Nizhniy Novgorod, Russia
Nizhniy Novgorod, Russia

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Lyubavina N.A.,Nizhny Novgorod State Medical Academy | Varvarina G.N.,Nizhny Novgorod State Medical Academy | Makarova E.V.,Nizhny Novgorod State Medical Academy | Menkov N.V.,Nizhny Novgorod State Medical Academy | And 7 more authors.
Sovremennye Tehnologii v Medicine | Year: 2011

The aim of the study is to find out if there is a correlation between the serous level of the soluble forms of sCD50, sCD54 adhesion antigens and clinical, laboratory and microbiological indices in patients with a chronic obstructive pulmonary disease (COPD). Materials and methods. 55 patients with a COPD have been examined. They have undergone general clinical examination, spirometry, microbiological study of sputum. A serous content of the sCD50, sCD54 has been detected with an immunoenzymatic method. The results have been compared with the serum samples of the 16 healthy donors. Results. The research has revealed a correlation between the bacterial dissemination degree and lung functional parameters. It confirms the role of chronic bacterial colonization in a COPD progress. The decrease of the serous level of the adhesion antigens correlates with a higher microbic colonization of the lower respiratory tracts. It points to the disturbance of the immunocompetent cell adhesion mechanism in the COPD pathogenesis. The study has revealed the decrease of the adhesion molecule serous content in a process of the COPD patient treatment. This proves to have an unfavorable effect of the antibiotic and systemic glucocorticosteroid therapy on the immunocompetent cell adhesion processes.


Ryzhov M.K.,City Clinical Hospital No33 | Kosolapov A.G.,City Clinical Hospital No33 | Mudrova S.A.,City Clinical Hospital No33 | Bederina E.L.,City Clinical Hospital No33 | Romanov E.I.,Institute of the FSS of Russia
Sovremennye Tehnologii v Medicine | Year: 2010

A case of the Crohn's disease acute attack, not earlier diagnosed, in a patient with a peroral poisoning with electrolyte is described. A subtotal resection of a stomach, subtotal colectomy with extraction of a greater omentum and resection of the ileum distal department are made because of the critical alterations of the stomach, large intestine and distal departments of the ileum. A patient's state in 9 months after operation was assessed as a satisfactory one.


Artifexov S.B.,Institute of the FSS of Russia | Sergeev M.Y.,Institute of the FSS of Russia | Borodacheva I.V.,Institute of the FSS of Russia | Artifexova M.S.,Nizhny Novgorod State Medical Academy
Sovremennye Tehnologii v Medicine | Year: 2011

Reproductive potential of men is assessed according to spermatograms results obtained relying on macro- and microscopic investigation of sperm sample. This approach does not make it possible to have integral index that is equivalent to healthy reproductive potential of a man as spectrogram indexes are compared separately with percent characteristics of normal standards. The authors suggest calculating only active mobile and morphologically saved sperm cells after their pre-separation using floating up and centrifugation method in concentration gradient. It enables to have the index of absolute gamete number in 1 ml of ejaculate. The fertility threshold is the presence of gametes able to be fertilized (mobile and morphologically saved), 5 mn/ml in number. If the number of gametes is lower than the threshold, other diagnostic tests and therapeutic modalities are required, while threshold elevation gives the evidence of man's potential fertility.


Shevchenko E.A.,Nizhny Novgorod State Medical Academy | Artifexova A.A.,Nizhny Novgorod State Medical Academy | Artifexov S.B.,Institute of the FSS of Russia | Uspenskaya O.A.,Nizhny Novgorod State Medical Academy | Semyonychev A.V.,Ministry of public health of the Nizhny Novgorod region
Sovremennye Tehnologii v Medicine | Year: 2010

Aim of investigation is revealing of the blood general clinical analysis differences in values at the reproductive system different states in females of a child-birth age. Materials and methods. The modern unified methods and hematological analyzer were used for a blood analysis. Results. It is established, that the statistically significant differences in the blood general analysis values are observed at the several physiological and pathologic states of the child-birth age female reproductive system. These differences frequently reflect the peculiarities of the organism physiological and pathologic reactions.


Eliseeva T.I.,Institute of the FSS of Russia | Kulgina Y.S.,Nizhny Novgorod State Medical Academy | Prakhov A.V.,Institute of the FSS of Russia | Konyshkina T.M.,Nizhny Novgorod State Medical Academy
Sovremennye Tehnologii v Medicine | Year: 2010

Aim of investigation is establishment of the exhaling air condensate (EAC) pH alteration regularity in children with different level of a bronchial asthma control, assessed with a use of the ACQ day and week scales (Asthma Control Questionnaire). Materials and methods. The exhaling air condensate pH meanings (without deaeration and after the argonome deaeration) are analyzed in 55 children with different level of a bronchial asthma control, in a disease dynamics in part of them. Results. The pH meaning differences in patients with different level of a bronchial asthma control are not revealed at investigation of the EAC pH without the argonome deaeration (p=0.76 - at assessment of a control level according to the ACQ day scale and p=0.48 - at assessment according to week ACQ scale). A progradient decrease of meanings with aggravation of a bronchial asthma control level, assessed according to the ACQ day scale (p=0.0001), is established at investigation of the EAC pH after the argonome deaeration.

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