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Zambrano E.,Instituto Nacional Of Ciencias Medicas Y Nutricion | Nathanielsz P.W.,University of Texas Health Science Center at San Antonio
Nutrition Reviews | Year: 2013

Maternal obesity can profoundly affect offspring phenotype and predisposition to obesity and metabolic disease. Carefully controlled studies in precocial and altricial mammalian species provide insights into the involved mechanisms. These include programming of hypothalamic appetite-regulating centers to increase orexigenic relative to anorexigenic drive; increasing maternal, fetal, and offspring adrenal and peripheral tissue glucocorticoid production; and increasing maternal oxidative stress. Outcomes often show offspring sex differences that may play a role in the differential susceptibility of males and females to later-life obesity and other related metabolic diseases. © 2013 International Life Sciences Institute. Source


Chavarri-Guerra Y.,Massachusetts General Hospital | Chavarri-Guerra Y.,Instituto Nacional Of Ciencias Medicas Y Nutricion | Chavarri-Guerra Y.,Harvard University | Villarreal-Garza C.,Instituto Nacional Of Cancerologia | And 8 more authors.
The Lancet Oncology | Year: 2012

Breast cancer is a major public health issue in low-income and middle-income countries. In Mexico, incidence and mortality of breast cancer have risen in the past few decades. Changes in health-care policies in Mexico have incorporated programmes for access to early diagnosis and treatment of this disease. This Review outlines the status of breast cancer in Mexico, regarding demographics, access to care, and strategies to improve clinical outcomes. We identify factors that contribute to the existing disease burden, such as low mammography coverage, poor quality control, limited access to diagnosis and treatment, and insufficient physical and human resources for clinical care. © 2012 Elsevier Ltd. Source


Patent
Instituto Nacional Of Ciencias Medicas Y Nutricion, Massachusetts General Hospital and Cchmc | Date: 2010-07-02

A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.


Patent
Childrens Hospital Medical Center, The General Hospital Corporation and Instituto Nacional Of Ciencias Medicas Y Nutricion | Date: 2014-09-23

An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewis


Crabtree-Ramirez B.,Instituto Nacional Of Ciencias Medicas Y Nutricion | Del Rio C.,Emory University | Grinsztejn B.,Institute Pesquisa Clinica Evandro Chagas Fundacao Oswaldo Cruz | Sierra-Madero J.,Instituto Nacional Of Ciencias Medicas Y Nutricion
Journal of Acquired Immune Deficiency Syndromes | Year: 2014

The life expectancy of people living with HIV has dramatically improved with the much increased access to antiretroviral therapy. Consequently, a larger number of people living with HIV are living longer and facing the increased burden of noncommunicable diseases (NCDs). NCDs and HIV infection share common epidemiologic and sociodemographic characteristics that influence their outcomes, which may be difficult to address in the relatively weak health systems of the region. Data on the prevalence and interactions of NCDs and HIV in Latin American countries remain very limited, which hinders their governments' ability to make informed decisions about health care policies. Therefore, there is an urgent need to develop a research agenda that will be the basis for an integrated and comprehensive health care approach to HIV and NCD comorbidities in Latin America. © 2014 by Lippincott Williams & Wilkins. Source

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