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Tellez-Castillo C.J.,Laboratorio Of Microbiologia Clinica Y Servicio Of Urgencias | Granda D.G.,Laboratorio Of Microbiologia Clinica Y Servicio Of Urgencias | Alepuz M.B.,Laboratorio Of Microbiologia Clinica Y Servicio Of Urgencias | Lobo V.J.,Institute Recursos Naturales y Agrobiologia | And 3 more authors.
Journal of Medical Microbiology | Year: 2010

Here we report two cases of isolation of Aurantimonas altamirensis from pleural fluid and blood. The strains were identified by 16S rRNA gene sequencing. A. altamirensis appears to be a rare pathogen involved in unusual infectious processes, and must be isolated and studied at the molecular level for correct clinical diagnosis. © 2010 SGM.

Rodriguez de la Pinta M.L.,Hospital Universitario Puerta Of Hierro | Castro Lareo M.I.,Complejo Hospitalario Universitario | Ramon Torrell J.M.,IDIBELL | Garcia de Lomas J.,Instituto Valenciano Of Microbiologia | And 5 more authors.
Vaccine | Year: 2016

Introduction: This multi-center, hospital-based observational study determined the seroprevalence of pertussis antibodies amongst healthcare professionals from three different hospitals in Spain to ascertain the health status of professionals attending to susceptible groups who are at risk of contracting and transmitting pertussis. Methods: Medical professionals from three hospitals in Spain were recruited for this study (NCT01706224). Serum samples from subjects were assessed for anti-pertussis antibodies by ELISA. The percentage of subjects positive for anti-pertussis antibodies were determined by age-strata, gender, vaccination status, professional level (physicians, nurses, ancillary nurses and midwives), hospital department, number of working years, numbers of hours spent with the patient as well as number of children in the household. Results: Overall, 31.2% of subjects were seropositive; 3.3% of these healthcare professionals had ELISA values indicative of current or recent infection. There were no significant differences in terms of pertussis prevalence with respect to age, gender, hospital department, profession, number of working years and number of hours spent with patients. These levels of seronegativity amongst healthcare workers further strengthen the rationale for vaccination amongst this specific population against pertussis. © 2016.

Machado I.,Instituto Valenciano Of Oncologia | Garcia Lozano T.,Instituto Valenciano Of Oncologia | Juan Banon J.L.,Instituto Valenciano Of Microbiologia | Cruz Mojarrieta J.,Instituto Valenciano Of Oncologia | Estevan R.,Instituto Valenciano Of Oncologia
Revista Espanola de Patologia | Year: 2012

Introduction: Intra-abdominal granulomatosis caused by fungal infection is infrequent and difficult to diagnose. The histopathology usually reveals a chronic inflammatory reaction with multinucleated giant cells, yeast, hyphae and/or conidia. Material and methods: We report a case of a 51-year-old woman with a previous history of endometrial adenocarcinoma and repeated abdominal surgery associated with intrabdominal infection, which was treated with various antibiotics and antifungals. Results: The most recent surgical intervention revealed multiple nodules which were seen on microscopy to have necrotizing granulomatous inflammation. Histochemistry with PAS confirmed a fungal infection and the microbiological study with PCR in formalin-fixed paraffin-embedded tissue identified the pathogen as Cladosporium cladosporioides. Conclusions: To our knowledge, this is the first report of intraabdominal infection due to C. cladosporioides with granuloma formation. The differential diagnosis with other intraabdominal granulomatous is discussed. © 2011 SEAP y SEC.

Puig-Barbera J.,Fund. para El Fomento de la Investigacion Sanitaria Y Biomedica de la Comunitat Valenciana FISABIO | Garcia-De-Lomas J.,Instituto Valenciano Of Microbiologia | Diez-Domingo J.,Fund. para El Fomento de la Investigacion Sanitaria Y Biomedica de la Comunitat Valenciana FISABIO | Limon-Ramirez R.,Hospital de la Plana | And 11 more authors.
PLoS ONE | Year: 2014

Background: Most evidence of the effectiveness of influenza vaccines comes from studies conducted in primary care, but less is known about their effectiveness in preventing serious complications. Here, we examined the influenza vaccine effectiveness (IVE) against hospitalization with PCR-confirmed influenza in the predominant A(H3N2) 2011-2012 influenza season. Methods: A hospital-based, test-negative study was conducted in nine hospitals in Valencia, Spain. All emergency admissions with a predefined subset of symptoms were eligible. We enrolled consenting adults age 18 and over, targeted for influenza vaccination because of comorbidity, with symptoms of influenza-like-illness within seven days of admission. We estimated IVE as (1-adjusted vaccination odds ratio)∗100 after accounting for major confounders, calendar time and recruitment hospital. Results: The subjects included 544 positive for influenza A(H3N2) and 1,370 negative for influenza admissions. Age was an IVE modifying factor. Regardless of vaccine administration, IVE was 72% (38 to 88%) in subjects aged under 65 and 21% (-5% to 40%) in subjects aged 65 and over. By type of vaccine, the IVE of classical intramuscular split-influenza vaccine, used in subjects 18 to 64, was 68% (12% to 88%). The IVE for intradermal and virosomal influenza vaccines, used in subjects aged 65 and over, was 39% (11% to 58%) and 16% (-39% to 49%), respectively. Conclusions: The split-influenza vaccine was effective in preventing influenza-associated hospitalizations in adults aged under 65. The intradermal vaccine was moderately effective in those aged 65 and over. © 2014 Puig-Barberà et al.

This paper reports a new population of Bulinus truncatus (Audouin, 1827) (Gastropoda, Planorbidae) found in the province of Almería (Southeast Spain). B. truncatus is an intermediate host of Schistosoma haematobium, the trematode which causes urinary schistosomiasis in humans. Individuals were identified to species level by double-nested PCR, resulting in 100% homology. This population is located under the driest climate conditions of the Iberian Peninsula. Data on the distribution of this species in the Iberian Peninsula was gathered and is provided in this paper. Improved knowledge of the distribution of Bulinus truncatus is key to assess the risk of new outbreaks of schistosomiasis in the Iberian Peninsula. © 2015 SAM y CSIC.

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