Institute Pesquisas Cientificas e Tecnologicas do Amapa

Macapá, Brazil

Institute Pesquisas Cientificas e Tecnologicas do Amapa

Macapá, Brazil
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Medeiros A.A.N.,Institute Pesquisas Cientificas e Tecnologicas do Amapa | Medeiros F.A.,Institute Pesquisas Cientificas e Tecnologicas do Amapa | Queiroz T.M.,Federal University of Paraiba | Tavares J.F.,Institute Pesquisas Cientificas e Tecnologicas do Amapa | And 2 more authors.
Brazilian Journal of Pharmacognosy | Year: 2010

Pradosia huberi (Ducke) Ducke (Sapotaceae), an Amazonian species, is popularly known as "casca-doce" and used in the folk medicine for the treatment of gastritis. The ethanol extract of the bark contains mainly polyphenolic compounds, which are known to show a large number of activities, including cardioprotective and vasorelaxant effects. The aim of this study was to evaluate the pharmacological properties induced by P. huberi ethanol extract (PHEE) and fractions and 2-3-dihydromyricetin-3-O-α-L-rhamnoside derived from this extract, in isolated rat mesenteric arteries. PHEE was separated and the following fractions were obtained: CHCl3, CHCl3:AcOEt (1:1), AcOEt, AcOEt:MeOH (1:1) and MeOH. We isolated 2-3-dihydromyricetin- 3-O-α-L-rhamnoside from the MeOH fraction, which was identified by 1H and 13C NMR spectra and compared with data in the literature. PHEE (1-100 μg/mL) induced concentration-dependent relaxations of 10 μM phenylephrine-induced tone (EC50 = 17, 1±2,9 μg/mL; Emax = 87.4±2.9 %, n=8). The MeOH fraction also relaxed mesenteric rings (EC50 = 31±2.0 μg/mL; Emax = 54±12.5%, n=6) but less effectively when compared to PHEE. Both effects were completely abolished after removal of the vascular endothelium. The AcOEt:MeOH (1:1) fraction and the isolated flavonoid were ineffective in eliciting vasorelaxation. The study demonstrates that PHEE and MeOH fraction of Pradosia huberi possess a vasorelaxant effect, which may be completely dependent upon endothelium. The isolated flavonoid is not responsible for this vasorelaxant effect.


Lemos L.D.N.,Federal University of Amapá | Deus E.D.G.D.,Federal University of Amapá | Nascimento D.B.D.,Federal University of Amapá | Jesus-Barros C.R.D.,Embrapa Amapa | And 2 more authors.
Florida Entomologist | Year: 2017

Fruit flies and associated parasitoids were determined in native and introduced fruit species in the state of Amapá, Brazil. Fruits were collected every 30 d, from Jan to Dec 2012, on 3 small farms in the municipalities of Mazagão, Porto Grande, and Santana. We collected 412 samples (78 species of plants belonging to 32 families and consisting of 4,554 fruits weighing 323.4 kg) and obtained 5,252 Anastrepha (Diptera: Tephritidae) puparia from 107 infested samples (20 plant species from 13 botanical families). We report here the occurrence of 11 species of Anastrepha and 5 species of parasitoids (4 Braconidae and 1 Figitidae species; both families in the order Hymenoptera). New hosts for Anastrepha distincta Greene, Anastrepha leptozona Hendel, Anastrepha obliqua (Macquart), and Anastrepha serpentina (Wiedemann) were documented in Brazil.


Martins A.C.M.,Institute Pesquisas Cientificas e Tecnologicas do Amapa | Bernard E.,Federal University of Pernambuco | Gregorin R.,Federal University of Lavras | da Silva W.A.S.,Institute Pesquisas Cientificas e Tecnologicas do Amapa
Zoologia | Year: 2011

Brazil is the second most bat species-rich country in the world, but the information on its species diversity, occurrence and distribution is still heterogeneous and fragmented. None of the Brazilian biomes are well surveyed for bats, but this situation is more critical in Amazonia, an area covering nearly 2/3 of the country. Here we provide updated information on the bats of Amapá, once a data gap in the diversity and distribution of bats in the easternmost Amazonia, and the Guiana Shield as well. Rapid biological assessments (5,551 mistnet.hours) were conducted in conservation units and areas of concern, resulting in 1,695 captures, 59 species, 36 genera and six families for the State. New records for the state and for the Guiana Shield area are reported. With our records, 82 species of bats are currently known in Amapá, filling a gap in the knowledge of bat fauna in the Amazon River's delta region. © 2011 Sociedade Brasileira de Zoologia. All rights reserved.


Almeida R.D.R.,Federal University of Amapá | Sousa M.D.S.M.D.,Federal University of Amapá | Costa-Neto S.V.D.,Institute Pesquisas Cientificas e Tecnologicas Do Amapa | Jesus-Barros C.R.D.,Embrapa Amapa | And 2 more authors.
Florida Entomologist | Year: 2016

We conducted a survey of the species of frugivorous flies (Tephritidae and Lonchaeidae), their hosts, and their parasitoids found on Ilha de Santana, Amapá State, Brazilian Amazon. We also assessed host plant use by Bactrocera carambolae Drew & Hancock. Fruits were collected from various plant species, at 30 d intervals, from Jan to Jul 2015. In total, 149 fruit samples were collected (3,142 fruits, 76.3 kg), belonging to 20 plant species (9 native and 11 introduced) in 13 botanical families. Infestation by fruit flies was observed in 86 samples (11 species in 8 botanical families). Specimens of 5 species of Tephritidae and 4 species of Lonchaeidae fruit flies were obtained, as well as 3 species of braconid parasitoids. The most important fruit fly species on Ilha de Santana are: B. carambolae, for being a species of quarantine importance; and Anastrepha obliqua (Macquart) and Anastrepha striata Schiner, for infesting plant species of local socioeconomic importance. Averrhoa carambola (Oxalidaceae), Eugenia uniflora (Myrtaceae), Malpighia emarginata (Moc. & Sesse) ex DC. (Malpighiaceae), and Psidium guajava (Myrtaceae) are the host plants responsible for sustaining the population of B. carambolae.


Santos M.F.G.,Institute Pesquisas Cientificas e Tecnologicas do Amapa | Alves R.E.,Embrapa Agroindustria Tropical | Roca M.,Pablo De Olavide University
Grasas y Aceites | Year: 2015

The oils obtained from native palm fruits are considered new sources of high added value phytochemicals, making it necessary to know the composition of the less studied species in order to evaluate their economic potential. The objective of this study is to identify and quantify the carotenoids in palm fruit oils from the Brazilian Amazon: bacaba (Oenocarpus bacaba), buriti (Mauritia flexuosa), inajá (Maximiliana maripa), pupunha (Bactris gasipaes) and tucumã (Astrocaryum vulgare), by means of liquid phase extraction and HPLC-UV-vis. analysis. The results showed an extremely variable carotenoid content, from 13 mg·kg-1 in bacaba oil to more than 1000 mg·kg-1 in the tucumã one. The oils obtained from buriti, pupunha and tucumã displayed high concentrations of β-carotene, corresponding to fruits with the series β, β dominant metabolism. Upon analyzing the carotenoid profile in bacaba oil for the first time, an extraordinary dominance of the β, ε pathway was observed, proving them to be oils with high lutein and α-carotene contents. Although the β, β pathway dominates in inajá oil, the exclusive and high lycopene content implies that LCY-E is barely active in these fruits, in contrast to what has been evidenced so far. It is therefore of the utmost importance to characterize these new potential sources of carotenoids. © 2015 CSIC.


Braganca P.H.N.,Federal University of Rio de Janeiro | Costa W.J.E.M.,Federal University of Rio de Janeiro | Gama C.S.,Institute Pesquisas Cientificas e Tecnologicas do Amapa
Ichthyological Exploration of Freshwaters | Year: 2011

Poecilia waiapi, new species, is described from the lower Jari river drainage, in northern Brazil. It is hypothesized to be closely related to P. branneri, P. minima and P. sarrafae by sharing eight apomorphic conditions. Poecilia waiapi differs from all of its congeners by the presence of vertical dark gray bars on the flank in males (vs. bars absent in P. bifurca, P. picta and P. parae; vertical pale gray bars in P. sarrafae, P. minima and P. branneri); post-humeral blotch densely pigmented (vs. post-humeral blotch absent in P. branneri, post-humeral blotch slightly pigmented in P. sarrafae, P. minima, P. picta, P. bifurca, P. parae). © 2011 by Verlag Dr. Friedrich Pfeil.


De Medeiros F.A.,Institute Pesquisas Cientificas e Tecnologicas Do Amapa | Medeiros A.A.N.,Federal University of Paraiba | Tavares J.F.,Federal University of Paraiba | Filho J.M.B.,Federal University of Paraiba | And 2 more authors.
Quimica Nova | Year: 2012

The phytochemical investigation of L. macrophylla Benth led to the isolation of a new flavanol named licanol: (-)-4'-O-methyl-epigallocatechin-3'- O-?-L-rhamnoside, along with nine known compounds, identified as: (-)-4'-O-methyl-epigallocatechin, pheophytin A, 132-hydroxy-(132-S)-pheophytin A, pheophytin B, sitosterol, stigmasterol, sitosterol-β-O-glucoside, betulinic alcohol and oleanolic acid. The structures were established based on IR, HR-ESI-MS, and NMR spectrometric data analysis with the aid of 2D techniques. The methanolic extracts of leaves and stem bark as well as the compounds licanol, 132-hidroxi-(132-S)-feofitina A, and betulinic alcohol demonstrated antimicrobial activity against several bacterial strains.

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