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News Article | June 19, 2008
Site: gigaom.com

If all this attention to cleantech was starting to make you feel all warm and fuzzy, there’s a report out this week that could kill that glow. The oceans are warming and the sea levels are rising faster than previously predicted. According to a group of researchers, that 2007 report from the Nobel Peace Prize winning Intergovernmental Panel on Climate Change actually underreported the rise in both ocean temperature and sea levels from 1961 to 2003 by a very significant 50 percent. Oops. The new report was created by researchers at Lawrence Livermore National Laboratory, the Center for Australian Weather and Climate Research, and the Antarctic Climate and Ecosystems Cooperative Research Center. The researchers say they have corrected for “systematic biases” in standard ocean observation techniques and also used statistics to fill in missing information. Sea levels can rise by both thermal expansion of the heated seas and melting bodies of ice. The new report found that thermal expansion caused a greater rise in sea levels than the IPCC had previously reported — 0.53 millimeter per year, compared with 0.32 mm per year, according to the Agence France-Presse. The results are being reported in this week’s Nature. In the grand scheme of things this means that we just need all these technologies scaled up faster if we’re ever going to find a global fix for climate change.

Mallo M.,Spanish Haematological Cytogenetics Working Group | Mallo M.,Autonomous University of Barcelona | Mallo M.,Spanish MDS Registry Group | Cervera J.,Spanish Haematological Cytogenetics Working Group | And 52 more authors.
Leukemia | Year: 2011

This cooperative study assessed prognostic factors for overall survival (OS) and risk of transformation to acute myeloid leukemia (AML) in 541 patients with de novo myelodysplastic syndrome (MDS) and deletion 5q. Additional chromosomal abnormalities were strongly related to different patients characteristics. In multivariate analysis, the most important predictors of both OS and AML transformation risk were number of chromosomal abnormalities (P0.001 for both outcomes), platelet count (P0.001 and P0.001, respectively) and proportion of bone marrow blasts (P0.001 and P0.016, respectively). The number of chromosomal abnormalities defined three risk categories for AML transformation (del(5q), del(5q)1 and del(5q)2 abnormalities) and two for OS (one group: del(5q) and del(5q)1; and del(5q)2 abnormalities, as the other one); with a median survival time of 58.0 and 6.8 months, respectively. Platelet count (P0.001) and age (P0.034) predicted OS in patients with 5qsyndrome. This study demonstrates the importance of additional chromosomal abnormalities in MDS patients with deletion 5q, challenges the current 5qsyndrome definition and constitutes a useful reference series to properly analyze the results of clinical trials in these patients. © 2011 Macmillan Publishers Limited All rights reserved.

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