Instituto Portugues Of Oncologia Of Lisbon Of Francisco Gentil Epe

Lisbon, Portugal

Instituto Portugues Of Oncologia Of Lisbon Of Francisco Gentil Epe

Lisbon, Portugal
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Limbert E.,Instituto Portugues Of Oncologia Of Lisbon Of Francisco Gentil | Prazeres S.,Instituto Portugues Of Oncologia Of Lisbon Of Francisco Gentil | Sao Pedro M.,Instituto Portugues Of Oncologia Of Lisbon Of Francisco Gentil | Madureira D.,Instituto Portugues Of Oncologia Of Lisbon Of Francisco Gentil | And 10 more authors.
Acta Medica Portuguesa | Year: 2012

Objective: The aim of the present study was to evaluate iodine intake in portuguese school children in order to inform health authorities of eventual measures to be implemented. Introduction: Iodine is the key element for thyroid hormone synthesis and its deficiency even mild, as found in other European countries, may have deleterious effects in pregnancy resulting in cognitive problems of offsprings. In Portugal there are no recent data on iodine intake in schoolchildren. Population and methods: 3680 children aged 6-12 years of both sexes, from 78 different schools were studied. Iodine intake was evaluated trough urine iodine (UI) determinations using a colorimetic method. Results: The global median UI value was 105.5 μg/L; the percentage of children with UI <100 μg/L was 47.1%, corresponding to 41% of the studied schools. The percentage of values <50 μg/L was 11.8%. The male gender, the south region of the country and the distribution of milk in school were significantly linked with a higher iodine elimination. Discussion: Our global results point to a borderline/ mildly insufficient iodine intake in the portuguese school population. However 47% of the children had UI under 100 μg /L. The comparison of our results with the available data from 30 years ago, point to a considerable improvement, due to silent prophylaxis. Male gender, geographical area and milk distribution influenced positively iodine intake.The importance of milk has been refered in numerous papers. Conclusions: The study of UI in the Portuguese school population points to a borderline iodine intake. However, in 47% of children iodine intake was inadequate. Compared with data from the eighties, a considerable increase in iodine elimination was found. Taking into account the potencial deleterious effects of inadequate iodine intake, a global prophylaxis with salt iodization has to be considered. © Ordem dos Médicos 2012.


Papoila A.L.,New University of Lisbon | Papoila A.L.,University of Lisbon | Riebler A.,Norwegian University of Science and Technology | Amaral-Turkman A.,University of Lisbon | And 7 more authors.
Biometrical Journal | Year: 2014

Stomach cancer belongs to the most common malignant tumors in Portugal. Main causal factors are age, dietary habits, smoking, and Helicobacter pylori infections. As these factors do not only operate on different time dimensions, such as age, period, or birth cohort, but may also vary along space, it is of utmost interest to model temporal and spatial trends jointly. In this paper, we analyze incidence of stomach cancer in Southern Portugal between 1998 and 2006 for females and males jointly using a spatial multivariate age-period-cohort model. Thus, we avoid age aggregation and allow the exploration of heterogeneous time trends between males and females across age, period, birth cohort, and space. Model estimation is performed within a Bayesian setting assuming (gender specific) smoothing priors. Our results show that the posterior expected rate of stomach cancer is decreasing for all counties in Southern Portugal and that males around 70 have a two times higher risk of getting stomach cancer compared with their female counterparts. We further found that, except for some few counties, the spatial influence is almost constant over time and negligible in the southern counties of Southern Portugal. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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