Nechab M.,Aix - Marseille University |
Besson E.,Aix - Marseille University |
Campolo D.,Aix - Marseille University |
Perfetti P.,Aix - Marseille University |
And 4 more authors.
Chemical Communications | Year: 2011
Mesoporous silica grafted with a tertiary amine was used as a basic nanocatalyst to promote in confined medium the enantioselective cascade rearrangement of enediynes based on the phenomenon of memory of chirality; the multi-substrates recyclable catalytic reagent could easily be recovered by simple filtration, and reused without any decrease in activity even when changing the solvent. © 2011 The Royal Society of Chemistry.
Mondal S.,CNRS Institute of Radical Chemistry |
Nechab M.,CNRS Institute of Radical Chemistry |
Vanthuyne N.,ISM2 |
Bertrand M.P.,CNRS Institute of Radical Chemistry
Chemical Communications | Year: 2012
The tandem Crabbé homologation-radical rearrangement of terminal enediynes leads, in a one-pot procedure, to the enantioselective synthesis of six- and seven-membered ring α-aminoesters bearing a quaternary stereocenter based on the phenomenon of memory of chirality. This journal is © The Royal Society of Chemistry 2012.
Albalat-Serradeil M.,Clariant |
Primazot G.,Clariant |
Wilhelm D.,Clariant |
Vallejos J.-C.,ISM2 |
And 2 more authors.
Amino Acids | Year: 2012
The first successful resolution of rac-a-aminoacetals via diastereoisomeric salt formation with optically pure N-protected aminoacids is reported. The absolute configuration assignment of a-aminoacetal enantiomers is performed by an entirely non-racemizing chemical correlation method involving N-protection and a new efficient hydrolysis step followed by a reduction of the resulting N-protected a-aminoaldehyde intermediates. A racemization method of optically enriched a-aminoacetals is exemplified to allow valorisation of both enantiomers. © Springer-Verlag 2011.