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Zalewska E.,Instytut Biocybernetyki i Inzynierii Biomedycznej im
Family Medicine and Primary Care Review | Year: 2015

The article is a summary of the study on the issue of atypical motor unit potentials, which according to standard criteria are usually eliminated from the analysis. They have, in fact, irregular shapes and make the difficulty in an automatic analysis. Atypical potentials are recorded in both myopathic and neurogenic processes and are usually eliminated from the automatic analysis as outliers. The most interesting group of atypical motor unit potentials, and also the hardest to interpret, represent potentials with complex shapes, such as long polyphasic potentials recorded in myopathies or irregular potentials with high amplitude recorded in Emery-Dreifuss dystrophy. Motor unit potentials with satellite components are a specific type of atypical potentials. Results of the study reveal possible diagnostic yield of atypical potentials. Such potentials may be of diagnostic importance and evaluation of their irregularities may be an indicator of the intensity of the pathological process. Modelling of motor unit potentials was used to explain the origin of irregular motor unit potentials, understanding and explanation of a series of clinical observations that were not to explain on the basis of clinical, or even experimental trials. Modelling enabled the determination of morphological conditions necessary to formation of potential of irregular shape. Inverse modelling, which is the approximation of the structure of the motor unit on the basis of an analysis of its potential can extend the scope of the diagnostic utility of electromyography, motor unit activities interpretation of its morphology. © by Wydawnictwo Continuo. Source


Wladyslaw T.,Instytut Biocybernetyki i Inzynierii Biomedycznej im | Pijanowska D.G.,Instytut Biocybernetyki i Inzynierii Biomedycznej im
Przeglad Elektrotechniczny | Year: 2012

In this paper, basic considerations concerning graphene structure and review of its properties, methods of manufacturing and applications - mainly in electronics and measurements are presented. Promising results are expected for this material because of its competitive electronic, optical, optoelectronic, electrochemical and mechanical properties in comparison to silicon that is commonly utilized for construction of different sensors, sensors array and measuring microsystems. Examples of graphene applications in measuring techniques are discussed. Source


Kazimierczak B.,Instytut Biocybernetyki i Inzynierii Biomedycznej im | Baraniecka A.,Instytut Biocybernetyki i Inzynierii Biomedycznej im | Baraniecka A.,Polish Institute of Electron Technology | Pijanowska D.,Instytut Biocybernetyki i Inzynierii Biomedycznej im
Przeglad Elektrotechniczny | Year: 2010

C-reactive protein (CRP) is acute phase serum protein and serves as a very sensitive, nonspecific marker and predictor of cardiovascular events. The amperometric immunosensor for human CRP is based on a direct ELISA test with anti-CRP antibodies labeled with alkaline phosphatase and ascorbic acid phosphate as an substrate for the enzyme. Voltamperometric measurements were performed with screen-printed 3-electrode amperometric sensors, where counter and working electrodes were made of carbon pastes, and a reference electrode was electrochemically chlorinated silver/silver chloride one. The obtained sensor sensitivity calculated for the CRP concentration range up 12 mg/L (cut-off value for men used in Polish analytical laboratories) was 0,57 μA/mg/L and linear correlation coefficient of 0,998. Source


Jankowska-Sliwinska J.,Instytut Biocybernetyki i Inzynierii Biomedycznej im | Kruk J.,Instytut Biocybernetyki i Inzynierii Biomedycznej im | Pijanowska D.G.,Instytut Biocybernetyki i Inzynierii Biomedycznej im | Torbicz W.,Instytut Biocybernetyki i Inzynierii Biomedycznej im
Przeglad Elektrotechniczny | Year: 2010

Biosensors are a kind of analytical tool that combine recognition biomolecules with a transducer, which transforms (bio)chemical information into a chemical or physical signal. Direct electrochemical detection of DNA consists in analysis of oxidation current peaks of nitrogenous bases: adenine, guanine, tymine and cytosine. In the experiments, sensors with working electrodes made of gold, platinum and carbon were used. All experiments were carried out with short, single stranded DNA - oligonucleotides, without modified ends. In the case of carbon and gold sensors the resulting current was correlated with oligonucleotides concentration in the testing solution, but in the case of platinum sensor, any correlation was observed. Further experiments will be oriented towards elaboration of immobilization method. Source

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