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Severo C.B.,Mycology Laboratory | Bello A.G.D.,Federal University of Rio Grande do Sul | de Mattos Oliveira F.,Mycology Laboratory | Guazzelli L.S.,Mycology Laboratory | And 4 more authors.
Mycopathologia | Year: 2013

Paracoccidioidomycosis (PCM) is an endemic disease restricted geographically to Latin America. Brazil accounts for about 80 % of the reported cases, and lungs are most frequently affected. A suggestive radiograph of PCM may only be seen late in the course of the disease. At the beginning, it mimics tuberculosis. On the other hand, pleural effusion on rare occasions has been reported in PCM. For this reason, we report two cases with such uncommon manifestation. Our first patient presented pleural effusion probably caused by PCM (a previously unreported cause of lung mass accompanied by effusion); the second with proved pleural effusion due to PCM. A systematic review of the literature was done. © 2013 Springer Science+Business Media Dordrecht. Source

de Moraes Costa G.,Federal University of Health Sciences, Porto Alegre | Soibelman M.,Irmandade Santa Casa de Misericordia de Porto Alegre ISCMPA | Zanchet D.L.,Federal University of Santa Maria | de Moraes Costa P.,Federal University of Santa Maria | Salgado C.A.I.,Federal University of Health Sciences, Porto Alegre
Jornal Brasileiro de Psiquiatria | Year: 2012

Objective: In this study we aim to characterize a sample of 85 pregnant crack addicts admitted for detoxification in a psychiatric inpatient unit. Method: Cross-sectional study. Sociodemographic, clinical, obstetric and lifestyle information were evaluated. Results: Age of onset for crack use varied from 11 to 35 years (median = 21). Approximately 25% of the patients smoked more than 20 crack rocks in a typical day of use (median = 10; min-max = 1-100). Tobacco (89.4%), alcohol (63.5%) and marijuana (51.8%) were the drugs other than crack most currently used. Robbery was reported by 32 patients (41.2%), imprisonment experience by 21 (24.7%), trade of sex for money/drugs by 38 (44.7%), home desertion by 33 (38.8%); 15.3% were positive for HIV, 5.9% for HCV, 1.2% for HBV and 8.2% for syphilis. After discharge from the psychiatric unit, only 25% of the sample followed the proposed treatment in the chemical dependency outpatient service. Conclusion: Greater risky behaviors for STD, as well as high rates of maternal HIV and Syphilis were found. Moreover, the high rates of concurrent use of other drugs and involvement in illegal activities contribute to show their chaotic lifestyles. Prevention and intervention programs need to be developed to address the multi-factorial nature of this problem. Source

Leon R.M.,Federal University of Health Sciences, Porto Alegre | Ranzi A.D.,Federal University of Health Sciences, Porto Alegre | Fardin G.S.,Federal University of Health Sciences, Porto Alegre | Keitel E.,Irmandade Santa Casa de Misericordia de Porto Alegre ISCMPA | And 3 more authors.
Jornal Brasileiro de Patologia e Medicina Laboratorial | Year: 2016

Introduction: Human papillomavirus (HPV) is the main cause of cervical cancer, and immunosuppression is recognized as a risk factor for HPV infection and its persistence. After renal transplantation, immunosuppressive agents are used to prevent rejection, but predispose recipients to chronic infections and malignancies. Objective: This study aimed to verify, based on urinary cytology (UC), the prevalence of HPV in immunosuppressed kidney transplant patients. Material and method: In this cross-sectional study, the population was composed of kidney transplant patients that had undergone routine UC from August 2012 to August 2014. Results: There were 2,305 urine cytopathological tests. Thirteen patients with presence of koilocytes in such examination were observed. Therefore, the relative frequency of patients with HPV detected in urine was 0.56%. In the interval until the first post-transplant year, 10 (76.92%) patients presented koilocytes (p < 0.0001) in the UC. The dosages of immunosuppressive agents until the first post-transplant consultation, which showed correlation with the period between transplantation and the first UC test with the presence of koilocytes (p < 0.0001), were prednisone 10.5-20 mg/day, mycophenolate sodium 901-1,440 mg/day, and tacrolimus 4.5-12 mg/day. Conclusion: This study showed immunosuppression as an important risk factor for infection by HPV or its reactivation. Screening UC tests after transplantation may evidence HPV infection. Source

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