Preparation of polylactide scaflolds with squashy structure for cell culture-a preliminary research and optimization [Otrzymywanie polilaktydowych rusztowan komórkowych o strukturze gabczastej-badania wstepne i optymalizacja procesu]
Kruk A.,Warsaw University of Technology |
Gadomska-Gajadhur A.,Warsaw University of Technology |
Ruskowski P.,Warsaw University of Technology |
Chwojnowski A.,Instytut Biocybernetyki i Inzynierii Biomedycznej Im. Macieja Nalecza PAN |
Synoradzki L.,Warsaw University of Technology
Polimery/Polymers | Year: 2017
A study on the preparation of polylactide scaffolds for columnar epithelium cells (size ∼ 60 μm) were presented. Preliminary studies and optimization of the process were carried out. The regression equation describing the inffuence of pore precursor/polylactide weight ratio, concentration of polylactide in 1,4-dioxane and volume ratio of MeOH/H2O in the coagulation bath on the diameter of the pores has been established. The optimal conditions which yield the biggest pores in the range 50-100 μm in the cross-section were designed.