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Llanes L.L.,Instituto Nacional Of Endocrinologia
Revista Cubana de Salud Publica | Year: 2011

People suffering from chronic diseases have to deal with them in the physical, psyquical and symbolic spaces of their individuality. However, the human being is a reconstruction of the social and personal image of subjects. Paid or non-paid occupations can be restricted and restructured on account of the need of systematic health care; this may bring about economic instability having an impact on the family structure and dynamics. The family is the source of support par excellence, particularly the couple. Living experience of restricted sexuality might be more the result of how the disease and the experience are built and approached rather than the direct consequence of the process of disease. It is important to explore the life dynamics in persons with chronic diseases within their different areas of expression, and to understand how the actors are involved in their health processes as a way of potentiating well-being, health and quality of life. Source

A descriptive and observational study was conducted in the populations came to "Isidro de Armas" polyclinic from July to November, 2006 to describe the anti-vector fight campaign including the focal treatment, the carrying out and the inspection of at home fumigation and the work quality control together with the inter-sector task and the community involvement. From July to November 66 Aedes Aegypti outbreaks at homes and its surrounding areas were detected. Searching by blocks the relation of confirmed cases of dengue and the Aedes aegypti outbreaks it was possible to demonstrate that in the 83% there was not any relation. Data were collected by Statistic Department and were processed by Epinfo 0,6 in absolute numbers and percentages. We conclude that there was a decrease in the infestation rate with the inter-sector task and community involvement. Source

Chronic diseases are felt as experience with deep impact. This article analyzed the association of the categories body, gender and health-disease on the basis of some dimensions involved in processes of health care given to persons affected by different chronic diseases. The diagnosis of the disease, its multiple manifestations, the chronic condition and some underlying particularities of these processes show, in close relation with meanings and determinants, the complexity of these pieces of experience in health care and its psychosocial sequelae. It is required to maintain equity and participatory perspective in the health processes that support the meanings that the individuals derived from their experience. Source

Gonzalez Calero T.M.,Instituto Nacional Of Endocrinologia
Revista Cubana de Salud Publica | Year: 2013

Type I diabetes mellitus shows long chronic progressive phase that is now predictable in most of individuals. Recent advances in the understanding of autoimmune etiology of this type of diabetes warrant the implementation of novel methods of immunological interventions. This paper was aimed at reviewing the most relevant aspects on the prevention of type I diabetes mellitus and probable strategies. The intervention measures covered the following immunological methods: Deprivation of bovine proteins, plasmapheresis, insulin-based therapy, oral administration of insulin and GAD antigen; use of immunosupressors, immunomodulators and semi-specific immunotherapies. Non-immunological treatments have been used such as use of non-steroidal anti-inflammatory or antioxidant drugs prior to onset of intolerance to glucose, and the presence of vascular complications. Several trials on possible preventive treatments for type I diabetes mellitus are being performed, but none of them has been so far enough safe and efficient in a convincing way; the rational use of new and potent immunosuppresors or immunomodulators is an attractive procedure to prevent the development and progression of the autoimmune process that characterizes this disease in "high risk" individuals. Source

Cabrera-Rego J.O.,Instituto Nacional Of Cardiologia Y Cirugia Cardiovascular | Gandarilla-Sarmientos J.C.,Instituto Nacional Of Cardiologia Y Cirugia Cardiovascular | del Busto-Mesa A.,Instituto Nacional Of Endocrinologia | Valiente-Mustelier J.,Instituto Nacional Of Cardiologia Y Cirugia Cardiovascular
Revista Argentina de Cardiologia | Year: 2012

Background Epicardial fat is currently considered a real endocrine organ that can be easily determined by echocardiography, emerging as a novel parameter for the estimation of cardiometabolic risk. Objective To determine the association between epicardial fat, insulin resistance and carotid intima-media thickness. Methods The Instituto Nacional de Endocrinología and the Instituto Nacional de Cardiología y Cirugía Cardiovascular conducted a cross-sectional study on 239 patients with suspected disorders of carbohydrate metabolism. Clinical variables (age, gender, smoking habits, systolic and diastolic blood pressure), anthropometric measurements (waist circumference and body mass index), biochemical determinations (blood glucose, total cholesterol, HDL-C, LDL-C, triglycerides, fasting insulin levels and HOMA-IR) and echocardiographic variables (carotid intima-media thickness) were included. Results A significant and independent association was found between blood glucose, epicardial fat and waist circumference, in that order, and HOMA-IR >2.6. Epicardial fat also showed a positive and significant correlation with fasting insulin levels (r=0.536; p=0.0001) and HOMA-IR (r=0.512; p=0.001). The correlation between epicardial fat and carotid intimamedia thickness was greater in insulin resistant patients (r=0,523; p=0.0001), compared to patients with HOMA-IR <2.6 (r=0.173; p=0.029). Epicardial fat thickness ≥4.9 mm had a sensitivity of 85% and a specificity of 75% to predict insulin resistance, with an area under the ROC curve of 0.815 (95% CI 0.759-0.871). Conclusions Epicardial fat had a significant an independent association with insulin resistance and a significant correlation with carotid intima-media thickness in the group of patients with HOMA-IR >2.6. Source

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