Interbalkan Medical Center

Pylaía, Greece

Interbalkan Medical Center

Pylaía, Greece
Time filter
Source Type

Goudis C.A.,General Hospital of Grevena | Korantzopoulos P.,University of Ioannina | Ntalas I.V.,University of Ioannina | Kallergis E.M.,University Hospital of Heraklion | Ketikoglou D.G.,Interbalkan Medical Center
Journal of Cardiology | Year: 2015

Obesity is a worldwide health problem with epidemic proportions that has been associated with atrial fibrillation (AF). Even though the underlying pathophysiological mechanisms have not been completely elucidated, several experimental and clinical studies implicate obesity in the initiation and perpetuation of AF. Of note, hypertension, diabetes mellitus, metabolic syndrome, coronary artery disease, and obstructive sleep apnea, represent clinical correlates between obesity and AF. In addition, ventricular adaptation, diastolic dysfunction, and epicardial adipose tissue appear to be implicated in atrial electrical and structural remodeling, thereby promoting the arrhythmia in obese subjects. The present article provides a concise overview of the association between obesity and AF, and highlights the underlying pathophysiological mechanisms. © 2015.

Goudis C.A.,General Hospital of Grevena | Korantzopoulos P.,University of Ioannina | Ntalas I.V.,University of Ioannina | Kallergis E.M.,University of Crete | And 2 more authors.
International Journal of Cardiology | Year: 2015

Diabetes mellitus (DM) represents one of the most important risk factors for atrial fibrillation (AF) while AF is a strong and independent marker of overallmortality and cardiovascularmorbidity in diabetic patients. Autonomic, electrical, electromechanical, and structural remodeling, including oxidative stress, connexin remodeling and glycemic fluctuations seemto be implicated in AF pathophysiology in the setting of DM. The present reviewhighlights the association between DMand AF, provides a comprehensive overview of the responsible pathophysiological mechanisms and briefly discusses potential upstream therapies for DM-related atrial remodeling. © 2015 Elsevier Ireland Ltd. All rights reserved.

Thanopoulos B.,Iatrikon Medical Center | Giannakoulas G.,University Hospital | Arampatzis C.A.,Interbalkan Medical Center
Catheterization and Cardiovascular Interventions | Year: 2012

Percutaneous pulmonary valve implantation into dysfunctional right ventricular (RV) to pulmonary artery conduits is being increasingly performed in many European and North American centers with satisfactory results and low-complication rates. We report the first application of this elaborate technique in the native RV outflow tract of a young patient who developed severe supravalvular pulmonary stenosis following an arterial switch operation for transposition of the great arteries. The procedure may be used as an alternative to surgical repair for the treatment of selected patients with supravalvular pulmonary stenosis complicating congenital heart surgery. © 2011 Wiley Periodicals, Inc.

Chalidis B.,Interbalkan Medical Center
International journal of immunopathology and pharmacology | Year: 2011

Pulsed electromagnetic fields (PEMF) have been used for several years to supplement bone healing. However, the mode of action of this non-invasive method is still debated and quantification of its effect on fracture healing is widely varied. At cellular and molecular level, PEMF has been advocated to promote the synthesis of extracellular matrix proteins and exert a direct effect on the production of proteins that regulate gene transcription. Electromagnetic fields may also affect several membrane receptors and stimulate osteoblasts to secrete several growth factors such as bone morphogenic proteins 2 and 4 and TGF-beta. They could also accelerate intramedullary angiogenesis and improve the load to failure and stiffness of the bone. Although healing rates have been reported in up to 87 % of delayed unions and non-unions, the efficacy of the method is significantly varied while patient or fracture related variables could not be clearly associated with a successful outcome.

Venouziou A.I.,Interbalkan Medical Center
American journal of orthopedics (Belle Mead, N.J.) | Year: 2013

This retrospective study sought to determine the effectiveness of the acellular human dermal allograft as a bridging device for reconstruction of massive irreparable rotator cuff tears (RCTs). Fourteen patients with an average age of 54.6 years underwent open reconstruction for massive irreparable RCTs. Significant improvement was found for pain and range of motion (ROM). Patient satisfaction was high. The mean American Shoulder and Elbow Surgeons (ASES) score improved from 23.8 points preoperatively to 72.3 postoperatively (P = .001). A significant correlation was found between the size of the tendon gap, which was bridged with the allograft, and the pain, ROM and ASES score. Patients with less than 2 cm tendon gap had a better outcome than those with greater tendon defects. Open reconstruction of chronic massive irreparable RCTs with human dermal allograft interposition is an alternative technique with encouraging short-term results. Our study indicates that the dermal allograft can be used safely to bridge tendon gaps of up to 2 cm with great success.

Assiotis A.,Charring Cross Hospital | Sachinis N.P.,Interbalkan Medical Center | Chalidis B.E.,Interbalkan Medical Center
Journal of Orthopaedic Surgery and Research | Year: 2012

Background: Pulsed electromagnetic fields (PEMF) stimulation for the treatment of bone nonunion or delayed union have been in use for several years, but on a limited basis. The aim of this study was to assess the overall efficacy of the method in tibial delayed unions and nonunions and identify factors that could affect the final outcome.Methods: We prospectively reviewed 44 patients (27 men) with a mean age of 49.6 ± 18.4 years that received PEMF therapy due to tibial shaft delayed union or nonunion. In all cases, fracture gap was less than 1 cm and infection or soft tissue defects were absent.Results: Fracture union was confirmed in 34 cases (77.3%). No relationship was found between union rate and age (p = 0.819), fracture side (left or right) (p = 0.734), fracture type (simple or comminuted, open or closed) (p = 0.111), smoking (p = 0.245), diabetes (p = 0.68) and initial treatment method applied (plates, nail, plaster of paris) (p = 0.395). The time of treatment onset didn't affect the incidence of fracture healing (p = 0.841). Although statistical significance was not demonstrated, longer treatment duration showed a trend of increased probability of union (p = 0.081).Conclusion: PEMF stimulation is an effective non-invasive method for addressing non-infected tibial union abnormalities. Its success is not associated with specific fracture or patient related variables and it couldn't be clearly considered a time-dependent phenomenon. © 2012 Assiotis et al.; Licensee BioMed Central Ltd.

Theodosiadis P.,Interbalkan Medical Center
Journal of orthopaedic surgery (Hong Kong) | Year: 2013

To compare the use of ropivacaine versus bupivacaine for 3-in-1 block during total knee arthroplasty (TKA) in terms of efficacy and safety (lack of toxicity). 14 men and 26 women aged 58 to 77 (median, 70) years who had the American Society of Anesthesiologists (ASA) grades I to III physical status were randomised to receive ropivacaine (n=20) or bupivacaine (n=20) of a concentration of 0.5% for 3-in-1 block during TKA. The dosage was 0.5 ml/kg. In addition, a sciatic nerve block (20 ml of prilocaine 1%) was used. The onset of the block, duration of postoperative analgesia, level of motor block, and any side-effects were compared. The median time to onset of block was significantly shorter in those receiving ropivacaine than bupivacaine (13 vs. 17.5 minutes, p<0.001), but the levels of motor blockade were not significantly different (p=0.355). Complete analgesia was achieved throughout the procedure. There was no significant difference between the ropivacaine and bupivacaine groups in terms of the mean duration of analgesia (398 vs. 367 minutes, p=0.62), the mean VAS scores at all time points, and the mean total morphine consumption. One patient in the ropivacaine group developed a joint haematoma and 2 patients in the bupivacaine group had excessive wound drainage. Both conditions resolved after antibiotic use. Ropivacaine and bupivacaine showed similar anesthetic and analgesic effects, but the former had a significantly faster onset time.

Chourmouzi D.,Interbalkan Medical Center | Papadopoulou E.,Interbalkan Medical Center | Drevelegas A.,Interbalkan Medical Center
Journal of Medical Case Reports | Year: 2010

Introduction. Pseudo-Meigs' syndrome is a rare pathological entity characterized by the presence of a pelvic mass other than an ovarian fibroma. The mass is associated with ascites with or without hydrothorax. Case presentation. We describe the case of a 41-year-old Caucasian woman with a large uterine leiomyoma associated with massive ascites. A magnetic resonance imaging scan showed a large subserosal leiomyoma with multiple areas of cystic degeneration. Conclusion. To the best of our knowledge, this is the first reported case of pseudo-Meigs' syndrome caused by a uterine leiomyoma and diagnosed using magnetic resonance imaging. The pathophysiology of this syndrome and the role of magnetic resonance imaging are emphasized in this case report. © 2010 Chourmouzi et al; licensee BioMed Central Ltd.

Emmanouilides C.,Interbalkan Medical Center
Archives of Hellenic Medicine | Year: 2016

Oncological patients enjoy increasingly longer survival, mainly due to the introduction of innovative but costly therapeutic agents. In addition, the aging of the population in Greece is expected to increase the absolute incidence of cancer. The above two developments will strain the country’s available health resources. The National Health System should adapt to the new challenges rapidly and efficiently. An overhaul of the organization of oncological care providers in Greece is long overdue. In order to realize cost savings, large scale operations must become the norm, with rational allocation of the available funds and efficient single payment facilities, so that affordable coverage remains feasible. Major changes are needed in the anchor oncology hospitals in order for them to play the role of regional leaders in oncological care, including the merging of similar divisions, subspecialization of services, promotion of clinical research and operational continuity of association with oncologists in lesser centers. In addition, joint operations in training and patient care should be pursued with major private centers, overcoming mutual mistrust and obsolete inflexibility. The current financial crisis represents an excellent opportunity for the revision and restructuring of oncological care in Greece, which should take into account societal needs and be based on flexibility and efficiency. © Athens Medical Society.

Emmanouilides C.,Interbalkan Medical Center
Forum of Clinical Oncology | Year: 2015

Cancer is becoming a major public health issue as patients enjoy longer survivals than ever before due to the introduction innovative but expensive drugs in the clinic. In addition, the ageing of the population in Greece is expected to increase the absolute incidence of cancer. The National Health System should rapidly and efficiently adapt to the new challenges, including increased pharmaceutical costs. Resources ought to be allocated rationally and efficiently while maintaining adequate coverage for the insured population. Economising due to large-scale operations should be pursued by the governmental single payor (EOPYY), so that affordable coverage remains feasible. Establishment of mechanisms to deal with new and very costly drugs should be put in place. The major changes in anchor oncologic hospitals are needed in order to play a role as regional leaders in oncologic care, including merging of similar divisions, sub-specialisation of services and promotion of clinical research. These major centres could coordinate a host of satellite oncology services in other urban hospitals and in the provinces. In addition, joint operations in training and patient care should be pursued with major private centres, without mutual mistrust or obsolete inflexibilities. The current financial crisis represents an excellent opportunity for revisioning and restructuring oncologic care in Greece, taking into account the societal needs and based on flexibility and efficiency. © De Gruyter Open.

Loading Interbalkan Medical Center collaborators
Loading Interbalkan Medical Center collaborators