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Razo-Zapata I.S.,Monterrey Institute of Technology | Mex-Perera C.,Monterrey Institute of Technology | Monroy R.,ITESM
Journal of Systems and Software

This paper presents a set of methods for building masquerade attacks. Each method takes into account the profile of the user to be impersonated, thus capturing an intruder strategy. Knowledge about user behavior is extracted from several statistics, including the frequency at which a user types a specific group of commands. It is then expressed by rules, which are applied to synthesize computer sessions that mimic the attack as ordinary user behavior. The masquerade attack datasets have been validated by making a set of Intrusion Detection Systems (IDS) try to detect user impersonation, this way showing the capabilities of each masquerade synthesis method for evading detection. Results demonstrate that a better performance of masquerade attacks can be obtained by using methods based on behavioral rules rather than those based only on a single statistic. Summing up, masquerade attacks exhibit a good strategy for bypassing an IDS. © 2012 Elsevier Inc. All rights reserved. Source

Alexandrov N.,Barcelona Supercomputing Center | Alexandrov N.,University of Reading | Alexandrov V.,Barcelona Supercomputing Center | Ramirez R.,ITESM
Procedia Computer Science

This paper is focused on the role of Computational Science and emerging technologies in the natural sciences education at university level. We outline our Integrated Metacognitive Process Model (IMPM) and our Collaborative Learning approach based on Collaborative Creative Cross-Pollination activity model at postgraduate level. We present our multidisciplinary approach based on the following three components: the existence of multidisciplinary research environment (non-silos departmental culture), computational science research methods as core part of the curricula and collaborative teaching activities facilitated by novel collaborative tools using Collaborative Creative Cross-Pollination. Some results showing the advantages of such an environment and approach are presented. The initial results have shown overall average improvement of the average marks with around 5% plus clear satisfaction of the students as evident from their responses to the course evaluation. © 2012 Published by Elsevier Ltd. Source

Vargas-Martinez A.,ITESM | Ayala-Arnez M.A.,Administradora Boliviana de Carreteras
Water Science and Technology

The objective of this research was to include ozonation prior to an activated sludge treatment and investigate the effect on the nitrogen species, their fate and the consequences of this oxidation upon the biomass. Three parallel treatment systems were used: the base system, where feed went directly to the activated sludge reactor, and two others, where the influent was ozonated at two different dosages, 15 and 25 mg/L of influent, prior to the biological reactors. The results from the ozonation chamber show a high oxidation capacity of the entering ammonia and organic nitrogen, proportional to the ozone dose. The oxidation product was nitrate. No de-nitrification was expected because a high oxygen concentration (4 mg/L) was maintained in the reactors. The reactors receiving ozonated influent showed a lower assimilation of nitrogen by the biomass. The sludge nitrogen content resulted in 11, 9.3 and 7.4% dry-weight corresponding to no-ozone, low ozone and high ozone dosages, respectively. In spite of the lower ammonia available in the ozonated flows, the corresponding reactors showed a higher specific nitrification rate. The ozonated system also performed better in terms of chemical oxygen demand (COD) and biochemical oxygen demand (BOD 5) removals, besides showing a higher true biomass yield coefficient. © IWA Publishing 2011. Source

Luna-Aguirre C.M.,Autonomous University of Nuevo Leon | Araiza-Chavez J.,Hospital of Zone no. 6 | Trevino V.,ITESM
Asia-Pacific Journal of Clinical Oncology

Aims: To develop new biomarkers for early detection and to inform effective clinical management of breast cancer. Methods: Real-time polymerase chain reaction was used to profile microRNA (miRNA) in tumor tissue from 50 breast cancer patients using non-tumor breast tissue from each patient as a control. We have focussed on three miRNA; miR-21, miR-125b and miR-191, all of which have been implicated in breast cancer with either proven or predicted target genes involved in critical cancer-associated cellular pathways. Results: Upregulation of miR-21 and miR-191 and downregulation of miR-125b, was found in breast cancer tissue. Combined expression analysis of miR-125b/miR-191 increased sensitivity to 100% and specificity to 94% while miR-21/miR-191 increased to 92% and 100%, respectively. Therefore, combination of two miRNA gives a better prediction than individual miRNA. Conclusions: We could differentiate between breast cancer and adjacent non-tumor breast tissue as a control with a high degree of sensitivity and specificity in the Mexican population using a combined expression analysis of only two miRNA. These observations, although a proof of principle finding at this time, show that a combined expression profile of two miRNA (miR-125b/miR-191 and miR-21/miR-191) can discriminate between breast cancer and non-tumor tissue with high specificity and sensitivity. © 2012 Wiley Publishing Asia Pty Ltd. Source

Lozano R.,University of Leeds | Lukman R.,University of Maribor | Lozano F.J.,ITESM | Huisingh D.,University of Tennessee at Knoxville | Lambrechts W.,Hogeschool University Brussel
Journal of Cleaner Production

In spite of a number of Sustainable Development (SD) initiatives and an increasing number of universities becoming engaged with SD, most higher education institutions (HEIs) continue to be traditional, and rely upon Newtonian and Cartesian reductionist and mechanistic paradigms. As a result many universities are still lagging behind companies in helping societies become more sustainable. This paper analyses the texts of eleven declarations, charters, and partnerships developed for HEIs, which can be considered to represent university leaders' intentions to help improve the effectiveness of Education for Sustainable Development (ESD). The analysis was done against two sets of criteria: (1) the university system, including curricula, research, physical plant operations, outreach and engagement with stakeholders, and assessment and reporting; and (2) the texts' complexity, number of bullet points, and number of words. The analysis was done continuously; whenever a new element was found in a text it was added to the university system (first criteria set) and applied to the analysis of the other texts. In this way, the system was augmented with the following elements: collaborating with other universities; fostering transdisciplinarity; making SD an integral part of the institutional framework; creating on-campus life experiences; and 'Educating-the-Educators'. The authors of the paper propose that for universities to become sustainability leaders and change drivers, they must ensure that the needs of present and future generations be better understood and built upon, so that professionals who are well versed in SD can effectively educate students of 'all ages' to help make the transition to 'sustainable societal patterns'. In order to do so, university leaders and staff must be empowered to catalyse and implement new paradigms, and ensure that SD is the 'Golden Thread' throughout the entire university system. © 2011 Elsevier Ltd. All rights reserved. Source

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