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Jeremic V.,University of Belgrade | Seke K.,Institute Of Public Health Of Serbia Dr Milan Jovanovic Batut | Radojicic Z.,University of Belgrade | Jeremic D.,University of Belgrade | And 3 more authors.
HealthMED | Year: 2011

We examined the health status of 27 European Union countries by employing statistical I-distance method on various health indicators. Results showed that Ireland tops the list of EU "healthiest countries", while Sweden and Finland are just a small step behind. On the other hand, Bulgaria, Hungary, Poland and Romania are at the bottom of the list. Further on, I-distance method has provided information as to which input variables are crucial for determining a country's health system performance. We emphasize importance of evaluating health system performances and determining key health indicators.

Jovanovic D.D.,Institute Of Public Health Of Serbia Dr Milan Jovanovic Batut | Paunovic K.,University of Belgrade | Manojlovic D.D.,Serbian Institute of Chemistry | Jakovljevic B.,University of Belgrade | And 2 more authors.
Environmental Research | Year: 2012

Background: Arsenic is constantly present in drinking water supply systems of Zrenjanin municipality across decades. It presents a great public health problem in Serbia, but its relationship with acute coronary syndrome (ACS) has not been studied previously. Objectives: The aims of this study were to assess the incidence of ACS in two areas from Zrenjanin municipality consuming different levels of arsenic in drinking water, and to explore the association between arsenic exposure and the probability of fatal outcome of ACS. Methods: The research was a registry-based ecological study of two populations consuming water with different arsenic levels, based on current guidelines (10 μg/L). Median arsenic in the area above national standard was 80 μg/L; median arsenic in the other area was 1 μg/L. Newly diagnosed cases of ACS were obtained from the National Registry for Acute Coronary Syndrome from 2006 to 2010. Results: The two populations were comparable by age, gender, and prevalence of risk factors for ACS. Standardized incidence rates (SIR) of ACS were higher for people consuming arsenic above standard (average five-year SIR was 237.00 per 100.000; 95% CI=214.93-260.74), in comparison to people consuming arsenic within limits (average SIR=124.40 per 100.000; 95% CI=96.00-158.56). Exposure to arsenic above limits was insignificantly associated with fatal outcome of ACS for the whole population, men and women. Conclusions: Consumption of arsenic above national standards was associated with higher risk for the occurrence of acute coronary syndrome and with insignificantly higher probability of fatal outcome of ACS in Zrenjanin municipality. © 2012 Elsevier Inc.

Maksimovic M.Z.,University of Belgrade | Gudelj Rakic J.M.,Institute Of Public Health Of Serbia Dr Milan Jovanovic Batut | Vlajinac H.D.,University of Belgrade | Vasiljevic N.D.,University of Belgrade | Marinkovic J.M.,University of Belgrade
International Journal of Public Health | Year: 2016

Objectives: To determine relationship between health behaviour and body mass index (BMI) in a Serbian adult population. Methods: Study population included adults aged 20 and more years. A stratified, two-stage national representative random sampling approach was used for the selection of the survey sample. Results: Regarding BMI, out of the 12,461 subjects of both sexes, 2.4 % were underweight, 36.5 % overweight and 22.4 % obese. Multivariate logistic regression analysis showed that both in men and women, risk factors for obesity were former smoking, irregular eating breakfast and low physical activity level, while in women only risk of obesity was associated with alcohol consumption. In both sexes, risk factors for overweight were former smoking and low physical activity level, and in women additionally those were alcohol consumption, irregular eating breakfast, always adding salt to meals and consumption of 2–4 portions of fruit daily. Smoking and irregular eating of breakfast in men were risk factors for underweight. Conclusions: Physical activity, alcohol consumption, smoking, irregular breakfast consumption, adding salt to meals, frequency of vegetable and fruit consumption were related to BMI in adult Serbian population. © 2015, Swiss School of Public Health (SSPH+).

Jovanovic D.,Institute Of Public Health Of Serbia Dr Milan Jovanovic Batut | Rasic-Milutinovic Z.,University of Belgrade | Paunovic K.,Institute of Hygiene and Medical Ecology | Jakovljevic B.,Institute of Hygiene and Medical Ecology | And 2 more authors.
International Journal of Hygiene and Environmental Health | Year: 2013

Arsenic in drinking water presents a serious public health problem in Serbia, but its relationship with diabetes has not been studied previously. The aim of this study was to explore the association between exposure to arsenic in drinking water and the occurrence of type 2 diabetes in Middle Banat region, Serbia. This cross-sectional study comprised two populations. Exposed population in Middle Banat region consumes drinking water with arsenic (mean = 56. μg/L); unexposed population from six regions in Central Serbia consumes arsenic below detection limit (2. μg/L). Newly diagnosed cases of type 2 diabetes were obtained from the National Registry of Diabetes in 2008. The Registry included age, gender, family history of diabetes, presence of overweight, central obesity, cholesterol and triglyceride levels. In addition, the number of cases of diabetes reported in years 2006, 2007 and 2009 was used to calculate standardized incidence rates for both populations. Two populations were comparable by age, family history of diabetes and prevalence of overweight persons. Unexposed population was more likely to have central obesity, and high total cholesterol and triglycerides. Standardized incidence rates of type 2 diabetes were higher in exposed population. Odds ratios for type 2 diabetes were significantly higher for the exposed population, both men and women, in the period from 2006 to 2009, when compared with the unexposed population. The population from Middle Banat region, consuming drinking water with low levels of arsenic, was at higher risk for the occurrence of type 2 diabetes in comparison to the unexposed population in Central Serbia. © 2012 Elsevier GmbH.

Velhner M.,Scientific Veterinary Institute Novi Sad | Kozoderovic G.,Institute of Public Health of Vojvodina | Grego E.,Institute Of Public Health Of Serbia Dr Milan Jovanovic Batut | Galic N.,Institute Of Public Health Of Serbia Dr Milan Jovanovic Batut | And 3 more authors.
Zoonoses and Public Health | Year: 2014

Quinolone-resistant Salmonella Infantis (n = 64) isolated from human stool samples, food and poultry during the years 2006-2011 were analysed for their resistance phenotypes, macrorestriction patterns and molecular mechanisms of decreased susceptibility to fluoroquinolones. Minimum inhibitory concentrations (MICs) of nalidixic acid (NAL) and ciprofloxacin (CIP) were determined by the agar dilution procedure, and the susceptibility to additional antimicrobial agents was determined by the disc diffusion method. To assess the influence of enhanced efflux activity, MICs were determined in the presence and absence of the inhibitor PAβN. The results of pulsed-field gel electrophoresis (PFGE) typing revealed that quinolone-resistant S. Infantis in Serbia had similar or indistinguishable PFGE profiles, suggesting a clonal spread. All S. Infantis showed combined resistance to NAL and tetracycline, whereas multiple drug resistance to three or more antibiotic classes was rare (2 isolates of human origin). The MICs ranged between 512 and 1024 μg/mL for NAL and 0.125-2 μg/mL for CIP. A single-point mutation in the gene gyrA leading to a Ser83→Tyr exchange was detected in all isolates, and a second exchange (Ser80→Arg) in the gene parC was only present in eight S. Infantis isolates exhibiting slightly higher MICs of CIP (2 μg/mL). The inhibitor PAβN decreased the MIC values of CIP by two dilution steps and of NAL by at minimum 3-6 dilution steps, indicating that enhanced efflux plays an important role in quinolone resistance in these isolates. The plasmid-mediated genes qnr, aac(6′)-lb-cr and qepA were not detected by PCR assays. © 2013 Blackwell Verlag GmbH.

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