Agency: Department of Health and Human Services | Branch: National Institutes of Health | Program: SBIR | Phase: Phase II | Award Amount: 727.22K | Year: 2015
DESCRIPTION provided by applicant In this FastTrack Phase I II SBIR application IFOS in collaboration with the Stanford Center for Design Research CDR proposes to develop and validate an actively steered photo actuated small caliber needle for precise imaging assisted percutaneous procedures This innovation specifically addresses the need for precise needle placement in procedures targeting deep tissue where routes of entry are restricted due to anatomical obstructions and the need to avoid vital organs The proposed active steering can compensate for the deflection encountered during needle insertion into soft tissue which becomes increasingly significant as the path to the target lengthens Such deviations from the planned path can result in multiple reinsertions adding to patient discomfort and procedure time and compromising the effectiveness of minimally invasive procedures The active steering concept is based on optical activation of a shape memory alloy SMA embedded within a flexible stylet Design features compatible with standard needle tips and outer cannula sheaths will be employed Unlike other techniques based on electrical or magnetic actuation the proposed approach is compatible with all major imaging techniques including MRI By using fiber optic connections the stand off distance from the laser power source to the needle can be greater than that for actuation motors required for tendon approaches The technique requires minimal power input and can be implemented in a user friendly hand held biopsy needle system While the basic needle concept does not rely on complex algorithms and robotic needle insertion systems the basic design includes a streamlined back end that affords a ready connection to more complex instrumentation including advanced online imaging interface capabilities In prior work bending rates of over per second have been repeatably achieved in phantoms that mimic the properties of human prostate tissue Also the collateral temperature rise in surrounding tissue was shown to be minimal effectively eliminating thermal damage as a concern The Phase I effort is designed to demonstrate still greater deflection efficiency using various needle insertion strategies in ex vivo prostate tissue using a novel approach involving low transition temperature SMAs and optimized superelastic biopsy needle structures and control This work will lead to further development activities in Phase II including thinner needl designs a console design and a closed loop control system that enables real time needle curvature and in situ tissue reaction force measurements In Phase II we also will investigate steering protocols that would take advantage of axial rotation and other known passive control strategies thereby adding bending degrees of freedom and dexterity to the needle system These studies will culminate in a series of in vivo experiments targeting prostate biopsy and brachytherapy procedures under imaging modalities such as ultrasound and MRI to establish key clinical efficacy and safety parameters and validate practical clinical aspects for facilitatig FDA approval and the successful introduction of the new active needle to end users PUBLIC HEALTH RELEVANCE This research will develop technology for the active steering of needles under imaging assisted percutaneous procedures including biopsy and surgical interventions A controllable small gage biopsy needle would enhance the targeting precision and overall efficacy of minimally invasive deep tissue surgical procedures while enhancing safety and patient comfort The active device will comprise an easy to operate versatile and MRI compatible class of small gauge needles that will improve procedure success rates reduce bleeding complications due to multiple insertions significantly shorten procedure times and could bring many new procedures to the MRI suite while advancing the field of smart needle development for robotic surgery tools with broad based spin off applications for both oncological and non oncological medical fields
Agency: Department of Transportation | Branch: | Program: SBIR | Phase: Phase I | Award Amount: 150.00K | Year: 2015
IFOS will develop a hybrid fiber optic sensing system focused on transit rail systems. It will combine (1) Brillouin Optical Time Domain Analysis provide a larger reach for strain and temperature measurement, and (2) broadband FBG sensing technology to provide calibration and extra sensing capabilities in hotspots as well as verify the strain and temperature discrimination in the Brillouin measurement. The broadband nature will enable measurement of low frequency strains and forces as indicators of track buckling and the high frequency measurements will enable acoustic emission detection as a damage indicator. In addition the system will include signal processing software to extract the component of track rail vibrations indicating precise speed and loading as well as have the potential to save lives by providing indicators of trespassing or obstructions on the track.
Agency: Department of Defense | Branch: Navy | Program: SBIR | Phase: Phase I | Award Amount: 84.99K | Year: 2015
IFOS will design, develop, and mature fiber optic based ultra-high temperature (UHT) sensor technology for blade tip clearance and vibration measurements. In Phase-I, IFOS will identify the fiber optic UHT sensor technology details including fiber sensor material, sensor mounting, sensor tip coating, and methods of integration with turbin
Agency: Department of Health and Human Services | Branch: | Program: SBIR | Phase: Phase I | Award Amount: 218.08K | Year: 2014
DESCRIPTION (provided by applicant): In this FastTrack Phase I/II SBIR application, IFOS, in collaboration with the Stanford Center for Design Research (CDR) proposes to develop and validate an actively steered, photo-actuated, small-caliber needle for precise imaging-assisted percutaneous procedures. This innovation specifically addresses the need for precise needle placement in procedures targeting deep tissue, where routes of entry are restricted due to anatomical obstructions and the need to avoid vitalorgans. The proposed active steering can compensate for the deflection encountered during needle insertion into soft tissue, which becomes increasingly significant as the path to the target lengthens. Such deviations from the planned path can result in multiple reinsertions, adding to patient discomfort and procedure time, and compromising the effectiveness of minimally invasive procedures. The active steering concept is based on optical activation of a shape memory alloy (SMA) embedded within a flexi
Agency: Department of Defense | Branch: Defense Advanced Research Projects Agency | Program: SBIR | Phase: Phase II | Award Amount: 1.51M | Year: 2015
Intelligent Fiber Optic Systems Corporation (IFOS) and Stanford University (SU) intend to demonstrate a 150 meter long, 12-sensor depth insensitive pressure sensor array. The overall goal of this SBIR project is to develop an innovative, passive, low-power array of acoustic pressure and vector sensors that can operate effectively across all ocean depths to detect, classify, and localize low-level signals. The focus is on optical sensor technology, low-power array sensor optical telemetry, and the interrogator/demodulator. The proposed technology will have application to submarine detection in deep (> 6 kilometer) deployments and will be miniaturized for implementation in A-size sonobuoys.