Boulogne-billancourt, France
Boulogne-billancourt, France

Ipsen is a French pharmaceutical company headquartered in Paris, France. It primarily develops and markets medications used in oncology, endocrinology and the treatment of neuromuscular disorders. It is publicly traded on the Euronext Paris as part of the SBF 120 index. Wikipedia.

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Patent
Ipsen | Date: 2016-10-24

A process for the large-scale synthesis of a therapeutic peptide using solid-phase Fmoc-chemistry.


A composition, medicament or use, comprising or consisting of botulinum toxin type A2 and a surfactant, having one or more or all of the characteristics selected from the group consisting of :(a) a much longer duration of action;(b) a much faster rate of onset of muscular paralysis;(c) a significantly greater intramuscular safety margin;(d) a selective action on inhibition of skeletal muscle contraction;(e) a selective action on inhibition of pain-related (nociceptive) nerve cell function, wherein each characteristic is determined comparative to the same characteristic effect of botulinum toxin type A1.


The present invention relates to a parenteral sustained and controlled release semisolid formulation comprising an oligomer end-capped and an active substance without any supplementary viscosity reducing agent or excipient.


The present invention relates to at least one botulinum neurotoxin for treatment or prevention of pain associated with diabetic neuropathy wherein said botulinum neurotoxin is prepared for local administration, wherein the local administration is not in the central nervous system (CNS), and wherein pain is treated at a site distant to the site of administration.


A system and method for facilitating the maintenance of an industrial heat treating furnace are disclosed.


The invention provides methods for producing soluble di-chain BoNT/A protein.


Patent
Ipsen | Date: 2016-09-30

Pharmaceutical compositions, in particular, compositions comprising growth hormone (GH) and insulin-like growth factor (IGF-1) which are stable at a desirable pH without aggregation formation, and processes for preparing such compositions.


The present invention relates to a method of treating a transient impairment of the motility of the gastrointestinal system resulting from postoperative ileus in a patient wherein said method includes the step of administering a therapeutically effective amount of a peptidyl analog of ghrelin to said patient.


An aqueous pharmaceutical composition comprising a peptide and one or more water-soluble or water-dispersible gelling agents.


The present invention relates to the use of Lys-C for proteolytically processing a single-chain botulinum neurotoxin serotype B (BoNT/B) or F (BoNT/F) by hydrolysis to produce di-chain botulinum neurotoxin serotype B (BoNT/B) or F (BoNT/F), as well as related methods.

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