (ET) is a Philadelphia chromosome (Ph)-negative myeloproliferative neoplasm. It is characterized by thrombocytosis and megakaryocytic hyperplasia of the bone marrow with JAK2V617F mutation. Iron-refractory iron deficiency anemia (IRIDA) is an autosomal recessive disorder, which is mainly characterized by iron deficiency anemia not responding to oral iron intake, but partially responding to parenteral iron therapy. Recently, it has been shown that IRIDA has stemmed from mutations in the gene TMPRSS6, which encodes a transmembrane serine protease (matriptase- 2) expressed by the liver. Renal cell carcinoma (RCC) accounts for 2-3% of all cancers. As the most common solid lesion in the kidneys, it represents approximately 90% of all renal malignancies. Approximately 30% of patients with symptomatic RCCs seem to display paraneoplastic syndromes. The symptom that may result from erythrocytosis is the most wellknown paraneoplastic hematological event. Here, we report a patient who presents with coexistence of RCC and thrombocytosis, which hasn’t been caused by hormonal factors that are produced in tumor cells. This patient has been therefore diagnosed with ET. The patient who was expected to display RCC with polycythemia, conversely present with IRIDA. © S. Namdaroğlu et al. 2016. Source

Uyar I.,Ege Maternity and Gynecology Training and Research Hospital | Gulhan I.,Izmir Bozyaka Education and Research Hospital | Sipahi M.,Ege Maternity and Gynecology Training and Research Hospital | Hanhan H.M.,Ege Maternity and Gynecology Training and Research Hospital | Ozeren M.,Ege Maternity and Gynecology Training and Research Hospital
Fertility and Sterility | Year: 2011

Objective: To present a case of unicornuate uterus with ipsilateral ectopic ovary and renal agenesis. Design: Case report. Setting: Research hospital. Patient(s): A 26-year-old woman with a 5-year history of primary infertility was admitted to our clinic. A unicornuate uterus without contralateral horn, with ipsilateral ectopic ovary and renal agenesis, was diagnosed. Intervention(s): Diagnostic laparoscopy, ovarian stimulation. Main Outcome Measure(s): During laparoscopy, a unicornuate uterus without a contralateral horn, together with ectopic ovary, was observed. Result(s): We visualized the right ectopic ovary on ultrasound after ovarian stimulation. Conclusion(s): We present a rare clinical entity that exhibits a unicornuate uterus without a contralateral horn, with ipsilateral right ectopic ovary and renal agenesis together. We conclude that ovarian stimulation is a useful approach in the diagnosis of ectopic ovaries. Copyright © 2011 American Society for Reproductive Medicine, Published by Elsevier Inc. Source

Yalbuzdag S.A.,Izmir Bozyaka Education and Research Hospital | Sarifakioglu B.,Namik Kemal University | Afsar S.I.,Baskent University | Celik C.,Sevket Yilmaz Education and Research Hospital | And 4 more authors.
Journal of Stroke and Cerebrovascular Diseases | Year: 2015

Background In recent years, vitamin D deficiency has been suggested as a risk factor for ischemic stroke and stroke severity in both animal models and clinical studies. In this retrospective study, we investigated the relationship between 25-hydroxyvitamin D [25(OH)D] levels and functional outcomes in stroke patients during neurological rehabilitation program. We also investigated whether there is an association between 25(OH)D levels and cognitive impairment. Methods The study included the medical records of 120 stroke patients who participated in a neurological rehabilitation program. The motor and cognitive components of the Functional Independence Measurements of all patients at admission and discharge were recorded. The Functional Ambulatory Scale was used to assess motor functional status, and the Turkish-validated version of the minimental state examination test was used to assess cognitive status. Results A significant correlation was found between 25(OH)D level and cognitive impairment among patients who had ischemic strokes. High levels of 25(OH)D were associated with greater functional gain during the rehabilitation program in both ischemic stroke patients and hemorrhagic stroke patients. Conclusions High 25(OH)D levels might be associated with greater functional improvement and with less cognitive impairment in stroke patients. © 2015 by National Stroke Association. Source

Kose S.,Izmir Tepecik Education and Research Hospital | Tatar B.,Izmir Tepecik Education and Research Hospital | Atalay S.,Izmir Tepecik Education and Research Hospital | Erden M.,Izmir Tepecik Education and Research Hospital | Tatar E.,Izmir Bozyaka Education and Research Hospital
Renal Failure | Year: 2013

Background: Incidence of allergic reactions is increased in hemodialysis (HD) patients. However, the prevalence of latex allergy is not exactly known in HD patients. The aim of this present study is to determine the prevalence of latex allergy in HD patients. Methods: A total of 205 adult HD patients were included in the study. Questionnaires were completed during patient interviews, and their consents were provided. Latex prick test and latex specific IgE test (HY-TEC, K82) were performed. Mean age of the patients was 52 ± 14 (25-79) years, and 61% was male. Mean dialysis duration was 38 months, and 21% of them were diabetics. Only five patients had allergic complaints in their histories, and none of them had severe anaphylaxis history. Latex prick test was positive in two patients. Latex specific IgE test was positive in five patients. Overall latex sensitivity was defined as 3.4%. Conclusion: No increased prevalence in latex allergy was determined in HD patients. Latex allergy incidence may be increased in atopic HD patients. Therefore, the use of latex products should be avoided as much as possible especially in atopic HD patients. © 2013 Informa Healthcare USA, Inc. Source

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