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Isparta, Turkey

Okur M.,Pediatrics | Kaya E.,Duzce University | Erbas M.,Canakkale Onsekiz Mart University | Kutlucan L.,State Hospital of Duzce | Sahan L.,State Hospital of Isparta
International Journal of Clinical and Experimental Medicine | Year: 2013

Purpose: The present report was focused on clinical advantages of sedoanalgesia in the pediatric outpatient surgical cases. Method: Sedoanalgesia has been used to sedate patients for a variety of pediatric procedures in our department between 2007 and 2010. This is a retrospective review of 2720 pediatric patients given ketamine for sedation with midazolam premedication. Ketamine was given intravenously (1-2 mg/kg) together with atropine (0.02 mg/kg) and midazolam (0.1 mg/kg) + a local infiltration anesthetic 2 mg/kg 0.5% bupivacaine hydrochloride. Result: Median age of the patients included in the study was 5.76 ± 2.12 (0-16 years). The main indications for ketamine include circumcision (69%), inguinal pathologies (inguinal hernia (17%), orchidopexy (2.68%), hydrocele (3.38%), hypospadias (1.94%), urethral fistula repair (0.33%), urethral dilatation (0.25%), and other conditions. All of our patients were discharged home well. In this regard, we have the largest group of patients ever given ketamine. Conclusion: Sedoanalgesia might be used as a quite effective method for daily surgical procedures in children.


Ketenci I.,Erciyes University | Senturk M.,State Hospital of Bursa | Yuksel F.,State Hospital of Isparta
European Journal of General Medicine | Year: 2014

Aim of this study is to carry out a rhinomanometric assessment for the impact of altitude variation (1050-2215m) on nasal airflow. First of all, rhinomanometry standard values were specified in 100 healthy people (0.53 on the left; 0.55 Pa/cm3/sec on the right). 42 people were enrolled into the study. Nasal resistance was calculated for Group 1 when ascending from 1050m to 2215m and for Group 2 when descending from 2215m to 1050m. Nasal resistances and total nasal resistances were compared. Mean nasal resistances were determined as 0.54 Pa/cm3/sec on the right and 0.54 Pa/cm3/sec on the left for Group 1 and as 0.52 Pa/cm3/sec on the right and 0.59 Pa/cm3/sec on the left for Group 2. Altitude variation in Group 1 and 2 was detected to have no statistically significant effects on right and left nasal resistances. No variation in total resistance was determined either. Although,Altitude variation from 1050 m to 2215 m or from 2215 m to 1050 m does not affect the nasal resistance in this study, due to the many factors that affect the physiology of the nose at high altitude a decisive conclusion can not be said. multi-factorial studies are needed.


Yavuz L.,Suleyman Demirel University of Turkey | Aynali G.,Suleyman Demirel University of Turkey | Aynali A.,State Hospital of Isparta | Alaca A.,State Hospital of Afyon | And 2 more authors.
Journal of International Medical Research | Year: 2012

OBJECTIVE: To determine the effect of immunoglobulin (Ig)M-enriched Ig therapy on mortality rate and renal function in sepsis-induced multiple organ dysfunction syndrome (MODS), using the Acute Physiology and Chronic Health Evaluation II (APACHE II) score. METHODS: Retrospective study of patients with sepsis-induced MODS treated with standard antibiotic plus supportive therapy (control group) or IgM-enriched Ig therapy adjuvant to control group therapy (IVIg group). Total length of stay in the intensive care unit (ICU), overall mortality rate and 28-day case fatality rate (CFR), as well as APACHE II scores and renal function parameters at day 1 and day 4 of therapy, were recorded. RESULTS: A total of 118 patients were included (control group, n = 62; IVIg group, n = 56). In both groups, day 4 APACHE II scores decreased significantly compared with day 1 scores; the effect of treatment on renal function was minimal. Length of ICU stay, overall mortality rate and 28-day CFR were significantly lower in the IVIg group compared with the control group. CONCLUSIONS: Adding IgM-enriched Ig therapy to standard therapy for MODS improved general clinical conditions and significantly reduced APACHE II scores, overall mortality rate and 28-day CFR, although effects on renal function were minimal. © 2012 Field House Publishing LLP.

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