Sun X.Y.,Institute of Transplant Medicine |
Sun X.Y.,303 Hospital Of Peoples Liberation Army |
Dong J.H.,Institute of Transplant Medicine |
Qin K.,Institute of Transplant Medicine |
And 7 more authors.
Experimental and Therapeutic Medicine | Year: 2016
Effective use of all available donated organs is critical, in order to meet the increasing demand for transplants. The present study explored liver transplantation with livers that were donated following cardiac death (DCD). According to the guidelines established by The Red Cross Society of China, 42 DCD organs were procured. Selected donors were treated with extracorporeal membrane oxygenation (ECMO) prior to the organ retrieval. The present single center study included 6 liver transplantations of DCD organs (5 liver transplants and 1 liver kidney combined transplant). All 6 recipients had a successful recovery without significant complications. The serum alanine transaminase, total bilirubin and international normalized ratio returned to the normal levels within a short period of time following transplantation, and the liver function remained normal during the follow up period, which lasted up to 24 months. The present report demonstrated the feasibility of orthotopic liver transplantation using DCD livers. The pre conditioning DCD donors and optimization of the recipient's condition using ECMO, played a crucial role in ensuring the success of transplantation. © 2016, Spandidos Publications. All Rights reserved.