The International University of Japan is a private university located in Minami-Uonuma city in Niigata Prefecture, Japan.IUJ is the first graduate school in Japan, and one of the few Japanese universities which offers all courses in English. It was founded in 1982, primarily to train global leaders effective in the globalized world, be it in business, government, world organizations, or the non-profit sector. IUJ offers Master's degrees in International Development, Economics, Public Management, International Peace Studies and International Relations, as well as an MBA in business administration and an E-business degree. IUJ is fully approved and accredited by the Ministry of Education, Japan. The IUJ Business school is consistently ranked among the top schools in the world by leading business and education publications. The Public Management program, too, was recently noted among the best. Some of the rankings are noted below.The IUJ campus has an extremely diverse student body, with students from all over the world. In any given academic year there are students from about 50 countries. This diversity is accentuated by the fact that there are only 330 total students on campus. The diversity was celebrated as part of IUJ's 25th Anniversary through a Guinness World Record record breaking attempt - "The most nationalities in a sauna ".IUJ provides a balanced education through the discovery of Japanese and other world cultures. There are many chances to improve skills in cross-border communications, leadership, judgment and decision-making in internationally diversified groups. The spirit for volunteering too is encouraged. To celebrate its international characteristics, IUJ hosts an "International Festival" during the spring term at which students showcase their respective cultures and cuisine for the local community.IUJ is near ski and hot spring resorts in Niigata prefecture. Its location outside of major cities such as Tokyo enhances its academic excellence and strong student friendship bonding. Wikipedia.
Yoshida H.,International University of Japan |
Yabuno A.,International University of Japan |
Fujiwara K.,International University of Japan
Drug Design, Development and Therapy | Year: 2015
Bevacizumab is the first molecular-targeted agent to be used for the treatment of ovarian cancer. Bevacizumab is a humanized monoclonal antibody targeting vascular endothelial growth factor. Two randomized Phase III trials evaluated the combination of bevacizumab plus standard cytotoxic chemotherapy for first-line treatment of advanced ovarian cancer. Additional Phase III trials evaluated bevacizumab combined with cytotoxic chemotherapy in platinum-sensitive and platinum-resistant recurrent ovarian cancer. All these trials reported a statistically significant improvement in progression-free survival but not in overall survival. Furthermore, bevacizumab effectively improved the quality of life with regard to abdominal symptoms in recurrent ovarian cancer patients. Bevacizumab is associated with adverse events not commonly observed with cytotoxic agents used to treat gynecological cancers, such as hypertension, bleeding, thromboembolism, proteinuria, delayed wound healing, and gastrointestinal events. However, most of these events can be adequately managed by gynecologists. The clinical trial results with bevacizumab have supported its recent approval in Europe and the United States as a treatment for ovarian cancer. This review presents the latest evidence for bevacizumab therapy of ovarian cancer and describes selection of patients for personalized treatment. © 2015 Yoshida et al.
Fujita-Jimbo E.,International University of Japan |
Fujita-Jimbo E.,Jichi Medical University |
Momoi T.,International University of Japan
Neuroscience Letters | Year: 2014
The R553H mutation has been found in the FOXP2 gene of patients with speech-language disorder. Foxp2(R552H) knock-in (KI) mice exhibit poor dendritic development of Purkinje cells in the cerebellum and impaired ultrasonic vocalization (USV), which is related to human speech and language; compared with wild-type mice, heterozygous Foxp2(R552H)-KI pups exhibit the reduced number of whistle-type USVs and the increased short-type ones, while homozygous pups exhibit only click-type USVs but no whistle-type or short-type ones. To make clear the relationship between the role of Foxp2 in the cerebellum and whistle-type USVs activity, we prepared transgenic (Tg) mice specifically expressing human FOXP2-myc in cerebellum (Pcp2-FOXP2-myc-Tg mice) by using purkinje cell protein-2 (Pcp2) promoter. FOXP2-myc expression in the cerebellum increased the relative numbers of whistle-type USVs in the heterozygous Foxp2(R552H)-KI pups and recovered their USVs but did not in the homozygous ones. Foxp2 in the cerebellum may pertain to the brain network engaged in whistle-type USVs activities including modification, but not their production. There may be common molecular contribution of Purkinje cells to human FOXP2-mediated speech-language and mouse Foxp2-mediated USVs. © 2014 Elsevier Ireland Ltd.
Oh S.,International University of Japan
Integrative Psychological and Behavioral Science | Year: 2017
This study analyzes a process through which university students in Japan and South Korea come to understand the culture of the other country by exchanging comments on a documentary movie “ANNYON SAYONARA (Hello and Goodbye)” which relates to the Asia-Pacific War and Korean colonial rule by Japan. The approach to understand other cultures through movies is called the “Round Table Cinema Method” and is a method whereby individuals with different cultural backgrounds talk about the same movie to discuss “gaps,” “sense of incongruity,” and “internal conflicts” that arise. Through exchanging comments with each other, both countries’ students damaged each other, but this eventually changed and the viewpoint and feeling of the partner became better understood. © 2017, Springer Science+Business Media New York.
Moore D.,Carleton University |
Hirai H.,International University of Japan
Theoretical Criminology | Year: 2014
We draw on a field study of three drug treatment courts to show that responsibilization strategies create a paradox of bulimic exclusion and empowerment for individual subjects. By theorizing three different subjectivities emerging from our research sites (outcasts, performers and true believers), we show how subjects of intervention actively work to negotiate their own experiences of responsibilization. © The Author(s) 2014.
News Article | November 1, 2016
TOKYO, Nov 2, 2016 /PRNewswire/ -- Soramitsu Co., Ltd. (Co-CEOs: Makoto Takemiya, Ryu Okada; hereafter, Soramitsu) developed an open source distributed ledger (i.e., blockchain ) platform, Iroha, and submitted it to the Linux Foundation's Hyperledger Project as an incubation sub-project. Iroha was accepted into incubation status and will join IBM's Fabric and Intel's Sawtooth Lake as the third distributed ledger project with incubation status. Iroha is a new distributed ledger platform that was developed from scratch and proposed to the Hyperledger Project by Soramitsu, NTT Data, and Israeli startup Colu, among others, on September 26th, 2016, in Geneva, Switzerland. On October 13, 2016, Iroha was officially accepted into incubation status. Iroha aims to provide a secure and decentralized data management platform for financial institutions, as well as many other fields, such as healthcare and logistics. Using the custom "Sumeragi" consensus algorithm, Iroha aims to provide consistent transaction finality within 2 seconds, making the platform useful for many real-world scenarios. To provide high throughput scaling to thousands of transactions per second, Iroha uses UDP multicast and C++ for data processing. To explore use cases and work to increase the viability of the Iroha platform, Sompo Holdings Inc. is working with Soramitsu to create derivatives on top of the distributed ledger. The University of Tokyo, the University of Aizu, and the Center for Global Communications (GLOCOM) of the International University of Japan, are also working with Soramitsu to study the economics of local currencies and their effects on regional development. Joint research in the area around Aizu, in Fukushima Prefecture, Japan, will include experiments using local currencies running on Iroha. In addition, with Rakuten Securities, Inc., Soramitsu has announced that they are working together to develop a KYC  system using blockchain technology. Mizuho Information & Research Institute, Inc., is also exploring the use of Iroha. Soramitsu is committed to the development of blockchain systems that can contribute to society by providing safe and secure data management. Partners who want to contribute to Iroha and also work with Soramitsu on creating services, especially a digital identity KYC service for financial institutions, are invited to contact Soramitsu. Iroha is open source and anyone can contribute to it at http://github.com/hyperledger/iroha. -- Simple architecture, easy to understand and to develop for -- Distributed ledger technology and smart contract platform -- New Byzantine Fault Tolerant consensus algorithm, called Sumeragi -- Java-based smart contracts -- Simple issuance and transfer of digital assets, such as currencies and points -- Mobile and web application development platforms Expected use-cases for Iroha (among others) -- Settlement -- Contract management -- Securities clearing -- Development of financial products such as insurance -- Supply chain management -- Smart grid -- Trade finance -- KYC  -- Notary and time stamp services -- Sharing economy -- Healthcare -- IoT About the use of trademarks All company, product names, and trademarks, are the property of their respective owners. Soramitsu is a Japanese startup founded in February of 2016, focusing on blockchain and distributed ledger technology. Currently, Soramitsu is developing a platform for managing digital identities. Since identity management is required for many disparate services, building a digital identity platform on blockchain technology is an important way to manage identity for applications involving many different players. Soramitsu is a member of the Linux Foundation's Hyperledger Project. The Hyperledger Project aims to create global standards for blockchain and distribution ledger technology, with the aim of providing practical solutions for businesses and meeting the needs of society. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/soramitsus-iroha-distributed-ledger-platform-accepted-by-the-linux-foundations-hyperledger-project-as-the-third-platform-with-incubation-status-300355032.html
Yasuda M.,International University of Japan
Journal of Obstetrics and Gynaecology Research | Year: 2014
Developments in immunohistochemistry, which are closely linked with the advances in the analyses of genetic abnormalities and their associated molecular disorders as early and late histogenetic events, have contributed greatly to the improvement of pathological diagnostic confirmation and validation. Immunohistochemistry has also generated great benefit to the innovation of therapeutic strategies for various kinds of cancers. In this article, the three representative histological types of corpus cancer, namely, endometrioid adenocarcinoma, serous adenocarcinoma and clear cell adenocarcinoma, will be histologically approached in association with their immunohistochemical profiles as well as genetic disorders. First, the focus will be on 'Conventional/prototypic features,' followed by 'Controversy over conventional histological subclassification,' and subsequently 'Tumorigenesis and re-subclassification.' © 2014 The Authors.
Oi S.,International University of Japan
Child's Nervous System | Year: 2011
Objective: Hydrocephalus is a complex pathophysiology with disturbed cerebrospinal fluid (CSF) circulation. There are numerous numbers of classification trials published focusing on various criteria, such as associated anomalies/underlying lesions, CSF circulation/intracranial pressure patterns, clinical features, and other categories. However, no definitive classification exists comprehensively to cover the variety of these aspects. The new classification of hydrocephalus, "Multi-categorical Hydrocephalus Classification" (Mc HC), was invented and developed to cover the entire aspects of hydrocephalus with all considerable classification items and categories. Materials and method: Ten categories include "Mc HC" category I: onset (age, phase), II: cause, III: underlying lesion, IV: symptomatology, V: pathophysiology 1-CSF circulation, VI: pathophysiology 2-ICP dynamics, VII: chronology, VII: post-shunt, VIII: post-endoscopic third ventriculostomy, and X: others. From a 100-year search of publication related to the classification of hydrocephalus, 14 representative publications were reviewed and divided into the 10 categories. Results and discussion: The Baumkuchen classification graph made from the round o'clock classification demonstrated the historical tendency of deviation to the categories in pathophysiology, either CSF or ICP dynamics. Conclusion: In the preliminary clinical application, it was concluded that "Mc HC" is extremely effective in expressing the individual state with various categories in the past and present condition or among the compatible cases of hydrocephalus along with the possible chronological change in the future. © 2011 Springer-Verlag.
Igari N.,International University of Japan
Telematics and Informatics | Year: 2014
The paper presents a comparative analysis of two advanced ICT nations, Japan and Denmark. While Japan is very advanced with respect to its telecommunications infrastructure, Denmark has come further than Japan regarding the use of ICT infrastructures. This paper compares Denmark, a leader in ICT usage, and Japan, which lags in that regard, analyzes differences in institutions, technologies, and services offered, and examines factors contributing to the success of Denmark in promoting ICT usage from a Japanese perspective. Strong governmental leadership, and common techno-infrastructure such as personal ID and digital signature that serve different systems, and user-orientation of service design are the characteristics of Danish efforts absent in Japan. © 2013 Elsevier Ltd. All rights reserved.
Ito K.,International University of Japan
Clinical nuclear medicine | Year: 2011
Hemochromatosis is an iron storage disorder with progressive and massive deposition of iron in the parenchymal cells of various organs. A 72-year-old woman with rheumatoid arthritis diagnosed with secondary hemochromatosis underwent F-18 fluorodeoxyglucose (FDG) positron emission tomography(PET)/computed tomography (CT) to search for malignancy. F-18 FDG PET/CT incidentally showed homogeneous and high FDG uptake (mean SUV, 4.8) in the liver with high density. FDG uptake seemed to be reflected by the functional abnormality of liver. Hemochromatosis should be considered when making a diagnosis of homogeneous high F-18 FDG uptake in liver with high density on CT image.
Osawa A.,International University of Japan |
Maeshima S.,International University of Japan |
Tanahashi N.,International University of Japan
Cerebrovascular Diseases | Year: 2013
Background and Purpose: The water-swallowing test (WST) is frequently used in clinical practice as a functional assessment to detect aspiration and prevent pneumonia. It is a standardized test used all over the world, but the amount of water given varies depending on the examiner. Furthermore, there are very few reports on the simultaneous performance of the WST and videofluorography (VF). This study compared the amount of swallowed water to investigate the reliability of WST to exclude aspiration following acute stroke. Methods: We assessed 111 stroke patients (65 men and 46 women) with suspected dysphagia/difficulty in swallowing and performed VF upon obtaining consent from the patients and their families. Patients were aged between 20 and 98 years (65.6 ± 13.4 years); 64 had cerebral infarction, 26 cerebral hemorrhage, 13 subarachnoid hemorrhage, and 8 had other cerebrovascular disease. The time from stroke onset to VF was 16.6 ± 10.3 days (range, 2-55). WSTs using 5, 10, 30, and 60 ml and the modified WST (MWST) were performed during VF. Results: We found that the number of instances of choking, cough, wet voice, and aspiration increased with higher amounts of water. The sensitivity and specificity of WST for aspiration ranged from 34.8 to 55.7% and from 78.9 to 93.2%, respectively. The MWST, which used only 3 ml of water, yielded a sensitivity of 55.3% and a specificity of 80.8% for aspiration. There was a positive correlation between the time for one swallow and age, but there was no difference between genders. There was also no connection between clinical findings during WST or the presence of aspiration with the number of swallows, swallowing speed, or time for one swallow. Conclusions: WSTs are not as powerful as VF as a screening instrument in acute stroke. WSTs with more water detected aspiration with greater sensitivity, but there is no justification for overconfidence when investigating aspiration. We recommend using WST as well as VF to investigate swallowing in stroke patients. Copyright © 2013 S. Karger AG, Basel.