Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul

Lisbon, Portugal

Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul

Lisbon, Portugal
SEARCH FILTERS
Time filter
Source Type

Afonso Costa H.,Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul | Morais P.,Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul | Vieira Da Silva C.,Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul | Matos S.,Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul | And 6 more authors.
Molecular Biology Reports | Year: 2014

Population genetic data of 12 X chromosomal short tandem repeats markers (DXS10074, DXS10079, DXS10101, DXS10103, DXS10134, DXS10135, DXS10146, DXS10148, DXS7132, DXS7423, DXS8378 and HPRTB) were analysed in 54 females and 95 males of an immigrant population from Cabo Verde living in Lisboa. The obtained results for forensic statistical parameters such as observed heterozigosity, polymorphism information content, power of discrimination and mean exclusion chance, based on single allele frequencies, reveal that this multiplex system is highly informative and can represent an important tool for genetic identification purposes in the immigrant population of Cabo Verde. Since the studied short tandem repeats genetic markers are distributed on four linkage groups, that can provide independent genotype information, we studied those groups as haploytes. The forensic efficiency parameters for the linked groups were all higher than 0.97, with linkage group I being the most polymorphic and linkage group III the less informative. © 2014 Springer Science+Business Media Dordrecht.


PubMed | Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Centro, University of Beira Interior and Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul
Type: | Journal: Analytical and bioanalytical chemistry | Year: 2016

Cocaine is still one of the most abused drugs worldwide and, as such, it is often screened for in driving-under-the-influence or workplace drug - testing scenarios. A large number of samples have usually to be processed in those situations, and this requires fast and simple extraction procedures for the detection and quantification of the drugs. The present work describes an ultrafast and fully validated procedure for the simultaneous detection and quantification of cocaine and its two main metabolites, ecgonine methyl ester and benzoylecgonine, in urine using microextraction by packed sorbent and GC-MS. A small sample volume (200L) was used, and a fast extraction procedure together with a microwave-assisted derivatization (800W, 2min) allowed the quantification of all analytes in a range of 25 to 1000ng/mL (r

Loading Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul collaborators
Loading Instituto Nacional Of Medicina Legal E Ciencias Forenses Ip Delegacao Do Sul collaborators