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Kolkata, India

Bain J.,IPGMEandR | Lal S.,E.M.A.R.C. | Baghel V.,Ss Medical College | Yedalwar V.,Ss Medical College | And 2 more authors.
Journal of Natural Science, Biology and Medicine | Year: 2014

Introduction: Burn injuries are a serious public health problem. In our study we have identified different epidemiological factors based on 10 years of our experience at a burn unit in central India and recommend some strategies to prevent burn injuries. Materials and Methods: This is a retrospective analysis (2001-2010) of database from burn unit of S.S. Medical College, Rewa, India. Results: 2499 patients with burn injury were analysed. 66.8% and 38.2% patients were females and males respectively, with a median age of 25 years. Flame (80.1%) was most common cause, home (96%) was most common place, traditional Indian stove (28.8%), kerosene lamp (26.7%), hot liquid (12.2%) and kerosene stove (10.4%) were common causes. Median Total Body Surface Area (TBSA) burn was 40.0%; females had significantly greater (P < 0.001) burn than males (median 50% vs 26.0%). High mortality (40.3%) seen; female sex (OR 3.22, 95% CI 2.65-3.92); young age (15-29 year) (OR 3.48, 95% CI 2.45-4.94); flame burn (OR 12.9, 95% CI 1.69-98.32); suicidal burn OR 6.82 95%CI 4.44-10.48) and TBSA > 76% (OR 3099, 95%CI 1302-7380) were significant risk factors for death. Median hospital stays was 8 days; shorter hospital stays seen among TBSA burn > 76% (2 days), suicidal intent (4 days), and those who expired (4 days). Septicemia (45.8%) and burn shock (41%) were the major cause for death. Conclusions: Cooking and lighting equipments are major cause of burn injury among females and young age group. Equipment modification to improve safety features and public awareness programs are necessary to reduce burn incidents. Source

Mukhopadhyay B.,R G Kar Medical College | Khan Md.S.,R G Kar Medical College | Uz Zaman Md.S.,IPGMEandR
Biomedicine (India) | Year: 2013

Introduction: Prevalence of Diabetes Mellitus (DM) is increasing gradually particularly in India. DM leads to secondary pathophysiological changes including those of respiratory system. Biochemical changes result in impaired collagen and elastin cross-linkages leading to reduced strength and elasticity of connective tissues. In the lungs it leads to thickened alveolar and capillary lamina leading to reduced pulmonary elastic recoil and lung volumes affecting ventilation. Aim: Current study was done to evaluate various lung function tests subclinical pulmonary dysfunction in cases of DM at an early stage for prompt intervention to reduce morbidity and mortality. Materials and Methods: Sixty diabetic patients and sixty non-diabetic subjects were selected as cases and controls and studied at RG Kar Medical College for FVC-PP, FEV1-PP, FEV1/FVC-PP, PEFR-PP, DLCO, DL/VA, FEF-PP. Results: All except FEV1/FVC-PP showed significant reduction in patients with DM. Source

Maitra S.,IPGMEandR | Sen S.,IPGMEandR | Pal S.,MGM Medical College
Egyptian Journal of Anaesthesia | Year: 2013

Perioperative management of peripartum cardiomyopathy patients posted for emergency caesarean section is a unique challenge to the anaesthesiologist. We are hereby reporting a case of peripartum cardiomyopathy posted for emergency caesarean section. A 23 year old lady with a 35 weeks pregnancy was admitted in our hospital with increasing breathlessness. Subsequently, she was diagnosed as a case of peripartum cardiomyopathy. She was posted for an urgent LUCS. After a rapid initial stabilization, she received combined spinal fentanyl with titrated epidural bupivacaine to achieve surgical anaesthesia. Apart from routine ASA monitors, CVP and IBP were monitored during the surgery. Hemodynamic perturbations were insignificant during surgery, and the postoperative period was uneventful. Key Messages: Combined spinal opioid with carefully titrated epidural anaesthesia is a safe and effective technique for anaesthetic management of peripartum cardiomyopathy posted for LUCS. © 2013 Production and hosting by Elsevier B.V. on behalf of Egyptian Society of Anesthesiologists. Source

Ghosh A.,Rg Kar Medical College And Hospital | Ghosh B.,IPGMEandR | Pain S.,Rg Kar Medical College And Hospital | Pande A.,Rg Kar Medical College And Hospital | And 3 more authors.
Indian Journal of Rheumatology | Year: 2011

To investigate the relationship among DAS28, CDAI and HAQ-DI in early rheumatoid arthritis (RA) patients. It was a prospective study on 61 consecutive DMARD naive early RA patients attending the outpatient department of a tertiary care hospital in eastern India. DAS28, CDAI and HAQ-DI were calculated at the initial visit. They were put on DMARD therapy as per protocol with categorization of disease activity as per the CDAI values. DAS28, CDAI and HAQ-DI were again calculated after 3 months. Statistical analysis was carried out. There was a significant correlation among HAQ-DI, DAS28 and CDAI values. HAQ-DI showed significant correlation with the individual variables used in CDAI and DAS28. These observations were noted both in the initial and after 3-month follow-up values. There was significant agreement between the disease activity categories obtained by CDAI and DAS28 cut-off levels. Combination DMARD therapy based on ACR 2008 recommendations resulted in significant improvement in disease activity and functional disability. We can assess the disease activity in the patients by recording the HAQ-DI, at least in cases of early RA. Both DAS28 and CDAI are equally useful in assessing the disease activity of RA. These facts become important as it suggests that laboratory values do not remain absolutely essential in the assessment of the patients. These findings are especially important in a fund-stricken health system in developing countries like India. © 2011 Indian Rheumatology Association. Source

Sinha S.,IPGMEandR | Mukherjee M.,RGKMCandH | Chatterjee S.,NRSMCandH | Vijay M.,IPGMEandR | And 2 more authors.
Anaesthesia, Pain and Intensive Care | Year: 2012

Aim: To compare the efficacy of paravertebral block with ropivacaine or ropivacaine plus dexmedetomidine for relief of post operative pain in patients undergoing unilateral renal surgeries. Methodology: Sixty adult patients of ASA I & II, undergoing unilateral renal surgery, were included in this prospective, randomized study. After placing the catheter in T12-L1 paravertebral space, block was randomly activated either by 18 ml of ropivacaine 0.25% (Group I) or by 18 ml of ropivacaine 0.25% plus 1μg/kg dexmedetomedine (Group II). General anaesthesia was instituted in all patients using a standardised technique. After recovery from GA, pain was assessed by VAS. The patients were administered ! rst top up dose through paravertebral route as soon as VAS score exceeded 3 and time was noted duration of analgesia. Total requirement of ropivacaine in 24 hours was also noted. Result: Mean duration of analgesia was longer in Group II (324.4 ± 56.35 min) as compared to Group I (149.2 ± 30.64 min) (p < 0.05). Mean total consumption of ropivacaine was 84 ± 14.12 mg in Group II and 120 ± 15.26 mg in Group I (p < 0.05). Conclusion: Addition of dexmedetomidine to local anaesthetic agent ropivacaine signi! cantly prolongs the duration of analgesia in paravertebral blocks. Source

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