Institutions of Higher Learning in Guizhou Province

Zunyi, China

Institutions of Higher Learning in Guizhou Province

Zunyi, China

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Lang Y.-L.,Zunyi Medical University | Guan X.-Y.,Zunyi Medical University | Guan X.-Y.,Institutions of Higher Learning in Guizhou Province | Liu J.-G.,Zunyi Medical University | Liu J.-G.,Institutions of Higher Learning in Guizhou Province
Chinese Journal of Tissue Engineering Research | Year: 2015

BACKGROUND: Orthodontic treatment is a mechanical force for tooth to cause the remodeling of periodontal tissue, produced by the tooth movement. The main aspect of orthodontic periodontal tissue remodeling is the alveolar bone. Insulin-like growth factor is an important factor in the remodeling of periodontal tissue, which plays an important role in the growth, differentiation and growth of the cells. OBJECTIVE: To review the role of insulin-like growth factors in periodontal tissue remodeling. METHODS: A computer-based retrieval of PubMed, CNKI and Guizhou Province Digital Library Database was performed to search articles related to the role of insulin-like growth factors in periodontal tissue remodeling. The keywords were "insulin-like growth factor; periodontal tissue; remodeling" in English and Chinese, respectively. RESULTS AND CONCLUSION: Insulin like growth factor belongs to the insulin family, a kind of peptides, which can promote the migration, proliferation, differentiation, collagen and matrix synthesis and alkaline phosphatase activity of osteoblasts, fibroblasts and mesenchymal cells in the periodontal ligament. It also plays an important role in the repair of injury. During orthodontic treatment, the use of suitable orthodontic force combined with insulin-like growth factor can promote periodontal tissue remodeling, accelerate the orthodontic tooth movement and shorten the treatment time for patients. © 2015, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.


Chen Y.-Z.,Zunyi Medical University | Chen Y.-Z.,Institutions of Higher Learning in Guizhou Province | Guan X.-Y.,Zunyi Medical University | Guan X.-Y.,Institutions of Higher Learning in Guizhou Province | And 5 more authors.
Chinese Journal of Tissue Engineering Research | Year: 2014

BACKGROUND: Orthodontic tooth movement is based on the periodontal tissue remodeling. In the exogenous factors accelerating orthodontic tooth movement, Chinese herbal medicine has become a research hotspot because of its wide resources, low cost, easy to extract, mild effect, small toxic, less side effects and drug resistance. OBJECTIVE: To summarize the role of Chinese herbal medicine in the periodontal tissue remodeling during orthodontic tooth movement. METHODS: A computer-based retrieval of CNKI, Wanfang and PubMed databases was performed for articles related to Chinese herbal medicine for improving orthodontic tooth movement published before 2014. The keywords were “Chinese herbal medicine, orthodontic tooth movement, periodontal tissue remodeling” in Chinese and English, respectively. RESULTS AND CONCLUSION: Erigeron breviscapus, Salvia, teasel, Drynaria, baicalin, evening primrose oil as Chinese herbs are most widely used in the promotion of periodontal tissue remodeling, characterized as wide resources, low cost, easy to extract, mild effect, low toxicity, less drug resistance. In the clinical orthodontic treatment, it is hoped to accelerate orthodontic tooth movement and shorten the treatment time. Therefore, under the appropriate corrective force, Chinese herbs can be used properly to improve periodontal tissue repair and remodeling, which can improve the microcirculation of periodontal tissue, increase the local blood flow, promote bone formation and repress bone resorption. © 2014, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.

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