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Liu J.,Institute of Reproductive and Child Health Ministry of Health | Jin L.,Institute of Reproductive and Child Health Ministry of Health | Zhang Y.,Institute of Reproductive and Child Health Ministry of Health | Zhang L.,Institute of Reproductive and Child Health Ministry of Health | And 4 more authors.
Birth Defects Research Part A - Clinical and Molecular Teratology | Year: 2015

Background: The aim of this study was to evaluate the relationship between tea consumption and plasma folate concentration in populations with high and low prevalence of neural tube defects (NTDs) in China. Methods: Cross-sectional survey was conducted in three cities/counties in China, in which 1724 pregnant women during early second trimester were recruited and interviewed about tea consumption and folic acid use in 2011 to 2012. A total of 5-ml nonfasting blood sample was collected and plasma folate concentration was determined by microbiological assay. Results: Approximately 16.2% of the women reported that they had ever drank tea during and before the current pregnancy, women with higher educational level, and those who resided in urban were more likely to drink tea. Most of them prefer green tea (55.2%); 13.6% of women drank tea ">6 times/week," and 29.0% of them drank "less than once a week." The median of plasma folate concentration was 48.7 nmol/L in women who drank tea while it is 45.2 nmol/L in women who did not drink tea, with no statistical difference. The results showed there was no association between tea drinking and plasma folate concentration in Chinese pregnant women stratified by folic acid supplementation and other selected characteristics. Conclusion: Low level of tea drinking is not associated with decreased plasma folate concentration in the Chinese populations with high and low prevalence of NTDs. © 2015 Wiley Periodicals, Inc.

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