Bhateja P.K.,Bhojia Dental College and Hospitals |
Singh R.,iversity Mullana
International Journal of Toxicological and Pharmacological Research | Year: 2016
The present study was undertaken to evaluate the antioxidant effect of aqueous extract of Acacia tortilis polysaccharide (AEATP) from gum exudates in (STZ)-NAD induced diabetic rats. Male albino wistar rats were divided into control, diabetic, diabetic rat+ glimepiride, diabetic rat+250, 500, 1000 mg/kg of AEATP. Fasting blood glucose (FBG), serum insulin, tissue superoxide dismutase (SOD), catalase (CAT), GPx, GSH, and malondialdehyde (MDA) were measured in liver, kidney and pancreas. In vitro antioxidant levels were measured through DPPH, ABTS, and FRAP methods. Positive antioxidant activities of AEATP were confirmed by DPPH, ABTS and FRAP assays. Administration of STZ significantly increased fasting blood glucose level and oxidative stress by decreasing SOD, Catalase, GPx activities and GSH level whereas increasing MDA levels. AEATP showed significant reduction (p<0.05) in fasting blood glucose level compared to diabetic rats. Tissue SOD, Catalase, GPx activities and GSH level along with MDA levels were attenuated in diabetic rats by treatment with AEATP. These data suggested that AEATP possess antioxidant and hypoglycemic effects by reducing oxidative stress in diabetic rats. © 2016, International Journal of Toxicological and Pharmacological Research. All rights reserved.
Kamboj S.,iversity Mullana |
Sharma D.,iversity Mullana |
Nair A.B.,iversity Mullana |
Bala S.,iversity Mullana |
And 5 more authors.
Der Pharmacia Lettre | Year: 2011
A simple, sensitive, economical and reproducible UV-Spectrophotometric method was developed for the estimation of DTPA in topical gel formulations. The method is based on NaFeDTPA complex formation by the reaction of DTPA with ferric chloride in 0.1N HCl. Optimum conditions for the reaction were investigated and absorbance was read at λmax at 272 nm. Bears law was obeyed in the range of 5μg/mL-50μg/mL with correlation of 0.9998. The detection and quantitation limits were found to be 0.8701 and 2.6366 μg/mL respectively. The proposed method was successfully applied for the determination of DTPA in topical gel formulations. Accuracy was examined through recovery studies. The results show that the procedure is accurate, precise and reproducible (relative standard deviation < 1 %), while being simple, cost effective and less time consuming, which proves the suitability of the proposed method for the estimation of DTPA in topical gel formulations.
Gupta V.,iversity Mullana |
Saini R.K.,Bundelkhand University |
Verma M.,iversity Mullana
Advances in Intelligent Systems and Computing | Year: 2016
In our paper, we prove common fixed-point theorem on the basis of control functions in FM-spaces. Using the fuzzy edition of the Banach contraction principle, the present theorem generalized the Banach contraction principle using the continuous control function. Condition of continuity for mappings P;Q; S and T is not required. Our result generalizes the accumulation of compact subsets of Y; where the assemblage HM itself is an FM-space. Here, we prove the result for two pairs of single-valued and set-valued owc mappings. Also, we give example to justify our result. © Springer Science+Business Media Singapore 2016.
Arora A.K.,iversity Mullana |
Jaswal V.S.,iversity Mullana |
Singh K.,iversity Mullana |
Singh R.,iversity Mullana
Oriental Journal of Chemistry | Year: 2016
Metal oxides/ Mixed metal oxides have wide applications as catalyst, Adsorbents, Superconductors, semiconductors, ceramics, antifungal agents and also have spacious applications in medicines. This review article is focused on their applications as photocatalyst in various organic reactions. © 2016, Oriental Scientific Publishing Company. All rights reserved.
Katiyar M.,iversity Mullana |
Sinha H.P.,iversity Mullana |
Gupta D.,iversity Mullana
International Journal of Applied Engineering Research | Year: 2014
Advancement in wireless sensor networks technology enables a wide range of applications such as health care, industrial automation, ambient conditions monitoring and security and defense systems. WSNs designers are facing many challenges in meeting application requirements e.g. reliability, fault tolerance, lifetime, throughput and responsiveness etc as application requirements and environmental conditions change over time. Failure of WSN may result catastrophic consequences like loss of life in the case of health care application and major disasters in the case of defense systems. This paper presents a probabilistic model for reliability analysis in WSNs by adding redundancy within a sensor node. © Research India Publications.
Garg A.K.,iversity Mullana
Journal of Microwaves, Optoelectronics and Electromagnetic Applications | Year: 2011
Several optical network switching paradigms have been under intensive research to support rapidly increasing bandwidth requirements. Of all these paradigms, optical burst switching (OBS) is a promising switching paradigm for the next-generation Internet infrastructure. Despite the significant contributions of OBS to high speed networks such as dynamic connection setup and strong separation between data and control plane, there are several issues that are to be resolved because the present OBS research studies have many differences and thus need further study. In this paper, some of author's own past researches have been summarized to overcome few issues of OBS; related to network architectures, contention, burst assembly, congestion, complex scheduling schemes, quality of service (QoS), burst dropping, routing etc. © 2011 SBMO/SBMag.
Kumar S.,iversity Mullana |
Hitendra,iversity Mullana |
Bhatia M.,iversity Mullana |
Garg L.N.,iversity Mullana |
Gupta S.,iversity Mullana
Inflammopharmacology | Year: 2013
Aim: To assess the protective efficacy of Strobilanthes callosus against the acute and chronic inflammation on rat model. Methods: Inflammation was induced by carrageen and Freund's complete adjuvant in plantar surface of the rats. The ethanol, chloroform and petroleum ether extracts in three divided doses (100, 200 and 400 mg/kg) were administered orally. Diclofenac sodium (10 mg/kg), prednisolone (5 mg/kg) and methotrexate (0.5 mg/kg) were used as standard. The statistical significance between means was analyzed using a one-way analysis of variance followed by Tukey's multiple comparison test. A p <0.005 was considered as statistically significant. Results: Pet. ether (200 and 400 mg/kg) and ethanol extract (100 and 400 mg/kg) showed statistically significant (p < 0.001) effect in analgesic activity. In a carrageen-induced model, only pet. ether extract (100 and 400 mg/kg) confirmed statistically significant effect (p < 0.001) at every interval (four in all) of 1 h. In Freund's adjuvant model, Pet ether and ethanol extract (200 and 400 mg/kg) have shown statistically significant effect (p < 0.001) and in case of chloroform extract only single dose (400 mg/kg) were observed statistically significant results considered to be anti-arthritic effects. The histopathology pictures showed there was positive inhibition of arthritis at a certain level in different groups compared to positive control group. Conclusion: Pet. ether and ethanol extracts of S. callosus were observed to have a promising efficacy against acute and chronic inflammation. © 2012 Springer Basel AG.
Pal A.,Kurukshetra University |
Kumar H.,National Institute of Technology Jalandhar |
Maan R.,iversity Mullana |
Sharma H.K.,iversity Mullana
Journal of Solution Chemistry | Year: 2013
Densities and ultrasonic speeds have been measured over the whole composition range for binary liquid mixtures of dipropylene glycol dimethyl ether, CH3(OC3H6)2OCH3, with methyl acetate, ethyl acetate, and n-butyl acetate using an Anton Paar DSA 5000 M density and speed sound analyzer at T = (288.15, 293.15, 298.15, 303.15, and 308.15) K and atmospheric pressure in order to evaluate the behavior of these binaries. From these data excess the molar volume, V m E, and deviation in isentropic compressibility, â̂†κ S, have been calculated. These excess properties have been fitted with the Redlich-Kister type polynomial equation to get their coefficients and standard deviations which provide a base for discussing the forces operating in solutions. © 2013 Springer Science+Business Media New York.