Zdravkovic S.,Institute za Nuklearne Nauke Vinca |
Sataric M.V.,University of Novi Sad
Journal of Biosciences | Year: 2012
We rely on the helicoidal Peyrard-Bishop model for DNA dynamics. Interaction between nucleotides at a same site belonging to different strands is modelled by a Morse potential energy. This potential depends on two parameters that are different for AT and CG pairs, which is a possible source for inhomogeneity. It was shown recently (Zdravković and Satarić 2011) that certain values of these parameters bring about a negligible influence of inhomogeneity on the solitonic dynamics. We propose an experiment that should be carried out in order to determine the values of both of these parameters. © Indian Academy of Sciences. Source
Agency: Cordis | Branch: FP7 | Program: CP-CSA | Phase: Fission-2013-3.1.1 | Award Amount: 10.26M | Year: 2013
Within the OPERRA project, it is proposed that the MELODI Association, as a well-advanced network, takes the lead in establishing the necessary structures able to manage the long-term European research programmes in radiation protection, also taking advantage of the valuable experience gathered through the DoReMi network of excellence. Whilst in fields adjacent to low-dose risk research (radioecology, nuclear emergency management) scientific issues would continue to be hosted by the sister associations, Alliance and NERIS, these associations are encouraged to join MELODI to establish an umbrella structure as equal partners. OPERRA will exploit the synergies of EURATOM and other EC programmes considering the most relevant joint program areas and mechanisms for funding joint activities. The project will also strengthen the links with national funding programs as well as the European education and training structures. Also, it will take steps towards a greater involvement of those new Member States who could benefit from increased participation in the radiation research programmes. Finally, OPERRA will take steps to further integrate the joint use of infrastructures in European countries, and to develop and facilitate an easier access to research infrastructures. The final objective of this project is to build up an umbrella coordination structure that has the capacity in a legal and logistical sense to administer future calls for research in radiation protection as a whole (including low-dose risk, radioecology, nuclear emergency management, and also research activities related to the medical uses of ionizing radiation) on behalf of the European Commission. OPERRA will prepare the organisation for a first competitive call by the end of 2013 for projects in low-dose risk research and a second competitive call in 2014 for broader projects in radiation protection research, subject to the approval of EC services, with the support of Go-between administrator operator and an external advisory entity.
Agency: Cordis | Branch: FP7 | Program: CP-FP | Phase: KBBE-2009-2-7-01 | Award Amount: 1.94M | Year: 2010
A number of epidemiological studies have consistently demonstrated the protective effects of fruits and vegetables with respect to several age related diseases. The aim of this project is to investigate the protective action of agents with potential use as functional food constituents with respect to cancer, diabetes and cardiovascular disease. In collaboration between EU and Indian research centers the proposal features a multipronged approach, where the protective action of various non-toxic agents are studied in vitro as well as in rodent models with respect to induction of DNA lesions, tumours and biomarkers for the development of diabetes, diabetic retinopathy and atherosclerosis. In addition, reduced availability of carcinogens and inhibition of their metabolic activation are investigated. Testing of the protective efficacy of functional food components in intervention cross-over studies in humans exposed to carcinogens, that are normally present at significant levels in the environment, represents an approach that has rarely been resorted to, and will be implemented under this project in Europe as well as in India using sophisticated molecular, cytogenetic and other analytical methods. Although there has been remarkable progress in our understanding of the processes that lead to neoplasia and diabetes, the mechanisms underlying chemoprevention are, in general, little understood. The results from this project are expected to provide an improved insight with respect to this topic.
Agency: Cordis | Branch: FP7 | Program: CSA-SA | Phase: ERACHAIRS-2013-1 | Award Amount: 2.80M | Year: 2014
Through the realization of MagBioVin project, the Institute of Nuclear Sciences Vinca, University of Belgrade (Serbia) receives important community support to upgrade its capacities related to the highly specialized research on activated magnetic nanoparticles (MNP) and radionuclide labeled magnetic nanoparticles for application in biosciences, pharmacy and medicine. This is planned to be realized by a set of comprehensive actions, such as engagement of eminent expert in the field (ERA Chair holder), bringing experimental facilities up to the most advanced EU-competitive level, cutting-edge trainings in reputable EU research institutions and intensive dissemination towards ERA, Universities and stakeholders. The Project foresees the key role of ERA Chair holder in improvement of organizational structure, research excellence and especially in communication with stakeholders. Organization of seven dedicated international workshops led by EU experts in the field, six extensive training programs for MagBioVin team members and the accent on intensified international collaboration, are few of the activities anticipated through Project implementation. These are designed to set solid foundations for a final goal: to rise both human and experimental capacities of the Vinca Institute to the level that ensures considerable scientific and technological impact within ERA and its ability to compete with leading EU research institutions on an equal basis.
Agency: Cordis | Branch: FP7 | Program: CP | Phase: ENV.2012.6.5-1 | Award Amount: 12.70M | Year: 2012
CITI-SENSE will develop citizens observatories to empower citizens to contribute to and participate in environmental governance, to enable them to support and influence community and societal priorities and associated decision making. CITI-SENSE will develop, test, demonstrate and validate a community-based environmental monitoring and information system using innovative and novel Earth Observation applications. To achieve this, the project will: (i) raise environmental awareness in citizens, (ii) raise user participation in societal environmental decisions and (iii) provide feedback on the impact that citizens had in decisions. It will address the calls request for effective participation by citizens in environmental stewardship, based on broad stakeholder and user involvement in support of both community and policy priorities. The project aims to learn from citizen experience and perception and enable citizenship co-participation in community decision making and co-operative planning. The concept of CITI-SENSE rests on three pillars: technological platforms for distributed monitoring; information and communication technologies; and societal involvement. Three pilot case studies will focus on a range of services related to environmental issues of societal concern: combined environmental exposure and health associated with air quality; noise and development of public spaces, and indoor air at schools. Attention will be given to representativeness of citizen participation. The case studies will be designed in collaboration with citizens groups and decision makers. They will be based on distributed data collection using innovative static, portable and personal devices (low-cost reliable microsensor packs) that communicate with a data repositories through mobile phones or other devices. Development of participatory methods, data management strategies, and applications to facilitate exploitation of the data and information for policy, and society, will be done.