Entity

Time filter

Source Type


Sadeghi M.,University of British Columbia | Mclvor J.,University of British Columbia | Finlayson H.,University of British Columbia | Sawatzky B.,International Collaboration on Repair Discoveries | Sawatzky B.,University of British Columbia
Spinal Cord | Year: 2016

Study design:This was a cross-over efficacy study design.Objective:To determine spasticity differences between static and dynamic standing training in individuals with spinal cord injury (SCI).Setting:Vancouver, Canada.Methods:Ten individuals with SCI who could stand with or without bracing or supports participated in both dynamic and static standing training (one session each, 2 days apart) using a Segway. The primary outcome was spasticity as measured by Visual Analog Scale (VAS), Modified Ashworth Scale (MAS) and electromyography (EMG) of the quadriceps, hamstrings, adductors and gastrocnemius.Results:There was no statistically detectable difference in spasticity between dynamic and static standing training in individuals with SCI as measured by VAS, MAS or EMG, although there was a trend towards decreased spasticity after the dynamic training.Conclusion:There is no significant difference in spasticity outcomes between static and dynamic standing training on a Segway for individuals with SCI.Sponsorship:This research was funded by Natural Sciences and Engineering Research Council of Canada and International Collaboration on Repair Discoveries. © 2016 International Spinal Cord Society. Source


Basoudan N.,University of British Columbia | Basoudan N.,Health Science University | Shadgan B.,International Collaboration on Repair Discoveries | Guenette J.A.,University of British Columbia | And 3 more authors.
European Journal of Applied Physiology | Year: 2016

Purpose: To non-invasively examine the effect of acute hypoxia and inspiratory threshold loading (ITL) on inspiratory muscles [sternocleidomastoid (SCM), scalene (SA) and parasternal (PS)] oxygenation in healthy adults using near-infrared spectroscopy (NIRS). Methods: Twenty healthy adults (12 M/8 F) were randomly assigned to perform two ITL tests while breathing a normoxic or hypoxic (FIO2 = 15 %) gas mixture. NIRS devices were placed over the SCM, PS, SA, and a control muscle, tibialis anterior (TA), to monitor oxygenated (O2Hb), deoxygenated (HHb), total hemoglobin (tHb) and tissue saturation index (TSI). With the nose occluded, subjects breathed normally for 4 min through a mouthpiece that was connected to a weighted threshold loading device. ITL began by adding a 100-g weight to the ITL device. Then, every 2 min 50-g was added until task failure. Vital signs, ECG and ventilatory measures were monitored throughout the protocol. Result: Participants were 31 ± 12 year and had normal spirometry. At task failure, the maximum load and ventilatory parameters did not differ between the hypoxic and normoxic ITL. At hypoxic ITL task failure, SpO2 was significantly lower, and ∆HHb increased more so in SA, SCM and PS than normoxic values. SCM ∆TSI decreased more so during hypoxic compared to normoxic ITL. ∆tHb in the inspiratory muscles (SCM, PS and SA) increased significantly compared to the decrease in TA during both hypoxic and normoxic ITL. Conclusion: The SCM, an accessory inspiratory muscle was the most vulnerable to deoxygenation during incremental loading and this response was accentuated by acute hypoxia. © 2016, Springer-Verlag Berlin Heidelberg. Source


MacGillivray M.K.,University of British Columbia | Manocha R.H.K.,University of Western Ontario | Sawatzky B.,International Collaboration on Repair Discoveries | Sawatzky B.,University of British Columbia
Medical Engineering and Physics | Year: 2016

Forearm crutch technology has evolved slowly compared to other assistive mobility devices, despite the highly repetitive nature of forearm crutch gait and the high incidence of overuse injuries. Using 13 able-bodied volunteers between the ages of 19 and 27, we compared the ground reaction forces of a novel crutch design featuring an elastomeric polymer situated below the handle to an identical design without a damper system and to a commercially available generic rigid forearm crutch model. There were no differences in peak vertical force or impulse between crutches. The crutch with the damper system demonstrated a significantly smaller peak braking force and impulse compared to the generic forearm crutch model. However, the crutch with the damper system demonstrated a significantly larger peak propulsive force and impulse compared to both crutch models. This finding indicates that a forearm crutch with a damper system may help to propel the crutch forward when walking on level surfaces, which could impact forward momentum. © 2016. Source


Zariffa J.,International Collaboration on Repair Discoveries
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference | Year: 2011

Monitoring the activity of specific neural pathways in a peripheral nerve is a task with numerous applications in implanted neuroprosthetic systems. Achieving selective recording using multi-contact nerve cuff electrodes is appealing because these devices are well suited for chronic use, but no viable general solution to the task of discriminating combinations of active pathways from extra-neural recordings has yet been proposed. Bioelectric source localization approaches have been suggested, but their effectiveness is limited by the accuracy of the nerve model used to solve the forward problem. We propose a model-free alternative to the pathway discrimination task, in which experimental data is used to estimate a solution to the forward problem. The method was evaluated using a 56-channel cuff placed on the rat sciatic nerve. 3 pathways were discriminated with a 94.2% success rate when individually active, whereas further improvements are needed in order to recover combinations of simultaneously active pathways. Source


Zariffa J.,International Collaboration on Repair Discoveries | Nagai M.K.,University of Toronto | Schuettler M.,Albert Ludwigs University of Freiburg | Stieglitz T.,Albert Ludwigs University of Freiburg | And 2 more authors.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS | Year: 2011

Monitoring the activity of specific neural pathways in a peripheral nerve is a task with numerous applications in implanted neuroprosthetic systems. Achieving selective recording using multi-contact nerve cuff electrodes is appealing because these devices are well suited for chronic use, but no viable general solution to the task of discriminating combinations of active pathways from extra-neural recordings has yet been proposed. Bioelectric source localization approaches have been suggested, but their effectiveness is limited by the accuracy of the nerve model used to solve the forward problem. We propose a model-free alternative to the pathway discrimination task, in which experimental data is used to estimate a solution to the forward problem. The method was evaluated using a 56-channel cuff placed on the rat sciatic nerve. 3 pathways were discriminated with a 94.2% success rate when individually active, whereas further improvements are needed in order to recover combinations of simultaneously active pathways. © 2011 IEEE. Source

Discover hidden collaborations