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Vlachaki E.,Aristotle University of Thessaloniki | Chatzinikolaou K.,Intensive Care Medicine Unit | Bekiari E.,Aristotle University of Thessaloniki | Klonizakis F.,Aristotle University of Thessaloniki | And 2 more authors.

We herein report a case of a thalassemic-patient who was on deferasirox chelation therapy and admitted to the emergency department because of fever, diffuse abdominal pain and altered mental status. Despite the appropriate treatment he died two days later due to cardiac arrest. As we failed to recognize any etiology and the patients' relatives denied a post mortem examination due to religious reasons, we cannot provide any additional data. However, we are wondering whether this incident might be related to deferasirox. © The Author(s) 2011. Source

Yaguiyan-Colliard L.,National Veterinary School of Alfort | Daumas C.,Nutrition and Endocrinology Unit | Nguyen P.,Nutrition and Endocrinology Unit | Grandjean D.,National Veterinary School of Alfort | And 3 more authors.
BMC Research Notes

Abstract Background: Equations based on single-frequency bioelectrical impedance analysis at 50 kHz for determination of total body water content (TBW) have been previously validated in healthy non-sedated beagle dogs. We investigated whether these equations are predictive of TBW in various canine breeds by comparing the results of these equations with TBW values evaluated directly by deuterium oxide (D2O) dilution. Methods: Total body water content of 13 healthy adult pet dogs of various breeds was determined directly using D2O dilution and indirectly using previous equations based on values obtained with a portable bioelectric impedance device. Paired Student's t-tests were used to compare TBW obtained by single-frequency bioelectrical impedance analysis and D2O dilution. A p-value of <0.05 was considered statistically significant for all analyses. Results: Significant differences were observed between TBW determined by the reference method and the values obtained with both predictive equations. Conclusions: The proposed equations including single-frequency bioelectrical impedance analysis parameters validated at 50 kHz in healthy adult beagles need to be modified including morphological parameters such as body size and shape in a first approach. As in humans, morphological-specific equations have to be developed and validated. © 2015 Yaguiyan-Colliard et al. Source

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