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Bolesta D.,Kolo Naukowe Dentico przy Zakladzie Stomatologii zieciqcej. | Hoscilowicz P.D.,Kolo Naukowe Dentico przy Zakladzie Stomatologii zieciqcej. | Knas M.,Instytut Ochrony Zdrowia | Waszkiel D.,Zaklad Stomatologii Zachowawczej Uniwersytetu Medycznego w Bialymstoku. | Zalewska A.,Zaklad Stomatologii Zachowawczej Uniwersytetu Medycznego w Bialymstoku.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego | Year: 2013

The uncontrolled accumulation of glucose and fatty acids in the human body without the possibility of any cells utilizing them as metabolic substrates is a typical occurrence in the process of diabetes mellitus. High concentration of mentioned substances leads to oxidative stress and that reasons in numerous complications as a result of diabetes which are often demonstrated in the oral cavity as periodontal inflammations. There are many ways to study the biomarkers of oxidative stress such as: superoxide dismutase (SOD), catalase, glutathione peroxidase, glutathione reductase, glutathione, vitamins, lipid peroxidation, concentration of nitrites, non-enzymatic glycosylation of proteins and hyperglycaemia in diabetes. Considering the attainability and simplicity required to collect, saliva is a popular research material used to test these biomarkers. Source


Knas M.,Instytut Ochrony Zdrowia | Zalewska A.,Medical University of Bialystok | Daniszewska I.,Specjalistyczna Praktyka Stomatologiczna Irena Daniszewska | Waszkiel D.,Medical University of Bialystok
Dental and Medical Problems | Year: 2014

Background. Systemic sclerosis (Sc) is a generalized disease of connective tissue. The most common occupied tissues and organs are, among others, the nervous system and exocrine glands, including the salivary glands. An important group of enzymes involved in the salivary distribution of glycoconjugates are lysosomal exoglycosidases including: N-acetyl-β-D-hexosaminidase, its isoenzymes A and B and β-glucuronidase. Removal of the oligosaccharide chains may lead to the uncovering of the binding epitopes of pathogenic bacteria and to the development of diseases of the oral mucosa or to the increase in the intensity of caries. Objectives. To evaluate of selected saliva lysosomal enzymes N-acetyl-β-D-glucosaminidase, its isoenzymes A and B and β-glucuronidase in the saliva of patients with systemic sclerosis. Material and Methods. The study involved 40 patients with systemic sclerosis meeting the criteria for the American Rheumatism Association and LeRoy. The research material was total saliva, unstimulated and stimulated, taken from the patient by spitting method, before the dental examination. The specific activity of N-acetyl-β-D-hexosaminidase (HEX), its isoenzymes A (HEX A) and B (HEX B) and β-glucuronidase (GLU) was performed according to the Marciniak and Zalewska method. All salivary proteins in resting and stimulated saliva were determined by cynchonic method. Results. The secretion of unstimulated saliva was significantly lower in the group of patients with systemic sclerosis compared to the reference group. A significant decrease in the buffer capacity of unstimulated and stimulated saliva of patients with Sc compared to the reference group was observed. Specific activity of HEX, HEX A, HEX B and GLU were significantly higher in unstimulated saliva of patients with Sc compared to the reference. GLU specific activity in the unstimulated saliva of patients with Sc was significantly higher compared to the reference group. The minute secretion of proteins in the rest saliva of Sc patients was significantly lower compared to the reference group of healthy women. A weak negative correlation between the specific activity of HEX B and minute secretion of unstimulated saliva has been shown. Conclusions. The significant increase of specific activity of all these lysosomal exoglycosidases in unstimulated saliva of Sc patients may contribute to the reduction of the volume of saliva flow and total protein. The significant increase of GLU specific activity in the stimulated saliva of Sc patients can be used as an early indicator of clinically asymptomatic damage of parotid gland during the course of Sc. © Wroclaw Medical University and Polish Dental Society. Source


Lewandowska A.,Instytut Ochrony Zdrowia | Smigielska W.,Instytut Ochrony Zdrowia
Onkologia Polska | Year: 2011

Introduction: Suffering is considered to be a state of an individual caused by physical or mental pain connected with certain disfunction of the organism. Human suffering and the threat of dying is not only the problem of those who suffer but their relatives and medical staff as well. For many people the last moments of life can be connected with unbearable pain that can lead to a crisis or irritation therefore a sick person, a person in pain needs the feeling of security and spiritual support both from their relatives and medical staff. Aim of the study: The aim of the study was the assessment of nurse's role in a suffering patient's care. Material and methods: A hundred of nurses took part in the research. They work in wards of palliative care in Podkarpacie. The research material were data from the questionnaire. Results: Most of the tested nurses (80%) claim that they possess enough job preparation in working with a suffering and dying patient, but only 41% of them completed extra courses or a specialization. Ninety four percent of people from a palliative care ward are satisfied with the job. According to 88% of the nurses from a tested group the ward gives a suffering and dying patient a good care. All the nurses give the patient a needed support, 81% of the tested ones think that they give the family some support after the patient's death. Conclusions: Most of the nurses from the tested group claim that a suffering or dying patient has got a good complex care in a hospital. All tested ones treat a suffering and dying patient in an individual way, with dignity, understanding, sensitivity and compassion. Most of them (91%) claim that they can create a good emotional atmosphere during the patient's last days of life. Copyright © 2011 Cornetis. Source


Lewandowska A.,Instytut Ochrony Zdrowia | Laufer J.,Instytut Ochrony Zdrowia
Onkologia Polska | Year: 2011

Introduction: The problem of neoplastic disease reaches the epidemic level in the world. According tot he data published by Polish Union of Oncology in the year 2000 there were 10 million people who got cancer and 6 million people who died of it. The forecast indicates that 20 million people will get malignant neoplast and half of them will die. Breast cancer is the most common malignant neoplast among women and at the same time the most common reason of death. Every year breast cancer is diagnosed at 1.5 million women and 400 thousand die of it. In breast cancer treatment prophylaxis is the basic issue and the chance to contact medical staff in the form of individual consultation or educational projects organized for big groups of interest. The aim of study: The aim of the study was to analyse healthy behaviours and evaluation of knowledge level of women on the breast cancer subject. Material and methods: 100 women aged 30-40 (38%), 40-50 (40%), 50-60 (22%) living both in urban areas (40%) and rural ones (60%) of podkarpackie voivodship selected at random were included in the study. The method was a survey form. Results: More than a half of them (52%) visit their gynecologists regularly, respondents whereas majority of them (72%) never had a mammography done and breast ultrasonography was never done at more than a half of women (52%). Majority of women (64%) do not do breast self-examination. Conclusion: Only 22% of women do a regular breast self-examination, the most popular technique 36% is the circular movement whereas 46% women do not know any. Copyright © 2011 Cornetis. Source


Lewandowska A.,Instytut Ochrony Zdrowia | Mess E.,Katedra Pielegniarstwa Klinicznego | Kruk W.,Instytut Ochrony Zdrowia
Onkologia Polska | Year: 2012

Introduction: In many areas of the world, including the European Union, women organs' cancer is on the increase. It is particularly disturbing as younger and younger women get malignant neoplast. Thorough knowledge on breast and women's organs cancer and regular check-ups and prophylaxis are the most important factors diminishing the risk of cancer. The aim of study: The aim of the study was to evaluate women's knowledge on uterine cervix cancer and breast cancer prophylaxis. Material and methods: The study included a hundred women aged 20-59 living in podkarpackie voivodship selected at random. Results: More than a half of women included in the study (58%) get their knowledge on prophylaxis from the Internet, television and radio, 18% from their doctors or nurses and 16% from medical literature and the remaining 8% from other sources. The forms of prophylaxis according to the women in question are: diet rich in vegetables and fruit (56%), breast feeding (36%), proper weight (30%), physical activity (24%). The most often indicated signs of cancer are: tumour in the breast or in the armpit (96%), bloody secretion from the nipple, bloody vaginal discharge (62%), incorrect menstrual bleeding (50%), pains in pubic regions (34%). Conclusions: The most often indicated factor influencing uterine cervix cancer development is human pappiloma virus HVP (52%) and genetic load in case of breast cancer (64%). Women included in the survey who know the symptoms of neoplast disease name watery vaginal discharge with blood (62%) - uterine cervix cancer and tumour in the breast or in the armpit (96%). Copyright © 2012 Cornetis. Source

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