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Hartley S.,University of East Anglia | Hartley S.,University of Sydney | Hartley S.,London School of Hygiene and Tropical Medicine | McArthur M.,University of East Anglia | And 9 more authors.
PLoS ONE | Year: 2014

Background: People with brain disorders - defined as both, mental disorders and neurological disorders experience a wide range of psychosocial difficulties (PSDs) (e.g., concentrating, maintaining energy levels, and maintaining relationships). Research evidence is required to show that these PSDs are common across brain disorders. Objectives: To explore and gain deeper understanding of the experiences of people with seven brain disorders (alcohol dependency, depression, epilepsy, multiple sclerosis, Parkinson's disease, schizophrenia, stroke). It examines the common PSDs and their influencing factors. Methods: Seventy seven qualitative studies identified in a systematic literature review and qualitative data derived from six focus groups are used to generate first-person narratives representing seven brain disorders. A theory-driven thematic analysis of these narratives identifies the PSDs and their influencing factors for comparison between the seven disorders. Results: First-person narratives illustrate realities for people with brain disorders facilitating a deeper understanding of their every-day life experiences. Thematic analysis serves to highlight the commonalities, both of PSDs, such as loneliness, anger, uncertainty about the future and problems with work activities, and their determinants, such as work opportunities, trusting relationships and access to self-help groups. Conclusions: The strength of the methodology and the narratives is that they provide the opportunity for the reader to empathise with people with brain disorders and facilitate deeper levels of understanding of the complexity of the relationship of PSDs, determinants and facilitators. The latter reflect positive aspects of the lives of people with brain disorders. The result that many PSDs and their influencing factors are common to people with different brain disorders opens up the door to the possibility of using cross-cutting interventions involving different sectors. This strengthens the message that 'a great deal can be done' to improve the lived experience of persons with brain disorders when medical interventions are exhausted. © 2014 Hartley et al.

PubMed | Institute of Neurology and Psychiatry
Type: Journal Article | Journal: Journal of youth and adolescence | Year: 2013

Sixty proband children (P) of bipolar I parents and 60 control children of normal parents (C), in the age range 10-17, were investigated clinically by K-SADS-E interview and psychologically by personality inventories. In the global psychopathology rate of 63% in P children and 25% in C children, depressive disorders reached 8% in P children and 0% in C children, while depressive personality traits reached 22% in P children and 15% in C children. Cluster analysis evidenced a variety of personality structures, but 3 clusters were striking: a cluster characterized by high anxiety and depressive reactivity (17% P and 5% C children), a cluster characterized by high depressive reactivity and emotional instability (5% P children), and a hyperthymic cluster (5 % P children). Sixty-seven percent of P children and 36% of C children showed deviant personality traits (p<.01).

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