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News Article | November 25, 2016
Site: www.prweb.com

The family investing team of Wembly Enterprises, led by Sunil and Jay Kumar, has acquired Bradford Industries, Inc., a Lowell, Massachusetts-­‐based producer of coated fabrics & textiles. Terms of the sale were not disclosed. Bradford produces coated fabrics and synthetic leathers for the automotive industry as well as other consumer and industrial markets. “Bradford has tremendous assets-- in manufacturing, technology and, of course, in people.” said Sunil Kumar. “We are pleased to welcome Bradford’s employees to the Wembly family and we are thrilled to add another producer of coated products to our company.” Kumar is the past President and CEO of International Specialty Products (ISP) and of GAF Materials Corporation and he has led Wembly Enterprises through several successful acquisitions. Jay Kumar, President of Wembly-owned Universal Plastics & Mayfield Plastics will serve as CEO of Bradford. Stephen Olsen, a Wembly Principal and co-investor in the Bradford business, will join Bradford as President. Dick Satin, the retiring President of Bradford, said, “We’re proud of the business that we’ve built at Bradford and we see a great future for our people with the Wembly organization. The business is poised for growth and we think we’ve found the right buyer to help us in realizing the company’s potential.” The Capital Corporation, based in Greenville, SC, served as the exclusive advisor to Bradford Industries on the transaction.


Khosravi E.,Durham University | Musa O.M.,International Specialty Products
European Polymer Journal | Year: 2011

Thermosetting materials have been widely used in a variety of applications but they generally display poor tractability after curing, which limits their use in applications where degradable or re-workable polymers are advantageous. Moreover, recyclability and biodegradability of thermosetting polymer also limit their use in applications where recycling and biodegradation are important. A variety of thermally degradable linkages within thermosetting materials have been studied both in academia and industry to develop re-workable adhesives. This review reports the recent development in thermosetting materials containing thermally breakable linkages that exhibit re-workability as well as potential for recyclability and biodegradability. © 2010 Elsevier Ltd. All rights reserved.


Khosravi E.,Durham University | Iqbal F.,Durham University | Musa O.M.,International Specialty Products
Polymer | Year: 2011

Mono- and di-functional norbornene dicarboximide monomers containing acetal ester groups were synthesised. The ROMP of the di-functional monomer using Grubbs ruthenium first generation initiator at ambient temperature produced crosslinked material. Materials with various crosslink densities were prepared by the ROMP, under the same condition, of mixtures of the mono- and di-functional monomers. The FT-IR spectra clearly showed the presence of an acetal C-O band at 1135 cm-1. The TGA study of the crosslinked materials showed that they are stable to 150 °C and that they exhibit rapid breakdown at about 200 °C, as the result of the thermal decomposition of the acetal ester linkage. FT-IR analysis of the retrieved materials following TGA-MS showed that the intensity of acetal C-O band at 1135 cm-1 was greatly reduced. © 2010 Elsevier Ltd. All rights reserved.


Micke A.,International Specialty Products | Lewis D.F.,International Specialty Products | Yu X.,International Specialty Products
Medical Physics | Year: 2011

Purpose: A new method to evaluate radiochromic film dosimetry data scanned in multiple color channels is presented. This work was undertaken to demonstrate that the multichannel method is fundamentally superior to the traditional single channel method. The multichannel method allows for the separation and removal of the nondose-dependent portions of a film image leaving a residual image that is dependent only on absorbed dose.Methods: Radiochromic films were exposed to 10 10 cm radiation fields (Co-60 and 6 MV) at doses up to about 300 cGy. The films were scanned in red-blue-green (RGB) format on a flatbed color scanner and measured to build calibration tables relating the absorbed dose to the response of the film in each of the color channels. Film images were converted to dose maps using two methods. The first method used the response from a single color channel and the second method used the response from all three color channels. The multichannel method allows for the separation of the scanned signal into one part that is dose-dependent and another part that is dose-independent and enables the correction of a variety of disturbances in the digitized image including nonuniformities in the active coating on the radiochromic film as well as scanner related artifacts. The fundamental mathematics of the two methods is described and the dose maps calculated from film images using the two methods are compared and analyzed.Results: The multichannel dosimetry method was shown to be an effective way to separate out nondose-dependent abnormalities from radiochromic dosimetry film images. The process was shown to remove disturbances in the scanned images caused by nonhomogeneity of the radiochromic film and artifacts caused by the scanner and to improve the integrity of the dose information. Multichannel dosimetry also reduces random noise in the dose images and mitigates scanner-related artifacts such as lateral position dependence. In providing an ability to calculate dose maps from data in all the color channels the multichannel method provides the ability to examine the agreement between the color channels. Furthermore, when using calibration data to convert RGB film images to dose using the new method, poor correspondence between the dose calculations for the three color channels provides an important indication that the this new technique enables easy indication in case the dose and calibration films are curve mismatched. The method permit compensation for thickness nonuniformities in the film, increases the signal to noise level, mitigates the lateral dose-dependency of flatbed scanners effect of the calculated dose map and extends the evaluable dose range to 10 cGy-100 Gy.Conclusions: Multichannel dosimetry with radiochromic film like Gafchromic EBT2 is shown to have significant advantages over single channel dosimetry. It is recommended that the dosimetry protocols described be implemented when using this radiochromic film to ensure the best data integrity and dosimetric accuracy. © 2011 American Association of Physicists in Medicine.


Zhang G.,International Specialty Products | Senak L.,International Specialty Products | Moore D.J.,International Specialty Products
Journal of Biomedical Optics | Year: 2011

Spatially resolved infrared (IR) and Raman images are acquired from human hair cross sections or intact hair fibers. The full informational content of these spectra are spatially correlated to hair chemistry, anatomy, and structural organization through univariate and multivariate data analysis. Specific IR and Raman images from untreated human hair describing the spatial dependence of lipid and protein distribution, protein secondary structure, lipid chain conformational order, and distribution of disulfide cross-links in hair protein are presented in this study. Factor analysis of the image plane acquired with IR microscopy in hair sections, permits delineation of specific micro-regions within the hair. These data indicate that both IR and Raman imaging of molecular structural changes in a specific region of hair will prove to be valuable tools in the understanding of hair structure, physiology, and the effect of various stresses upon its integrity. © 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).


Moroni A.,Glaxo SmithKline CHRandD | Drefko W.,International Specialty Products | Thone G.,FMC BioPolymer
Drug Development and Industrial Pharmacy | Year: 2011

Background: Matrix type, monolithic, dosage forms suitable for controlled release that exhibit pH-dependent behavior are considerably less common than similarly behaving multiparticulated, enterically coated dosage forms, although simpler and less expensive to make. Aim: Evaluate the properties of alginates and alginate-containing systems to produce pH-sensitive, monolithic, controlled release dosage forms that perform acceptably and determine their limits of application in regard with stability, pH and Ca ++ sensitivity, and appropriated rate of release. Method: Mixtures of the ionic gum sodium alginate (Na Alg.) with other gel-forming gums such as propylene glycol alginate (PGA), xanthan, or hydroxypropyl methylcellulose have been evaluated for applicability in the manufacture of controlled release dosage forms with three drugs of different solubility and ionic character. Mixture have been compressed into tablets and tested under a variety of pHs to simulate transit through the GI tract, in the presence of Ca ++, and for stability. Results: These mixtures have been able to sustain drug release for up to 12 hours with acceptable performance going from acidic to alkaline pHs to simulate travel through the GI tract and in the presence of Ca ++. Release rate has been adjusted by selecting a suitable Na Alg./other gum combination at an appropriated ratio. Conclusions: Mixtures of Na Alg. with a number of other gums have been demonstrated suitable to manufacture pH sensitive, matrix-type solid dosage forms with release-controlling properties for up to 12 hours. © 2011 Informa UK, Ltd.


Cheng G.,International Specialty Products | Cullen J.,International Specialty Products | Wu C.-S.,International Specialty Products
Journal of Chromatography A | Year: 2011

Although size exclusion chromatography (SEC) has been used successfully to determine the molecular weight distribution (MWD) of statistical poly[(N-vinyl pyrrolidone)-co-(vinyl acetate)]s [PVPVAs], SEC cannot separate the copolymers according to their chemical composition. In this article, the separation of commercial PVPVAs with varying chemical compositions is reported, by aqueous reversed-phase gradient liquid chromatography (RPLC) using polystyrene-divinylbenzene-based wide pore columns. RPLC-SEC cross-fractionation indicates the presence of molar mass dependant effects during RPLC separation due to broad MWD for the copolymer studied; therefore the width of the RPLC peak could not be associated entirely with chemical composition distribution of the copolymer. Coupling of RPLC with online FTIR spectroscopy reveals the increase of VA content with increasing THF gradient, an indication of interaction mechanism between VA repeating units and the stationary phase for water soluble PVPVAs. Separation of water insoluble PVPVAs and PVAs by the RPLC are possibly based on both interaction and precipitation/redissolution mechanisms. © 2010 Elsevier B.V.


Jachowicz J.,International Specialty Products | McMullen R.L.,International Specialty Products
Journal of Cosmetic Science | Year: 2011

Various types of hair, including white (unpigmented), Piedmont (yellow-colored), blonde, brown, curly black of African origin, straight black of Chinese origin, and chemically processed (bleached) hair, were studied by using fluorescence spectroscopy. Fluorescence measurements were obtained by using a single- or double-grating fluorescence spectrophotometer and a bifurcated fiber optics accessory to measure the spectra directly from the surface of the hair. The results have shown that all types of hair share similar fluorescence characteristics, as recorded by excitation at 290 nm, 320 nm, 350 nm, and 380 nm, with emissions that could be ascribed to chromophores such as tryptophan (Trp), N-formylkynurenine, kynurenine, and 3-hydroxykynurenine. The relative intensities of fluorophore emissions were found to be dependent on factors such as melanin content and the history of UV light or thermal exposure. Trp fluorescence was also found to be dependent upon the state of the hair matrix. Softening of hair keratin by chemical reduction (breakage) of disulfide bonds or by hydration, leads to a 50%-increase in Trp emission intensity. Conversely, stiffening of the hair matrix by re-oxidation of reduced hair with hydrogen peroxide, or drying of wet hair, produces a decrease in fluorescence intensity. The results were interpreted by invoking the behavior of certain enzymes, which demonstrate Trp quenching by neighboring disulfide bonds or by hydrogen bonding with alanine residues, or with certain side-chain amino acids.


Porter S.C.,International Specialty Products | Felton L.A.,University of New Mexico
Drug Development and Industrial Pharmacy | Year: 2010

Background: Polymeric film coatings have been applied to pharmaceutical solids for decorative, protective, or functional purposes. The application process is quite complex, with variables related to the coating formulation, substrate properties, processing parameters, and interactions thereof, all of which can affect product performance. Objective: This article describes a number of experimental techniques used to determine the physical, mechanical, adhesive, thermal, and permeability properties of free and applied films. These analytical tools can be used to optimize product performance, advance our knowledge of the film formation process, and investigate interactions between the coating and the solid surface. Conclusion: Through a better understanding of film-coating processes, the cause of problems that arise during manufacturing, defects observed in the coating, and changes in performance upon subsequent storage may be more quickly and accurately resolved. © Informa UK, Ltd.


Levi K.,Stanford University | Kwan A.,Stanford University | Rhines A.S.,Stanford University | Gorcea M.,International Specialty Products | And 2 more authors.
British Journal of Dermatology | Year: 2010

SummaryBackground Emollient molecules are widely used in skin care formulations to improve skin sensory properties and to alleviate dry skin but little is understood regarding their effects on skin biomechanical properties. Objectives To investigate the effects of emollient molecules on drying stresses in human stratum corneum (SC) and how these stresses are related to SC components and moisture content. Methods The substrate curvature method was used to measure the drying stresses in isolated SC following exposure to selected emollient molecules. While SC stresses measured using this method have the same biaxial in vivo stress state and moisture exchange with the environment, a limitation of the method is that moisture cannot be replenished by the underlying skin layers. This provides an opportunity to study the direct effects of emollient treatments on the moisture content and the components of the SC. Attenuated total reflectance Fourier transform infrared spectroscopy was used to determine the effects of emollient molecules on SC lipid extraction and conformation. Results Emollient molecules resulted in a complex SC drying stress profile where stresses increased rapidly to peak values and then gradually decreased to significantly lower values compared with the control. The partially occlusive treatments also penetrated into the SC where they caused extraction and changes in lipid conformation. These effects together with their effects on SC moisture content are used to rationalize the drying stress profiles. Conclusions Emollient molecules have dramatic effects on SC drying stresses that are related to their effects on intercellular lipids and SC moisture content. © 2010 British Association of Dermatologists.

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