Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia

Valdeolmos, Spain

Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia

Valdeolmos, Spain

Time filter

Source Type

Traves P.G.,La Jolla Salk Institute | Luque A.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | Hortelano S.,Institute Salud Carlos III
Mediators of Inflammation | Year: 2012

The interaction between tumor progression and innate immune system has been well established in the last years. Indeed, several lines of clinical evidence indicate that immune cells such as tumor-associated macrophages (TAMs) interact with tumor cells, favoring growth, angiogenesis, and metastasis of a variety of cancers. In most tumors, TAMs show properties of an alternative polarization phenotype (M2) characterized by the expression of a series of chemokines, cytokines, and proteases that promote immunosuppression, tumor proliferation, and spreading of the cancer cells. Tumor suppressor genes have been traditionally linked to the regulation of cancer progression; however, a growing body of evidence indicates that these genes also play essential roles in the regulation of innate immunity pathways through molecular mechanisms that are still poorly understood. In this paper, we provide an overview of the immunobiology of TAMs as well as what is known about tumor suppressors in the context of immune responses. Recent advances regarding the role of the tumor suppressor ARF as a regulator of inflammation and macrophage polarization are also reviewed. © 2012 Paqui G. Través et al.


Fernandez-Getino A.P.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | Santin-Montanya M.I.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | Zambrana E.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | De Andres E.F.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | Tenorio J.L.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia
Annals of Applied Biology | Year: 2015

Barley is a widespread crop of choice in the Spanish agricultural farming. A 7-year field study was realised to examine the barley yield data. Weather conditions were analysed and taken into account when considering the influence of the tillage systems (TS) and previous crop on barley. In general, barley yield increased with tillage intensity; however the analysis of tiller-count and thousand-grain weight of barley did not present significant differences within the different TS. Barley monoculture presented lower yield than the barley in rotation with fallow or vetch, especially in those years characterised by a greater annual rainfall than average over the 7 years of study (290 mm). Also, we observed that the presence of weeds was strongly influenced by the combined effects of the environmental conditions, TS, and previous crop. It was observed that high rainfall during sowing period or shortly after had a high positive impact on production efficiency and yields. Unexpectedly, the study demonstrated positive correlation between high December temperatures and resulting barley yield. It would be useful to take into account these results when selecting the crop variety for conservation planning in Mediterranean areas. © 2014 Association of Applied Biologists.


Santin-Montanya M.I.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | Martin-Lammerding D.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | Zambrana E.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia | Tenorio J.L.,Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia
Soil and Tillage Research | Year: 2016

The agronomic practices used to manage the soil play an important role in the maintenance of biological diversity within crop fields. Conservation agriculture technology has been extensively adopted in dry land conditions. In these systems, the relationship between soil properties and weed density and soil weed seed bank has not been explored deeply. We conducted this study in order to: (1) examine the cumulative impact of tillage systems (CT, MT and NT) on weed emergence on the field; (2) test the effects of different tillage and crop systems on weed species density and diversity (Shannon's index, Pielou index and species richness) within the transient and persistent seed bank of the soil; and (3) analyse the impact of two soil parameters on weeds: water stable aggregates (WSA) and particulate organic matter content (C-POM). The highest weed density was recorded in conservation tillage systems (MT and/or NT) several years after the implementation of these systems. Additionally, the cumulative effects of conservation tillage techniques were found to have increased the seed density and species diversity in soil seed bank, which was probably due to particular conditions created in the soil; a low or negligible level of soil disturbance (as is expected with MT and NT) possibly allowed seeds to keep in the soil seed bank and remain dormant, due to, among other reasons, improved water stable aggregates and organic matter content. Results from the study confirm the complexity of the matrix formed by weed-seed bank-soil. © 2016 Elsevier B.V.

Loading Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia collaborators
Loading Instituto Nacional Of Investigacion Agraria Y Alimentaria Inia collaborators