Instrument Technology Research Center

Hsinchu Taiwan, Taiwan

Instrument Technology Research Center

Hsinchu Taiwan, Taiwan
Time filter
Source Type

Sugiyama T.,Instrument Technology Research Center | Yuyama K.-I.,National Chiao Tung University | Masuhara H.,National Chiao Tung University
Accounts of Chemical Research | Year: 2012

Laser trapping has served as a useful tool in physics and biology, but, before our work, chemists had not paid much attention to this technique because molecules are too small to be trapped in solution at room temperature. In late 1980s, we demonstrated laser trapping of micrometer-sized particles, developed various methodologies for their manipulation, ablation, and patterning in solution, and elucidated their dynamics and mechanism. In the 1990s, we started laser trapping studies on polymers, micelles, dendrimers, and gold, as well as polymer nanoparticles. Many groups also reported laser trapping studies of nanoclusters, DNA, colloidal suspensions, etc. Following these research streams, we have explored new molecular phenomena induced by laser trapping. Gradient force leading to trapping, mass transfer by local heating, and molecular reorientation following laser polarization are intimately coupled with molecular cluster and aggregate formation due to their intermolecular interactions, which depend on whether the trapping position is at the interface/surface or in solution.In this Account, we summarize our systematic studies on laser trapping chemistry and present some new advances and our future perspectives. We describe the laser trapping of nanoparticles, polymers, and amino acid clusters in solution by focusing a continuous wave 1064 nm laser beam on the molecules of interest and consider their dynamics and mechanism. In dilute solution, nanoparticles with weak mutual interactions are individually trapped at the focal point, while laser trapping of nanoparticles in concentrated solution assembles and confines numerous particles at the focal spot. The assembly of polymers during their laser trapping extends out from the focal point because of the interpolymer interactions, heat transfer, and solvent flow. When the trapping laser is focused at an interface between a thin heavy water solution film of glycine and a glass substrate, the assembled molecules nucleate and evolve to a liquid-liquid phase separation, or they will crystallize if the trapping laser is focused on the solution surface. Laser trapping can induce spatiotemporally the liquid and solid nucleation of glycine, and the dense liquid droplet or crystal formed can grow to a bulk scale. We can control the polymorph of the formed glycine crystal selectively by tuning trapping laser polarization and power. These results provide a new approach to elucidate dynamics and mechanism of crystallization and are the fundamental basis for studying not only enantioselective crystallization but also confined polymerization, trapping dynamics by ultrashort laser pulses, and resonance effect in laser trapping. © 2012 American Chemical Society.

Yuyama K.-I.,National Chiao Tung University | Sugiyama T.,Instrument Technology Research Center | Masuhara H.,National Chiao Tung University
Journal of Physical Chemistry Letters | Year: 2013

We present laser trapping behavior of l-phenylalanine (l-Phe) at a surface of its unsaturated aqueous solution by a focused continuous-wave (CW) near-infrared (NIR) laser beam. Upon the irradiation into the solution surface, laser trapping of the liquid-like clusters is induced concurrently with local laser heating, forming an anhydrous plate-like crystal at the focal spot. The following laser irradiation into a central part of the plate-like crystal leads to laser trapping at the crystal surface not only for l-Phe molecules/clusters but also for polystyrene (PS) particles. The particles are closely packed at crystal edges despite that the crystal surface is not illuminated by the laser directly. The molecules/clusters are also gathered and adsorbed to the crystal surface, leading to crystal growth. The trapping dynamics and mechanism are discussed in view of optical potential formed at the crystal surface by light propagation inside the crystal. © 2013 American Chemical Society.

Hsu M.-Y.,Instrument Technology Research Center | Chang S.-T.,Instrument Technology Research Center | Huang T.-M.,Instrument Technology Research Center
Terrestrial, Atmospheric and Oceanic Sciences | Year: 2017

During the Acquisition and Safe Hold (ASH) mode, FORMOAT-5 (FS5) satellite attitude is not fully controlled. Direct sun exposure on the Remote Sensing Instrument (RSI) satellite telescope sensor may occur. The sun exposure effect on RSI sensor performance is investigated to evaluate the instrument's survivability in orbit. Both satellite spin speed and sun exposure duration are considered as the key parameters in this study. A simple radiometry technique is used to calculate the total sun radiance exposure to examine the RSI sensor integrity. Total sun irradiance on the sensor is computed by considering the spectral variation effect through the RSI's five-band filter. Experiments that directly expose the sensor to the sun on the ground were performed with no obvious performance degradation found. Based on both the analysis and experiment results, it is concluded that the FS5 RSI sensor can survive direct sun exposure during the ASH mode.

Tang Y.-W.,Instrument Technology Research Center
I2MTC 2017 - 2017 IEEE International Instrumentation and Measurement Technology Conference, Proceedings | Year: 2017

While biomedical optical sensing technology is getting mature, it quickly and widely penetrates into wearable devices, medical devices, or brain energy analyzers. Its noninvasive measurement makes it rapidly growth today, and near infrared spectroscopy (NIRS) is a typical case. In previous researches, a self-developed EEG-NIRS system is succeeded in monitoring the brain activity changes. This system provides local region blood oxygen concentration changes and more physical information. The results reveal that the determination results are susceptible to the sensor position deviation that is caused by the unstable measurement results. Therefore, a concept of invasive reflection type near infrared imaging (NIRI) sensor module was proposed to solve this problem. New brain monitoring system is composed of an image sensor, dual wavelength light source and a central control unit. By a continuous cooperation of light source and imager, local region blood oxygen concentration changes are calculated and updated with a 2.5 frames per second speed. Besides that, an ambient light subtraction technique is also adopted to eliminate the noise. © 2017 IEEE.

Tsai C.-L.,Chang Jung Christian University | Chang H.-C.,Instrument Technology Research Center
Kybernetes | Year: 2016

Purpose – The purpose of this paper is to collate relevant literature on the theoretical background of regional innovation systems and factors that impact the operational effectiveness of regional innovation systems. Design/methodology/approach – The collated information is then used to determine the opinions of experts from industries within science-based parks, and the scholars on the researches of regional innovation systems in Taiwan. The analytic hierarchy process (AHP) is used to evaluate the critical factors of regional innovation systems. Findings – This study finds that industry cluster effects constitute the most significant operating factor for regional innovation systems within the Taiwanese science-based parks. In addition, this study not only confirms that partners or parent firm location which were advocated by Tödtling et al. are also critical to Taiwanese regional innovation systems, but also verifies how well the relationships to partners or parent firm are equally important for expansion the regional innovation systems. Research limitations/implications – The concepts of regional innovation system have been established since 1990, and related articles have been published from European and Asian scholars, however, seldom does literature offer questionnaires or research items to measure the operational effectiveness of a regional innovation system. Therefore this study has developed a questionnaire, by reviewing literature and verifying it by the AHP method, with Taiwan’s HsinChu Science Park as the subject case. For the contribution on theories, this study inducted the construction of new innovation environments, new interactional behavior in regional organization innovation, and injection of new resources into regional innovation as the three main constructs to influence the operational effectiveness of regional innovation systems. In addition, this study has used experts’ questionnaire answers and the AHP method to clarify the priority of factors to operate the regional innovation system. Practical implications – Industry cluster effect, construction of knowledge infrastructure and how close partners or parent firm are (distance and relationship) are the top three factors in HsinChu Science Park. The duties of the government are not merely picking good firms for the regional innovation system, but also making policies and defining regimes, providing a good business environment for campus firms, universities, and research institutions, as well as offering plenty of R&D funding to encourage industry-academia cooperation. Governments must invest in infrastructures, such as: establishing databases, libraries, information networks, the national technical standards for certification, and other public services, to facilitate industry-academia cooperation. Social implications – These research results indicate the operating essentials of regional innovation systems are not limited to interactions among regional organizations. This study suggests that the success or failure of a new regional innovation system would instead, be dependent on the regional environment, as in software planning and support, as well as the relationship of innovation with policy implementation and administration. Originality/value – Results showed that the top-five factors influencing the operational effectiveness of regional innovation systems are the industry cluster effect, the construction of knowledge infrastructure, how close to partner’s or parent’s firm (distance and relationship), import of foreign capital and technology, and the implementation of regional innovation policy. © 2016, © Emerald Group Publishing Limited.

Lin Y.-S.,National Tsing Hua University | Yeh J.A.,National Tsing Hua University | Yeh J.A.,Instrument Technology Research Center
Applied Physics Express | Year: 2011

High-efficiency GaN-based light-emitting diodes (LEDs) with an emitting wavelength of 438nm were demonstrated utilizing nanoscale patterned sapphire substrates with void-embedded cortex-like nanostructures (NPSS-VECN). Unlike the previous nanopatterned sapphire substrates, the presented substrate has a new morphology that can not only improve the crystalline quality of GaN epilayers but also generate a void-embedded nanostructural layer to enhance light extraction. Under a driving current of 20 mA, the external quantum efficiency of an LED with NPSS-VECN is enhanced by 2.4-fold compared with that of the conventional LED. Moreover, the output powers of two devices respectively are 33.1 and 13.9 mW. © 2011 The Japan Society of Applied Physics.

Yang C.-C.,Instrument Technology Research Center | Tsai H.-Y.,Instrument Technology Research Center | Huang K.-C.,Instrument Technology Research Center
Optical Review | Year: 2013

White LEDs (WLEDs) have various yellow-ring (YR) effects when projected onto differing backgrounds. These effects are determined by the material that the WLED is projected onto. In our previous study, the YR phenomenon was expressed as the yellow-ring index (YRI), which comprises yellow light intensity (Y) and light intensity (I), and the maximum value of the YRI curve is a crucial optical parameter for determining the degree of the YR phenomenon. This study presents a modified evaluation model using YR degree and four YR diagrams (the YRIs are less than 5, 5 to 10, 10 to 15, and greater than 15) as the criterion for WLED quality control. © 2013 The Optical Society of Japan.

Liao B.-H.,Instrument Technology Research Center | Hsiao C.-N.,Instrument Technology Research Center
Applied Optics | Year: 2014

Silicon nitride films are prepared by a combined high-power impulse/unbalanced magnetron sputtering (HIPIMS/UBMS) deposition technique. Different unbalance coefficients and pulse on/off ratios are applied to improve the optical properties of the silicon nitride films. The refractive indices of the Si3N4films vary from 2.17 to 2.02 in the wavelength ranges of 400-700 nm, and all the extinction coefficients are smaller than 1 × 10-4. The Fourier transform infrared spectroscopy and x-ray diffractometry measurements reveal the amorphous structure of the Si3N4films with extremely low hydrogen content and very low absorption between the near IR and middle IR ranges. Compared to other deposition techniques, Si3N4films deposited by the combined HIPIMS/UBMS deposition technique possess the highest refractive index, the lowest extinction coefficient, and excellent structural properties. Finally a four-layer coating is deposited on both sides of a silicon substrate. The average transmittance from 3200 to 4800 nm is 99.0%, and the highest transmittance is 99.97% around 4200 nm. © 2014 Optical Society of America.

Instrument Technology Research Center | Date: 2013-05-28

A method for preparing a hemisphere-shaped dosage form containing drug. A high molecular weight solution containing the drug is prepared, and the solution is then dropped onto a base material. The interface phenomenon between the solution and different base materials causes the solution to form a hemisphere-shaped liquid drop dosage. After solidifying by cross-link or evaporation, a hemisphere-shaped dosage form containing drug is obtained. The advantages of the preparation method are a simple and fast process, and simple operation. Applications of the preparation method to prepare a hemisphere-shaped dosage form containing drug are also provide.

Instrument Technology Research Center | Date: 2011-04-07

A novel TCO coating and its manufacturing method are disclosed. The TCO coating of the present invention consists of titanium oxide, silicon oxide and metal. The TCO coating is manufactured according to electromagnetic field simulation software basing on the Maxwell Equations. Because the manufacturing method (including steam plating and sputter plating) of the present invention may be carried out under the room temperature, base boards that are made of polymer and that can not withstand high temperatures may be used and hence base boards may have wider applications. Also, less time is needed in the production, production cost is lowered and mass-production may be achieved.

Loading Instrument Technology Research Center collaborators
Loading Instrument Technology Research Center collaborators