Conde, Mexico
Conde, Mexico

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Ellen Sy M.,University of California at Los Angeles | Ramirez-Miranda A.,Institute Oftalmologia | Zarei-Ghanavati S.,Mashad University of Medical science | Engle J.,Aurora University | And 2 more authors.
Journal of Refractive Surgery | Year: 2013

PURPOSE: To compare the maximum posterior elevation (MPE) measurements before and after LASIK using a dual rotating Scheimpflug (DRS) imaging system (Galilei, Ziemer Ophthalmic Systems, Port, Switzerland) and a scanning slit-beam (SSB) imaging system (Orbscan IIz, Bausch & Lomb, Rochester, NY). METHODS: This retrospective study included 78 eyes from 78 patients who underwent myopic LASIK. Preoperative and postoperative data collected included anterior and posterior best-fit sphere radius and axial curvature readings, posterior central elevation (PCE), and MPE relative to a best-fit sphere using a 7.8-mm region of interest. Data were compared using paired t test analysis. RESULTS: Mean preoperative PCE (5.06 ± 2.29 μm with the DRS system and 12.78 ± 6.90 μm with the SSB system) and MPE (4.87 ± 4 μm with the DRS system and 15.44 ± 9.78 μm with the SSB system) were statistically different (P < .001). Mean postoperative PCE (4.55 ± 2.34 μm with the DRS system and 20.59 ± 8.11 μm with the SSB system) and MPE (4.90 ± 3.35 μm with the DRS system and 24.95 ± 10.15 μm with the SSB system) were statistically different (P < .001). The difference between preoperative and postoperative MPE measurements by DRS was not statistically significant (P = .953), whereas the difference measured by SSB was statistically significant (P < .001). CONCLUSIONS: The consistency of DRS measurements suggests that the posterior surface of the cornea does not change appreciably after keratorefractive surgery and is imaged more accurately using DRS compared with SSB. The DRS system affords confidence in interpreting data that are useful for discerning morphologic abnormalities of the cornea, both before and after keratorefractive surgery. Copyright © SLACK Incorporated.

PubMed | Antiguo Hospital Civil Of Guadalajara Fray Antonio Alcalde, Laboratorios Sophia SA, Institute Oftalmologia, Fundacion Hospital Nuestra Senora Of La Luz and Hospital Dr Luis Sanchez Bulnes
Type: | Journal: Clinical ophthalmology (Auckland, N.Z.) | Year: 2016

The purpose of this study was to evaluate the aqueous humor bioavailability and clinical efficacy of bromfenac 0.09% vs nepafenac on the presence of cystoid macular edema (CME) after phacoemulsification.A Phase II, double-blind, masked, active-controlled, multicenter, clinical trial of 139 subjects, randomized to either a bromfenac 0.09% ophthalmic solution (n=69) or nepafenac 0.1% (n=70). Subjects instilled a drop three times a day for a period of 30 days. Follow-up visits were on days 2, 7, 15, 30, and 60. Biomicroscopy, clinical ocular signs, and assessment of posterior segment were performed. The primary efficacy endpoints included the presence of CME evaluated by optical coherence tomography. Safety evaluation included intraocular pressure, transaminase enzymes, lissamine green, and fluorescein stain.The demographic and efficacy variables were similar between groups at baseline. The presence of pain, photophobia, conjunctival hyperemia, chemosis, cellularity, and corneal edema disappeared by day 30 in both groups. The central retinal thickness did not show significant changes after treatment when compared to baseline as follows: in the bromfenac group (247.232.9 vs 252.024.9 m; P=0.958) and in nepafenac group (250.834 vs 264.034.1 m; P=0.137), respectively. A statistically significant difference was observed between bromfenac and nepafenac group: (252.024.9 vs 264.034.1 m; P=0.022), at day 30, respectively; even though there was no clinical relevance in the presentation of CME. There were no significant alterations in intraocular pressure, either lissamine green or fluorescein stains. The adverse events were not related to the interventions.Bromfenac 0.09% ophthalmic solution showed similar clinical efficacy to reduce the presentation of CME after phacoemulsification compared to nepafenac 0.01%.

Garcia-Rojas L.,Institute Oftalmologia | Adame-Ocampo G.,National Autonomous University of Mexico | Alexanderson E.,National Autonomous University of Mexico | Tovilla-Canales J.L.,Institute Oftalmologia
Journal of Ophthalmology | Year: 2013

Objective. To compare 18-fluorodeoxyglucose (FDG) uptake by positron emission tomography (PET) in extraocular muscles (EOMs) of patients with Graves' ophthalmopathy (GO) versus patients without GO. Design. Prospective, observational, comparative, and cross-sectional study. Participants. Thirty-two eyes of patients with GO and seventy eyes of patients without GO. Methods. We prospectively included patients older than 18 years of age with and without GO. FDG-PET imaging study was performed; standardized unit value (SUVmax) was quantified in EOMs. Standard deviation and significant statistical difference (P<0.05) were calculated. Results. Thirty-two eyes of sixteen patients of the GO group were included, with a mean age of 44.31 (20-71) years. Seventy eyes of thirty-five patients of the group without GO were included, with a mean age of 49.20 (24-77) years. EOMs average uptake of the groups with and without GO were 3.38 ± 1.31 and 1.89 ± 0.51 SUVmax (P<0.05), respectively. Conclusion. FDG uptake was significantly increased in EOMs of patients with GO. PET gives valuable information and may be a helpful tool in detecting, localizing, and quantifying GO inflammation. Further research is needed to define the role of PET in detecting, grading, and following up GO in order to optimize treatment in the inflammatory stage. © 2013 Leonardo García-Rojas et al.

PubMed | Institute Oftalmologia < > and National Autonomous University of Mexico
Type: | Journal: Archivos de la Sociedad Espanola de Oftalmologia | Year: 2016

To report a familial case of Familial Exudative Vitreoretinopathy (FEVR) with an autosomal dominant inheritance pattern identified with the molecular analysis of FZD4.The proband is a 13 year-old boy who consulted for low vision. Fundus examination revealed a peripheral avascular zone and macular dragging, consistent with FEVR. Molecular analysis demonstrated a mutation of FZD4 in DNA from both the patient and his asymptomatic mother.This familial case was identified with the molecular analysis of FZD4 and shows the importance to explore first degree relatives in a sporadic FEVR case.

Valdez-Garcia J.E.,Monterrey Institute of Technology | Climent A.,Institute Oftalmologia | Chavez-Mondragon E.,Institute Oftalmologia | Lozano-Ramirez J.F.,Monterrey Institute of Technology
BMC Ophthalmology | Year: 2014

Background: The incidence of postoperative endophthalmitis has reduced during last several years to <0.01%; however, its associated complications continue to be devastating. Several sources of infection, including contamination by air, solutions, surgical instruments, intraocular lens, and wound leakage have been identified. The objective of this study was to evaluate the surgical technique, antibiotics, and asepsis that are used to reduce the risk of infection during cataract surgery. Methods. This was a transversal prospective study, in which 64 cataract surgeries were evaluated from 32 patients, with 1 month recovery time; and cultures from preoperative and postoperative aspirates were analyzed. Two groups were established based on whether preoperative antibiotics were given or not. The analysis employed descriptive statistics. Results: Of the 32 patients whose aspirates were obtained, three (9.37%) and 10 (31.25%) yielded positive cultures preoperative and postoperatively respectively. Staphylococcus species was the most common contaminating bacteria. The isolation of Staphylococcus species may indicate its potential as exogenous contaminant at time of wound closure. The cultures obtained from patients using preoperative antibiotics were positive for S. aureus in 10% (n = 2) of cases, and positive in 8.33% (n = 1) of cases not using antibiotics. The mean transoperative time with positive growth was 67 ± 17.8 minutes, and with negative growth was 76.3 ± 25.2 minutes. Two surgical techniques were evaluated: phacoemulsification and extracapsular extraction. The extracapsular technique showed a contamination rate of 33.33% (n = 8) compared to phacoemulsification with a rate of 25% (n = 2) (RR = 1.33). Conclusions: Common contaminating microorganisms included the Staphylococcus species, which was isolated from the eyelids and ocular annexes at the time of wound closure. The isolation of microorganisms postoperatively could have been influenced by the surgical technique used, the surgical time, and the use of antibiotics. © 2014 Valdez-García et al.; licensee BioMed Central Ltd.

Gonzalez Rubio-Medina E.,Institute Oftalmologia | Pedroza-Seres M.,Institute Oftalmologia
Archivos de la Sociedad Espanola de Oftalmologia | Year: 2013

Introduction: Pars planitis is an intermediate uveitis with bilateral and asymmetric presentation. The etiology is unknown and pathogenesis is unclear. Treatment follows the algorithm of Foster, which includes selective photocoagulation. The mechanism of action of photocoagulation is still unknown. Material and methods: An observational, longitudinal, ambispective cohort study was performed with the objective of evaluating the course of inflammation in patients with pars planitis treated with a selective argon laser. Results: The study included 29 patients (10 female and 19 male) diagnosed with pars planitis and were treated with selective laser. The mean age of onset was 11.77 years. Eighteen (62.1%) patients were not immunosuppressed at the time of receiving the selective laser, and 11 (37.9%) were taking immunosuppressants. Indications for selective laser were; following the algorithm, 19 (65.55%), vitreous hemorrhage 7 (24.1%), vitrectomy 2 (6.98%), and neovascularization 1 (3.4%). The mean time for inflammation reduction was 5.9 months, and 17 patients (58.6%) had no relapse. Visual acuity showed improvement post-laser (OD P =.025 and OI P =.022). There was also an improvement in vitreous cells. Conclusion: Selective laser was effective in 58.6%% of patients. © 2012 SociedadEspã nola deOftalmología.Publishedby Elsevier Espaãa,S.L.Allrights reserved.

PubMed | Institute Oftalmologia < >
Type: Journal Article | Journal: Archivos de la Sociedad Espanola de Oftalmologia | Year: 2016

The case concerns a 34 year-old man, who presented with pain in the medial canthus in his left eye, with proptosis and diplopia. The examination showed exophthalmus and a palpable mass at the inner canthus. The computed tomography revealed a lesion, which was confirmed by biopsy to be a ossifying fibroma.Ossifying fibroma is a benign fibro-osseous lesion that mostly affects the jaw. Clinical presentation and complications vary according to its location. Clinical examination, imaging, and histopathology are essential for definitive diagnosis. Surgical treatment is multidisciplinary and long-term follow up is needed.

PubMed | Institute Oftalmologia < >
Type: | Journal: Gaceta medica de Mexico | Year: 2015

There are different etiologies related to glaucoma, with the involvement of different systems in the origin and development of the disease.We performed a literature review.The data is divided, with an emphasis on five main topics: systemic disease, neurodegenerative disease, genetic disease, immunological disease, and aging of the trabecular meshwork. Older and recent important findings of each subject are reported to establish a relationship with glaucoma, and mention is made of some of the current research lines.Glaucoma is a multifactorial disease with complex interaction of events at various levels of the organism. Study of the etiology should guide the search for new therapies.

PubMed | Institute Oftalmologia < >
Type: Journal Article | Journal: Archivos de la Sociedad Espanola de Oftalmologia | Year: 2015

A retrospective analysis was performed using the medical records in a referral center in Mexico over a period of 5 years, in order to determine the frequency of acute follicular conjunctivitis.A total of 859,986 ophthalmology consultations were given, from which 8,930 were diagnosed with acute follicular conjunctivitis (1.03% of the total). The number of patients diagnosed range between 100 and 200 in the majority of months. In August 2012 an increase was observed with 308 cases, and then decreasing after two months. This study did not demonstrate a highest frequency by month, with exception of year 2012 that showed a peak incidence in the third trimester.

PubMed | Institute Oftalmologia < >
Type: | Journal: Archivos de la Sociedad Espanola de Oftalmologia | Year: 2016

A 43 year-old woman consulted due to 2 months of swelling on the superolateral side of the left orbit, with pain and erythema. An excisional biopsy was performed that revealed vasculitis with polyangiitis of the lacrimal gland. A systemic study showed that no other system was compromised.Orbital involvement occurs in up to 60% of patients with granulomatosis with polyangiitis. The involvement of the lacrimal gland is rare and often unilateral. Serological tests are generally negative, both in initial stages, as in localized forms of the disease.

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